Linker Length Modulates DNA Cross-Linking Reactivity and Cytotoxic Potency of C8/C8‘ Ether-Linked C2-exo-Unsaturated Pyrrolo[2,1-c][1,4]benzodiazepine (PBD) Dimers
Gregson, Stephen J, Howard, Philip W, Gullick, Darren R, Hamaguchi, Anzu, Corcoran, Kathryn E, Brooks, Natalie A, Hartley, John A, Jenkins, Terence C, Patel, Sejal, Guille, Matthew J, Thurston, David E
Published in Journal of medicinal chemistry (26.02.2004)
Published in Journal of medicinal chemistry (26.02.2004)
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DNA interstrand cross-linking and in vivo antitumor activity of the extended pyrrolo[2,1-c][1,4]benzodiazepine dimer SG2057
Hartley, John A., Hamaguchi, Anzu, Suggitt, Marie, Gregson, Stephen J., Thurston, David E., Howard, Philip W.
Published in Investigational new drugs (01.06.2012)
Published in Investigational new drugs (01.06.2012)
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SG2285, a Novel C2-Aryl-Substituted Pyrrolobenzodiazepine Dimer Prodrug That Cross-links DNA and Exerts Highly Potent Antitumor Activity
HARTLEY, John A, HAMAGUCHI, Anzu, PEPPER, Christopher, THET THET LIN, FEGAN, Christopher, THURSTON, David E, HOWARD, Philip W, COFFILS, Marissa, MARTIN, Christopher R. H, SUGGITT, Marie, ZHIZHI CHEN, GREGSON, Stephen J, MASTERSON, Luke A, TIBERGHIEN, Arnaud C, HARTLEY, Janet M
Published in Cancer research (Chicago, Ill.) (01.09.2010)
Published in Cancer research (Chicago, Ill.) (01.09.2010)
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SG2285, a novel C2-aryl-substituted pyrrolobenzodiazepine dimer pro-drug that cross-links DNA and exerts highly potent antitumor activity
Hartley, John A., Hamaguchi, Anzu, Coffils, Marissa, Martin, Christopher R.H., Suggitt, Marie, Chen, Zhizhi, Gregson, Stephen J., Masterson, Luke A., Tiberghien, Arnaud C., Hartley, Janet M., Pepper, Christopher, Lin, Thet Thet, Fegan, Christopher, Thurston, David E., Howard, Philip W.
Published in Cancer research (Chicago, Ill.) (26.07.2010)
Published in Cancer research (Chicago, Ill.) (26.07.2010)
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