Discovery of E2730, a novel selective uncompetitive GAT1 inhibitor, as a candidate for anti‐seizure medication
Fukushima, Kazuyuki, Higashiyama, Hiroyuki, Kazuta, Yuji, Hashimoto, Keisuke, Watanabe, Naoto, Furuya, Yoshiaki, Ito, Yoshimasa, Wu, Ting, Kosasa, Takashi, Talos, Delia M., Song, Yeri, Roberts, Nicholas S., Jensen, Frances E., Hanada, Takahisa, Ido, Katsutoshi
Published in Epilepsia open (01.09.2023)
Published in Epilepsia open (01.09.2023)
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Synthesis of 11C‑Labeled RXR Partial Agonist 1‑[(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)amino]benzotriazole-5-carboxylic Acid (CBt-PMN) by Direct [11C]Carbon Dioxide Fixation via Organolithiation of Trialkyltin Precursor and PET Imaging Thereof
Shibahara, Osamu, Watanabe, Masaki, Yamada, Shoya, Akehi, Masaru, Sasaki, Takanori, Akahoshi, Akiya, Hanada, Takahisa, Hirano, Hiroyuki, Nakatani, Shunsuke, Nishioka, Hiromi, Takeuchi, Yasuo, Kakuta, Hiroki
Published in Journal of medicinal chemistry (24.08.2017)
Published in Journal of medicinal chemistry (24.08.2017)
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Positron Emission Tomography to Elucidate Pharmacokinetic Differences of Regioisomeric Retinoid X Receptor Agonists
Kobayashi, Toshiki, Furusawa, Yuki, Yamada, Shoya, Akehi, Masaru, Takenaka, Fumiaki, Sasaki, Takanori, Akahoshi, Akiya, Hanada, Takahisa, Matsuura, Eiji, Hirano, Hiroyuki, Tai, Akihiro, Kakuta, Hiroki
Published in ACS medicinal chemistry letters (12.03.2015)
Published in ACS medicinal chemistry letters (12.03.2015)
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Anti-high Mobility Group Box 1 Antibody Ameliorates Albuminuria in MRL/ lpr Lupus-Prone Mice
Watanabe, Haruki, Watanabe, Katsue S, Liu, Keyue, Hiramatsu, Sumie, Zeggar, Sonia, Katsuyama, Eri, Tatebe, Noriko, Akahoshi, Akiya, Takenaka, Fumiaki, Hanada, Takahisa, Akehi, Masaru, Sasaki, Takanori, Sada, Ken-Ei, Matsuura, Eiji, Nishibori, Masahiro, Wada, Jun
Published in Molecular therapy. Methods & clinical development (15.09.2017)
Published in Molecular therapy. Methods & clinical development (15.09.2017)
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The Function of β2-glycoprotein I in Angiogenesis and Its in Vivo Distribution in Tumor Xenografts
Wahyuningsih, Arum Tri, Shen, Lianhua, Kobayashi, Kazuko, Sasaki, Takanori, Takenaka, Fumiaki, Hanada, Takahisa, Akehi, Masaru, Akahoshi, Akiya, Ozeki, Eiichi, Ando, Eiji, Matsuura, Eiji
Published in Acta medica Okayama (2016)
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Published in Acta medica Okayama (2016)
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Perampanel: A novel, orally active, noncompetitive AMPA‐receptor antagonist that reduces seizure activity in rodent models of epilepsy
Hanada, Takahisa, Hashizume, Yutaka, Tokuhara, Naoki, Takenaka, Osamu, Kohmura, Naohiro, Ogasawara, Aichi, Hatakeyama, Shinji, Ohgoh, Makoto, Ueno, Masataka, Nishizawa, Yukio
Published in Epilepsia (Copenhagen) (01.07.2011)
Published in Epilepsia (Copenhagen) (01.07.2011)
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Discovery of 2‑(2-Oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl)benzonitrile (Perampanel): A Novel, Noncompetitive α‑Amino-3-hydroxy-5-methyl-4-isoxazolepropanoic Acid (AMPA) Receptor Antagonist
Hibi, Shigeki, Ueno, Koshi, Nagato, Satoshi, Kawano, Koki, Ito, Koichi, Norimine, Yoshihiko, Takenaka, Osamu, Hanada, Takahisa, Yonaga, Masahiro
Published in Journal of medicinal chemistry (13.12.2012)
Published in Journal of medicinal chemistry (13.12.2012)
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Ultra-high-dose methylcobalamin in amyotrophic lateral sclerosis: a long-term phase II/III randomised controlled study
Kaji, Ryuji, Imai, Takashi, Iwasaki, Yasuo, Okamoto, Koichi, Nakagawa, Masanori, Ohashi, Yasuo, Takase, Takao, Hanada, Takahisa, Shimizu, Hiroki, Tashiro, Kunio, Kuzuhara, Shigeki
Published in Journal of neurology, neurosurgery and psychiatry (01.04.2019)
Published in Journal of neurology, neurosurgery and psychiatry (01.04.2019)
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The neuroprotective effect of perampanel in lithium-pilocarpine rat seizure model
Wu, Ting, Ido, Katsutoshi, Osada, Yoshihide, Kotani, Sadaharu, Tamaoka, Akira, Hanada, Takahisa
Published in Epilepsy research (01.11.2017)
Published in Epilepsy research (01.11.2017)
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Synthesis of C-11-Labeled RXR Partial Agonist 14(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)aminoThenzotriazole-5-carboxylic Acid (CBt-PMN) by Direct [C-11]Carbon Dioxide Fixation via Organolithiation of Trialkyltin Precursor and PET Imaging Thereof
Shibahara, Osamu, Watanabe, Masaki, Yamada, Shoya, Akehi, Masaru, Sasaki, Takanori, Akahoshi, Akiya, Hanada, Takahisa, Hirano, Hiroyuki, Nakatani, Shunsuke, Nishioka, Hiromi, Takeuchi, Yasuo, Kakuta, Hiroki
Published in Journal of medicinal chemistry (24.08.2017)
Published in Journal of medicinal chemistry (24.08.2017)
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