A novel, multitargeted endogenous metabolic modulator composition impacts metabolism, inflammation, and fibrosis in nonalcoholic steatohepatitis-relevant primary human cell models
Daou, Nadine, Viader, Andreu, Cokol, Murat, Nitzel, Arianna, Chakravarthy, Manu V., Afeyan, Raffi, Tramontin, Tony, Marukian, Svetlana, Hamill, Michael J.
Published in Scientific reports (04.06.2021)
Published in Scientific reports (04.06.2021)
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Journal Article
Endogenous Metabolic Modulators: Emerging Therapeutic Potential of Amino Acids
Hamill, Michael J., Afeyan, Raffi, Chakravarthy, Manu V., Tramontin, Tony
Published in iScience (23.10.2020)
Published in iScience (23.10.2020)
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Journal Article
Crystallographic trapping in the rebeccamycin biosynthetic enzyme RebC
Ryan, Katherine S, Howard-Jones, Annaleise R, Hamill, Michael J, Elliott, Sean J, Walsh, Christopher T, Drennan, Catherine L
Published in Proceedings of the National Academy of Sciences - PNAS (25.09.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (25.09.2007)
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Journal Article
LIVRQNac (AXA1125) ENHANCES INSULIN SENSITIVITY IN PRIMARY HUMAN HEPATOCYTES AND IN SUBJECTS WITH NAFLD AND T2D
Baum, Seth J., Harrison, Stephen A., Gunn, Nadege T., Younes, Ziad H., Kohli, Anita, Patil, Rashmee, Fras, Juan P., Hamill, Michael, Daou, Nadine, Zhao, Jeff, Chakravarthy, Manu V., Koziel, Margaret J.
Published in American journal of preventive cardiology (01.09.2021)
Published in American journal of preventive cardiology (01.09.2021)
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Journal Article
Flavin-Induced Oligomerization in Escherichia coli Adaptive Response Protein AidB
Hamill, Michael J, Jost, Marco, Wong, Cintyu, Elliott, Sean J, Drennan, Catherine L
Published in Biochemistry (Easton) (22.11.2011)
Published in Biochemistry (Easton) (22.11.2011)
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Journal Article
Thioredoxin Reductase from Thermoplasma acidophilum: A New Twist on Redox Regulation
Hernandez, Hector H, Jaquez, Orlando A, Hamill, Michael J, Elliott, Sean J, Drennan, Catherine L
Published in Biochemistry (Easton) (16.09.2008)
Published in Biochemistry (Easton) (16.09.2008)
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Journal Article
Direct Electrochemical Analyses of a Thermophilic Thioredoxin Reductase: Interplay between Conformational Change and Redox Chemistry
Hamill, Michael J, Chobot, Sarah E, Hernandez, Hector H, Drennan, Catherine L, Elliott, Sean J
Published in Biochemistry (Easton) (16.09.2008)
Published in Biochemistry (Easton) (16.09.2008)
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Journal Article
LBP-31-AXA1665, a novel composition of amino acids restores the dysregulated amino acid profile, lowers ammonia, and improves body composition and function in Child-Pugh class A and B subjects
Chakravarthy, Manu, Confer, Scharmen, Neutel, Joel, Comb, William, Hamill, Michael, Carroll, Sean, Afeyan, Raffi, Sanyal, Arun
Published in Journal of hepatology (01.04.2019)
Published in Journal of hepatology (01.04.2019)
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Journal Article
The impact of a community pharmacy cough, cold and flu service on antibiotic prescribing and its acceptability
Published in Pharmaceutical journal
(01.03.2021)
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Journal Article
752-P: LIVRQNac (AXA1125) Enhances Insulin Sensitivity in Primary Human Hepatocytes and in Subjects with NAFLD and T2D
BAUM, SETH, HARRISON, STEPHEN A., GUNN, NADEGE T., YOUNES, ZIAD, KOHLI, ANITA, PATIL, RASHMEE, FRIAS, JUAN P., HAMILL, MICHAEL, DAOU, NADINE, ZHAO, JEFF, CHAKRAVARTHY, MANU, KOZIEL, MARGARET
Published in Diabetes (New York, N.Y.) (01.06.2021)
Published in Diabetes (New York, N.Y.) (01.06.2021)
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Journal Article
A Novel Composition of Endogenous Metabolic Modulators, AXA4010, Impacts Adhesion, Inflammation and RBC Membrane Deformability in Preclinical Models of Sickle Cell Disease
Hamill, Michael, Carroll, Sean, Wani, Revati, Russell, Matthew, Steuert, Zoe, Nitzel, Arianna, Downey, Andrew, Cokol, Murat, Afeyan, Raffi, Marukian, Svetlana, Tramontin, Tony
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
An Unusual Role for a Mobile Flavin in StaC-like Indolocarbazole Biosynthetic Enzymes
Goldman, Peter J., Ryan, Katherine S., Hamill, Michael J., Howard-Jones, Annaleise R., Walsh, Christopher T., Elliott, Sean J., Drennan, Catherine L.
Published in Chemistry & biology (27.07.2012)
Published in Chemistry & biology (27.07.2012)
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Journal Article
Safety, Tolerability, and Physiological Effects of AXA1665, a Novel Composition of Amino Acids, in Subjects With Child-Pugh A and B Cirrhosis
Chakravarthy, Manu V, Neutel, Joel, Confer, Scharmen, Zhao, Peng, Tatsuta, Noriaki, Rebello, Sam, Comb, William C, Hamill, Michael, Tramontin, Tony, Carroll, Sean, Afeyan, Raffi, Sanyal, Arun J
Published in Clinical and translational gastroenterology (01.08.2020)
Published in Clinical and translational gastroenterology (01.08.2020)
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Journal Article
아미노산 조성물 및 간 질환의 치료 방법
LUITHARDT HARRY, BERRY DAVID, LEE CHUNG WEI, HAMILL MICHAEL, AFEYAN RAFFI
Year of Publication 26.08.2019
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Year of Publication 26.08.2019
Patent
Flavin-Induced Oligomerization in Escherichia coli Adaptive Response Protein AidB
Hamill, Michael J., Jost, Marco, Wong, Cintyu, Elliott, Sean J., Drennan, Catherine L.
Published in Biochemistry (Easton) (27.10.2011)
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Published in Biochemistry (Easton) (27.10.2011)
Journal Article