The Viral Nucleoprotein Determines Mx Sensitivity of Influenza A Viruses
Zimmermann, Petra, Mänz, Benjamin, Haller, Otto, Schwemmle, Martin, Kochs, Georg
Published in Journal of Virology (01.08.2011)
Published in Journal of Virology (01.08.2011)
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Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import
Götz, Veronika, Magar, Linda, Dornfeld, Dominik, Giese, Sebastian, Pohlmann, Anne, Höper, Dirk, Kong, Byung-Whi, Jans, David A, Beer, Martin, Haller, Otto, Schwemmle, Martin
Published in Scientific reports (18.03.2016)
Published in Scientific reports (18.03.2016)
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Structural basis of oligomerization in the stalk region of dynamin-like MxA
Behlke, Joachim, Daumke, Oliver, Paeschke, Susann, Kochs, Georg, Gao, Song, Haller, Otto, von der Malsburg, Alexander
Published in Nature (London) (27.05.2010)
Published in Nature (London) (27.05.2010)
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Structure of Myxovirus Resistance Protein A Reveals Intra- and Intermolecular Domain Interactions Required for the Antiviral Function
Gao, Song, von der Malsburg, Alexander, Dick, Alexej, Faelber, Katja, Schröder, Gunnar F., Haller, Otto, Kochs, Georg, Daumke, Oliver
Published in Immunity (Cambridge, Mass.) (28.10.2011)
Published in Immunity (Cambridge, Mass.) (28.10.2011)
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Pandemic influenza A viruses escape from restriction by human MxA through adaptive mutations in the nucleoprotein
Mänz, Benjamin, Dornfeld, Dominik, Götz, Veronika, Zell, Roland, Zimmermann, Petra, Haller, Otto, Kochs, Georg, Schwemmle, Martin
Published in PLoS pathogens (01.03.2013)
Published in PLoS pathogens (01.03.2013)
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Evolution-Guided Identification of Antiviral Specificity Determinants in the Broadly Acting Interferon-Induced Innate Immunity Factor MxA
Mitchell, Patrick S., Patzina, Corinna, Emerman, Michael, Haller, Otto, Malik, Harmit S., Kochs, Georg
Published in Cell host & microbe (18.10.2012)
Published in Cell host & microbe (18.10.2012)
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In vivo evasion of MxA by avian influenza viruses requires human signature in the viral nucleoprotein
Deeg, Christoph M, Hassan, Ebrahim, Mutz, Pascal, Rheinemann, Lara, Götz, Veronika, Magar, Linda, Schilling, Mirjam, Kallfass, Carsten, Nürnberger, Cindy, Soubies, Sébastien, Kochs, Georg, Haller, Otto, Schwemmle, Martin, Staeheli, Peter
Published in The Journal of experimental medicine (01.05.2017)
Published in The Journal of experimental medicine (01.05.2017)
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Stalk Domain of the Dynamin-like MxA GTPase Protein Mediates Membrane Binding and Liposome Tubulation via the Unstructured L4 Loop
von der Malsburg, Alexander, Abutbul-Ionita, Inbal, Haller, Otto, Kochs, Georg, Danino, Dganit
Published in The Journal of biological chemistry (28.10.2011)
Published in The Journal of biological chemistry (28.10.2011)
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The nucleoprotein of newly emerged H7N9 influenza A virus harbors a unique motif conferring resistance to antiviral human MxA
Riegger, David, Hai, Rong, Dornfeld, Dominik, Mänz, Benjamin, Leyva-Grado, Victor, Sánchez-Aparicio, Maria T, Albrecht, Randy A, Palese, Peter, Haller, Otto, Schwemmle, Martin, García-Sastre, Adolfo, Kochs, Georg, Schmolke, Mirco
Published in Journal of virology (01.02.2015)
Published in Journal of virology (01.02.2015)
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Influenza A Virus Strains Differ in Sensitivity to the Antiviral Action of Mx-GTPase
DITTMANN, Jan, STERTZ, Silke, GRIMM, Daniel, STEEL, John, GARCIA-SASTRE, Adolfo, HALLER, Otto, KOCHS, Georg
Published in Journal of Virology (01.04.2008)
Published in Journal of Virology (01.04.2008)
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Adaptive Mutations Resulting in Enhanced Polymerase Activity Contribute to High Virulence of Influenza A Virus in Mice
ROLLING, Thierry, KOERNER, Iris, ZIMMERMANN, Petra, HOLZ, Kristian, HALLER, Otto, STAEHELI, Peter, KOCHS, Georg
Published in Journal of Virology (01.07.2009)
Published in Journal of Virology (01.07.2009)
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Induction of MxA Gene Expression by Influenza A Virus Requires Type I or Type III Interferon Signaling
HOLZINGER, Dirk, JORNS, Carl, STERTZ, Silke, BOISSON-DUPUIS, Stéphanie, THIMME, Robert, WEIDMANN, Manfred, CASANOVA, Jean-Laurent, HALLER, Otto, KOCHS, Georg
Published in Journal of Virology (01.07.2007)
Published in Journal of Virology (01.07.2007)
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Altered receptor specificity and fusion activity of the haemagglutinin contribute to high virulence of a mouse-adapted influenza A virus
KOERNER, Iris, MATROSOVICH, Mikhail N, HALLER, Otto, STAEHELI, Peter, KOCHS, Georg
Published in Journal of general virology (01.05.2012)
Published in Journal of general virology (01.05.2012)
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Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance gene
Grimm, Daniel, Staeheli, Peter, Hufbauer, Martin, Koerner, Iris, Martínez-Sobrido, Luis, Solórzano, Alicia, García-Sastre, Adolfo, Haller, Otto, Kochs, Georg
Published in Proceedings of the National Academy of Sciences - PNAS (17.04.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (17.04.2007)
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The Mx1 Gene Protects Mice against the Pandemic 1918 and Highly Lethal Human H5N1 Influenza Viruses
TUMPEY, Terrence M, SZRETTER, Kristy J, VAN HOEVEN, Neal, KATZ, Jacqueline M, KOCHS, Georg, HALLER, Otto, GARCIA-SASTRE, Adolfo, STAEHELI, Peter
Published in Journal of Virology (01.10.2007)
Published in Journal of Virology (01.10.2007)
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Inhibition of Beta Interferon Induction by Severe Acute Respiratory Syndrome Coronavirus Suggests a Two-Step Model for Activation of Interferon Regulatory Factor 3
SPIEGEL, Martin, PICHLMAIR, Andreas, MARTINEZ-SOBRIDO, Luis, CROS, Jerome, GARCIA-SASTRE, Adolfo, HALLER, Otto, WEBER, Friedemann
Published in Journal of Virology (01.02.2005)
Published in Journal of Virology (01.02.2005)
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Intranasal Administration of Alpha Interferon Reduces Seasonal Influenza A Virus Morbidity in Ferrets
KUGEL, Daniela, KOCHS, Georg, OBOJES, Karola, ROTH, Joachim, KOBINGER, Gary P, KOBASA, Darwyn, HALLER, Otto, STAEHELI, Peter, VON MESSLING, Veronika
Published in Journal of Virology (01.04.2009)
Published in Journal of Virology (01.04.2009)
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