PEGylation as a strategy for improving nanoparticle-based drug and gene delivery
Suk, Jung Soo, Xu, Qingguo, Kim, Namho, Hanes, Justin, Ensign, Laura M.
Published in Advanced drug delivery reviews (01.04.2016)
Published in Advanced drug delivery reviews (01.04.2016)
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Brain-Penetrating Nanoparticles Improve Paclitaxel Efficacy in Malignant Glioma Following Local Administration
Nance, Elizabeth, Zhang, Clark, Shih, Ting-Yu, Xu, Qingguo, Schuster, Benjamin S, Hanes, Justin
Published in ACS nano (28.10.2014)
Published in ACS nano (28.10.2014)
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Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo
Xu, Qingguo, Ensign, Laura M, Boylan, Nicholas J, Schön, Arne, Gong, Xiaoqun, Yang, Jeh-Chang, Lamb, Nicholas W, Cai, Shutian, Yu, Tao, Freire, Ernesto, Hanes, Justin
Published in ACS nano (22.09.2015)
Published in ACS nano (22.09.2015)
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A dense poly(ethylene glycol) coating improves penetration of large polymeric nanoparticles within brain tissue
Nance, Elizabeth A, Woodworth, Graeme F, Sailor, Kurt A, Shih, Ting-Yu, Xu, Qingguo, Swaminathan, Ganesh, Xiang, Dennis, Eberhart, Charles, Hanes, Justin
Published in Science translational medicine (29.08.2012)
Published in Science translational medicine (29.08.2012)
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Validation of hyaluronic acid-agar-based hydrogels as vitreous humor mimetics for in vitro drug and particle migration evaluations
Thakur, Sachin S., Shenoy, Siddharth K., Suk, Jung Soo, Hanes, Justin S., Rupenthal, Ilva D.
Published in European journal of pharmaceutics and biopharmaceutics (01.03.2020)
Published in European journal of pharmaceutics and biopharmaceutics (01.03.2020)
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Highly compacted biodegradable DNA nanoparticles capable of overcoming the mucus barrier for inhaled lung gene therapy
Mastorakos, Panagiotis, Adriana L. da Silva, Jane Chisholm, Eric Song, Won Kyu Choi, Michael P. Boyle, Marcelo M. Morales, Justin Hanes, Jung Soo Suk
Published in Proceedings of the National Academy of Sciences - PNAS (14.07.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (14.07.2015)
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Journal Article
Convection enhanced delivery of cisplatin-loaded brain penetrating nanoparticles cures malignant glioma in rats
Zhang, Clark, Nance, Elizabeth A., Mastorakos, Panagiotis, Chisholm, Jane, Berry, Sneha, Eberhart, Charles, Tyler, Betty, Brem, Henry, Suk, Jung Soo, Hanes, Justin
Published in Journal of controlled release (10.10.2017)
Published in Journal of controlled release (10.10.2017)
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Novel Focused Ultrasound Gene Therapy Approach Noninvasively Restores Dopaminergic Neuron Function in a Rat Parkinson’s Disease Model
Mead, Brian P, Kim, Namho, Miller, G. Wilson, Hodges, David, Mastorakos, Panagiotis, Klibanov, Alexander L, Mandell, James W, Hirsh, Jay, Suk, Jung Soo, Hanes, Justin, Price, Richard J
Published in Nano letters (14.06.2017)
Published in Nano letters (14.06.2017)
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Immunomodulation-accelerated neuronal regeneration following selective rod photoreceptor cell ablation in the zebrafish retina
White, David T., Sengupta, Sumitra, Saxena, Meera T., Xu, Qingguo, Hanes, Justin, Ding, Ding, Ji, Hongkai, Mumm, Jeff S.
Published in Proceedings of the National Academy of Sciences - PNAS (02.05.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (02.05.2017)
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Non-invasive delivery of stealth, brain-penetrating nanoparticles across the blood-brain barrier using MRI-guided focused ultrasound
Nance, Elizabeth, Timbie, Kelsie, Miller, G Wilson, Song, Ji, Louttit, Cameron, Klibanov, Alexander L, Shih, Ting-Yu, Swaminathan, Ganesh, Tamargo, Rafael J, Woodworth, Graeme F, Hanes, Justin, Price, Richard J
Published in Journal of controlled release (10.09.2014)
Published in Journal of controlled release (10.09.2014)
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Journal Article
Enhanced vaginal drug delivery through the use of hypotonic formulations that induce fluid uptake
Ensign, Laura M, Hoen, Timothy E, Maisel, Katharina, Cone, Richard A, Hanes, Justin S
Published in Biomaterials (01.09.2013)
Published in Biomaterials (01.09.2013)
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Mucus-penetrating nanoparticles for vaginal drug delivery protect against herpes simplex virus
Ensign, Laura M, Tang, Benjamin C, Wang, Ying-Ying, Tse, Terence A, Hoen, Timothy, Cone, Richard, Hanes, Justin
Published in Science translational medicine (13.06.2012)
Published in Science translational medicine (13.06.2012)
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Journal Article
Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier
Tang, Benjamin C, Dawson, Michelle, Lai, Samuel K, Wang, Ying-Ying, Suk, Jung Soo, Yang, Ming, Zeitlin, Pamela, Boyle, Michael P, Fu, Jie, Hanes, Justin
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2009)
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Sustained treatment of retinal vascular diseases with self-aggregating sunitinib microparticles
Tsujinaka, Hiroki, Fu, Jie, Shen, Jikui, Yu, Yun, Hafiz, Zibran, Kays, Joshua, McKenzie, David, Cardona, Delia, Culp, David, Peterson, Ward, Gilger, Brian C., Crean, Christopher S., Zhang, Jin-Zhong, Kanan, Yogita, Yu, Weiling, Cleland, Jeffrey L., Yang, Ming, Hanes, Justin, Campochiaro, Peter A.
Published in Nature communications (04.02.2020)
Published in Nature communications (04.02.2020)
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Disulfide disruption reverses mucus dysfunction in allergic airway disease
Morgan, Leslie E., Jaramillo, Ana M., Shenoy, Siddharth K., Raclawska, Dorota, Emezienna, Nkechinyere A., Richardson, Vanessa L., Hara, Naoko, Harder, Anna Q., NeeDell, James C., Hennessy, Corinne E., El-Batal, Hassan M., Magin, Chelsea M., Grove Villalon, Diane E., Duncan, Gregg, Hanes, Justin S., Suk, Jung Soo, Thornton, David J., Holguin, Fernando, Janssen, William J., Thelin, William R., Evans, Christopher M.
Published in Nature communications (11.01.2021)
Published in Nature communications (11.01.2021)
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Journal Article
Rapid Transport of Large Polymeric Nanoparticles in Fresh Undiluted Human Mucus
Lai, Samuel K., O'Hanlon, D. Elizabeth, Harrold, Suzanne, Man, Stan T., Wang, Ying-Ying, Cone, Richard, Hanes, Justin
Published in Proceedings of the National Academy of Sciences - PNAS (30.01.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (30.01.2007)
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Journal Article
Nanoparticle penetration of human cervicovaginal mucus: The effect of polyvinyl alcohol
Yang, Ming, Lai, Samuel K., Yu, Tao, Wang, Ying-Ying, Happe, Christina, Zhong, Weixi, Zhang, Michael, Anonuevo, Abraham, Fridley, Colleen, Hung, Amy, Fu, Jie, Hanes, Justin
Published in Journal of controlled release (28.10.2014)
Published in Journal of controlled release (28.10.2014)
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Journal Article
Hyaluronan in cervical epithelia protects against infection-mediated preterm birth
Akgul, Yucel, Word, R Ann, Ensign, Laura M, Yamaguchi, Yu, Lydon, John, Hanes, Justin, Mahendroo, Mala
Published in The Journal of clinical investigation (01.12.2014)
Published in The Journal of clinical investigation (01.12.2014)
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