Development of a Small-Molecule Serum-and Glucocorticoid-Regulated Kinase-1 Antagonist and Its Evaluation as a Prostate Cancer Therapeutic
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Published in Cancer research (Chicago, Ill.) (15.09.2008)
Published in Cancer research (Chicago, Ill.) (15.09.2008)
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Development of an Enantioselective Synthetic Route to Neocarzinostatin Chromophore and Its Use for Multiple Radioisotopic Incorporation
Myers, Andrew G., Glatthar, Ralf, Hammond, Marlys, Harrington, Philip M., Kuo, Elaine Y., Liang, Jun, Schaus, Scott E., Wu, Yusheng, Xiang, Jia-Ning
Published in Journal of the American Chemical Society (15.05.2002)
Published in Journal of the American Chemical Society (15.05.2002)
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Total Synthesis of (+)-Neocarzinostatin Chromophore
Myers, Andrew G, Liang, Jun, Hammond, Marlys, Harrington, Philip M, Wu, Yusheng, Kuo, Elaine Y
Published in Journal of the American Chemical Society (03.06.1998)
Published in Journal of the American Chemical Society (03.06.1998)
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Enantioselective Synthesis of Neocarzinostatin Chromophore Aglycon
Myers, Andrew G, Hammond, Marlys, Wu, Yusheng, Xiang, Jia-Ning, Harrington, Philip M, Kuo, Elaine Y
Published in Journal of the American Chemical Society (16.10.1996)
Published in Journal of the American Chemical Society (16.10.1996)
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Identification of Purines and 7‑Deazapurines as Potent and Selective Type I Inhibitors of Troponin I‑Interacting Kinase (TNNI3K)
Lawhorn, Brian G, Philp, Joanne, Zhao, Yongdong, Louer, Christopher, Hammond, Marlys, Cheung, Mui, Fries, Harvey, Graves, Alan P, Shewchuk, Lisa, Wang, Liping, Cottom, Joshua E, Qi, Hongwei, Zhao, Huizhen, Totoritis, Rachel, Zhang, Guofeng, Schwartz, Benjamin, Li, Hu, Sweitzer, Sharon, Holt, Dennis A, Gatto, Gregory J, Kallander, Lara S
Published in Journal of medicinal chemistry (24.09.2015)
Published in Journal of medicinal chemistry (24.09.2015)
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Discovery of GSK2798745: A Clinical Candidate for Inhibition of Transient Receptor Potential Vanilloid 4 (TRPV4)
Brooks, Carl A, Barton, Linda S, Behm, David J, Eidam, Hilary S, Fox, Ryan M, Hammond, Marlys, Hoang, Tram H, Holt, Dennis A, Hilfiker, Mark A, Lawhorn, Brian G, Patterson, Jaclyn R, Stoy, Patrick, Roethke, Theresa J, Ye, Guosen, Zhao, Steve, Thorneloe, Kevin S, Goodman, Krista B, Cheung, Mui
Published in ACS medicinal chemistry letters (08.08.2019)
Published in ACS medicinal chemistry letters (08.08.2019)
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Synthetic aspects of an asymmetric nitrogen-insertion process: preparation of chiral, non-racemic caprolactams and valerolactams. Total synthesis of (-)-alloyohimbane
Aube, Jeffrey, Wang, Yuguang, Hammond, Marlys, Tanol, Mehmet, Takusagawa, Fusao, Vander Velde, David
Published in Journal of the American Chemical Society (01.06.1990)
Published in Journal of the American Chemical Society (01.06.1990)
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Reverse Hydroxamate Inhibitors of Bone Morphogenetic Protein 1
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Published in ACS medicinal chemistry letters (12.07.2018)
Published in ACS medicinal chemistry letters (12.07.2018)
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Syntheses and rearrangements of spirocyclic oxaziridines derived from unsymmetrical ketones
Aube, Jeffrey, Hammond, Marlys, Gherardini, Elyse, Takusagawa, Fusao
Published in Journal of organic chemistry (01.01.1991)
Published in Journal of organic chemistry (01.01.1991)
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Design and synthesis of orally bioavailable serum and glucocorticoid-regulated kinase 1 (SGK1) inhibitors
Hammond, Marlys, Washburn, David G., Hoang, Tram H., Manns, Sharada, Frazee, James S., Nakamura, Hiroko, Patterson, Jaclyn R., Trizna, Walter, Wu, Charlene, Azzarano, Leonard M., Nagilla, Rakesh, Nord, Melanie, Trejo, Rebecca, Head, Martha S., Zhao, Baoguang, Smallwood, Angela M., Hightower, Kendra, Laping, Nicholas J., Schnackenberg, Christine G., Thompson, Scott K.
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
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2-Amino-9-aryl-3-cyano-4-methyl-7-oxo-6,7,8,9-tetrahydropyrido[2′,3′:4,5]thieno[2,3- b]pyridine derivatives as selective progesterone receptor agonists
Wang, Yonghui, Duraiswami, Chaya, Madauss, Kevin P., Tran, Thuy B., Williams, Shawn P., Deng, Su-Jun, Graybill, Todd L., Hammond, Marlys, Jones, David G., Grygielko, Eugene T., Bray, Jeffrey D., Thompson, Scott K.
Published in Bioorganic & medicinal chemistry letters (01.09.2009)
Published in Bioorganic & medicinal chemistry letters (01.09.2009)
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Bioisosteric replacement of the hydrazide pharmacophore of the cannabinoid-1 receptor antagonist SR141716A. Part I: Potent, orally-active 1,4-disubstituted imidazoles
Dow, Robert L., Hadcock, John R., Scott, Dennis O., Schneider, Steven R., Paight, Ernest S., Iredale, Philip A., Carpino, Philip A., Griffith, David A., Hammond, Marlys, DaSilva-Jardine, Paul
Published in Bioorganic & medicinal chemistry letters (15.09.2009)
Published in Bioorganic & medicinal chemistry letters (15.09.2009)
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HYDROXY FORMAMIDE DERIVATIVES AND THEIR USE
HOANG TRAM H, LAWHORN BRIAN GRIFFIN, YE GUOSEN, DOWDELL SARAH E, ELBAN MARK, KALLANDER LARA S, WASHBURN DAVID G, PHILP JOANNE, HILFIKER MARK A, MANNS SHARADA, HAMMOND MARLYS, FOX RYAN MICHAEL, EIDAM HILARY SCHENCK
Year of Publication 12.09.2016
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Year of Publication 12.09.2016
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Synthesis and SAR of amino acid-derived heterocyclic progesterone receptor full and partial agonists
Hammond, Marlys, Patterson, Jaclyn R., Manns, Sharada, Hoang, Tram H., Washburn, David G., Trizna, Walter, Glace, Lindsay, Grygielko, Eugene T., Nagilla, Rakesh, Nord, Melanie, Fries, Harvey E., Minick, Douglas J., Laping, Nicholas J., Bray, Jeffrey D., Thompson, Scott K.
Published in Bioorganic & medicinal chemistry letters (15.05.2009)
Published in Bioorganic & medicinal chemistry letters (15.05.2009)
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Improving the developability profile of pyrrolidine progesterone receptor partial agonists
Kallander, Lara S., Washburn, David G., Hoang, Tram H., Frazee, James S., Stoy, Patrick, Johnson, Latisha, Lu, Qing, Hammond, Marlys, Barton, Linda S., Patterson, Jaclyn R., Azzarano, Leonard M., Nagilla, Rakesh, Madauss, Kevin P., Williams, Shawn P., Stewart, Eugene L., Duraiswami, Chaya, Grygielko, Eugene T., Xu, Xiaoping, Laping, Nicholas J., Bray, Jeffrey D., Thompson, Scott K.
Published in Bioorganic & medicinal chemistry letters (01.01.2010)
Published in Bioorganic & medicinal chemistry letters (01.01.2010)
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Discovery of orally active, pyrrolidinone-based progesterone receptor partial agonists
Washburn, David G., Hoang, Tram H., Frazee, James S., Johnson, Latisha, Hammond, Marlys, Manns, Sharada, Madauss, Kevin P., Williams, Shawn P., Duraiswami, Chaya, Tran, Thuy B., Stewart, Eugene L., Grygielko, Eugene T., Glace, Lindsay E., Trizna, Walter, Nagilla, Rakesh, Bray, Jeffrey D., Thompson, Scott K.
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
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TRPV4 ANTAGONISTS
GOODMAN KRISTA B, BROOKS CARL, STOY PATRICK, CHEUNG MUI, HOANG TRAM H, HILFIKER MARK A, YE GUOSEN, HAMMOND MARLYS, PATTERSON JACLYN R, EIDAM HILARY SCHENCK
Year of Publication 04.04.2014
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Year of Publication 04.04.2014
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Structure-activity relationship studies on 2-heteroaryl-4-arylimidazoles NPY5 receptor antagonists
ELLIOTT, Richard L, OLIVER, Robert M, MACK, Christine M, CASSELLA, James V, LAFLAMME, Janet A, GILLASPY, Melissa L, HAMMOND, Marlys, HANK, Richard F, MAURER, Tristan S, BAKER, Demetria L, DASILVA-JARDINE, Paul A, STEVENSON, Ralph W
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
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