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Synthesis and biological evaluation of platensimycin analogs
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Cytochrome P450 3A4-Mediated Bioactivation of Raloxifene: Irreversible Enzyme Inhibition and Thiol Adduct Formation
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Discovery of MK-7655, a β-lactamase inhibitor for combination with Primaxin
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Published in Bioorganic & medicinal chemistry letters (01.02.2014)
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2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: Scaffold design and advancement in HDLc-raising efficacy
Sweis, Ramzi F., Hunt, Julianne A., Kallashi, Florida, Hammond, Milton L., Chen, Ying, Eveland, Suzanne S., Guo, Qiu, Hyland, Sheryl A., Milot, Denise P., Cumiskey, Anne-Marie, Latham, Melanie, Rosa, Raymond, Peterson, Larry, Sparrow, Carl P., Wright, Samuel D., Anderson, Matt S., Sinclair, Peter J.
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
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Shen, Hong C, Ding, Fa-Xiang, Luell, Silvi, Forrest, Michael J, Carballo-Jane, Ester, Wu, Kenneth K, Wu, Tsuei-Ju, Cheng, Kang, Wilsie, Larissa C, Krsmanovic, Mihajlo L, Taggart, Andrew K, Ren, Ning, Cai, Tian-Quan, Deng, Qiaolin, Chen, Qing, Wang, Junying, Wolff, Michael S, Tong, Xinchun, Holt, Tom G, Waters, M. Gerard, Hammond, Milton L, Tata, James R, Colletti, Steven L
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Novel N-Arylpyrazolo[3,2-c]-Based Ligands for the Glucocorticoid Receptor: Receptor Binding and in Vivo Activity
Ali, Amjad, Thompson, Christopher F, Balkovec, James M, Graham, Donald W, Hammond, Milton L, Quraishi, Nazia, Tata, James R, Einstein, Monica, Ge, Lan, Harris, Georgianna, Kelly, Terri M, Mazur, Paul, Pandit, Shilpa, Santoro, Joseph, Sitlani, Ayesha, Wang, Chuanlin, Williamson, Joanne, Miller, Douglas K, Thompson, Chris M, Zaller, Dennis M, Forrest, Michael J, Carballo-Jane, Ester, Luell, Silvi
Published in Journal of medicinal chemistry (06.05.2004)
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In Vitro Bioactivation of Dihydrobenzoxathiin Selective Estrogen Receptor Modulators by Cytochrome P450 3A4 in Human Liver Microsomes: Formation of Reactive Iminium and Quinone Type Metabolites
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Published in Chemical research in toxicology (01.04.2005)
Published in Chemical research in toxicology (01.04.2005)
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Estrogen receptor ligands. Part 3: The SAR of dihydrobenzoxathiin SERMs
Chen, Helen Y., Kim, Seongkon, Wu, Jane Y., Birzin, Elizabeth T., Chan, Wanda, Yang, Yi Tien, Dahllund, Johanna, DiNinno, Frank, Rohrer, Susan P., Schaeffer, James M., Hammond, Milton L.
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Published in Bioorganic & medicinal chemistry letters (01.02.2005)
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Estrogen receptor ligands. Part 14: Application of novel antagonist side chains to existing platforms
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Published in Bioorganic & medicinal chemistry letters (01.12.2005)
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6H-Benzo[c]chromen-6-one derivatives as selective ERβ agonists
Sun, Wanying, Cama, Lovji D., Birzin, Elizabeth T., Warrier, Sudha, Locco, Louis, Mosley, Ralph, Hammond, Milton L., Rohrer, Susan P.
Published in Bioorganic & medicinal chemistry letters (15.03.2006)
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Discovery of Novel Tricyclic Full Agonists for the G-Protein-Coupled Niacin Receptor 109A with Minimized Flushing in Rats
Shen, Hong C, Ding, Fa-Xiang, Deng, Qiaolin, Wilsie, Larissa C, Krsmanovic, Mihajlo L, Taggart, Andrew K, Carballo-Jane, Ester, Ren, Ning, Cai, Tian-Quan, Wu, Tsuei-Ju, Wu, Kenneth K, Cheng, Kang, Chen, Qing, Wolff, Michael S, Tong, Xinchun, Holt, Tom G, Waters, M. Gerard, Hammond, Milton L, Tata, James R, Colletti, Steven L
Published in Journal of medicinal chemistry (23.04.2009)
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Discovery of a Biaryl Cyclohexene Carboxylic Acid (MK-6892): A Potent and Selective High Affinity Niacin Receptor Full Agonist with Reduced Flushing Profiles in Animals as a Preclinical Candidate
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Side chain SAR of bicyclic β-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712
Chen, Helen, Blizzard, Timothy A., Kim, Seongkon, Wu, Jane, Young, Katherine, Park, Young-Whan, Ogawa, Aimie M., Raghoobar, Susan, Painter, Ronald E., Wisniewski, Doug, Hairston, Nichelle, Fitzgerald, Paula, Sharma, Nandini, Scapin, Giovanna, Lu, Jun, Hermes, Jeff, Hammond, Milton L.
Published in Bioorganic & medicinal chemistry letters (15.07.2011)
Published in Bioorganic & medicinal chemistry letters (15.07.2011)
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2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety
Smith, Cameron J., Ali, Amjad, Chen, Liya, Hammond, Milton L., Anderson, Matt S., Chen, Ying, Eveland, Suzanne S., Guo, Qiu, Hyland, Sheryl A., Milot, Denise P., Sparrow, Carl P., Wright, Samuel D., Sinclair, Peter J.
Published in Bioorganic & medicinal chemistry letters (2010)
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2-Arylbenzoxazoles as CETP inhibitors: Raising HDL-C in cynoCETP transgenic mice
Kallashi, Florida, Kim, Dooseop, Kowalchick, Jennifer, Park, You Jung, Hunt, Julianne A., Ali, Amjad, Smith, Cameron J., Hammond, Milton L., Pivnichny, James V., Tong, Xinchun, Xu, Suoyu S., Anderson, Matt S., Chen, Ying, Eveland, Suzanne S., Guo, Qiu, Hyland, Sheryl A., Milot, Denise P., Cumiskey, Anne-Marie, Latham, Melanie, Peterson, Laurence B., Rosa, Raymond, Sparrow, Carl P., Wright, Samuel D., Sinclair, Peter J.
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
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Synthesis and Antifungal Activity of Novel Cationic Pneumocandin Bo Derivatives
Bouffard, F. Aileen, Zambias, Robert A, Dropinski, James F, Balkovec, James M, Hammond, Milton L, Abruzzo, George K, Bartizal, Kenneth F, Marrinan, Jean A, Kurtz, Myra B
Published in Journal of medicinal chemistry (01.01.1994)
Published in Journal of medicinal chemistry (01.01.1994)
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Side chain SAR of bicyclic β-lactamase inhibitors (BLIs). 1. Discovery of a class C BLI for combination with imipinem
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Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
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