Escape mutations circumvent a tradeoff between resistance to a beta-lactam and resistance to a beta-lactamase inhibitor
Russ, Dor, Glaser, Fabian, Shaer Tamar, Einat, Yelin, Idan, Baym, Michael, Kelsic, Eric D., Zampaloni, Claudia, Haldimann, Andreas, Kishony, Roy
Published in Nature communications (24.04.2020)
Published in Nature communications (24.04.2020)
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Nacubactam Enhances Meropenem Activity against Carbapenem-Resistant Klebsiella pneumoniae Producing KPC
Barnes, Melissa D, Taracila, Magdalena A, Good, Caryn E, Bajaksouzian, Saralee, Rojas, Laura J, van Duin, David, Kreiswirth, Barry N, Jacobs, Michael R, Haldimann, Andreas, Papp-Wallace, Krisztina M, Bonomo, Robert A
Published in Antimicrobial agents and chemotherapy (01.08.2019)
Published in Antimicrobial agents and chemotherapy (01.08.2019)
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Efficacy of Iclaprim against Wild-Type and Thymidine Kinase-Deficient Methicillin-Resistant Staphylococcus aureus Isolates in an In Vitro Fibrin Clot Model
ENTENZA, José M, HALDIMANN, Andreas, GIDDEY, Marlyse, LOCIURO, Sergio, HAWSER, Stephen, MOREILLON, Philippe
Published in Antimicrobial Agents and Chemotherapy (01.09.2009)
Published in Antimicrobial Agents and Chemotherapy (01.09.2009)
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Escherichia coli phnN, Encoding Ribose 1,5-Bisphosphokinase Activity (Phosphoribosyl Diphosphate Forming): Dual Role in Phosphonate Degradation and NAD Biosynthesis Pathways
Hove-Jensen, Bjarne, Rosenkrantz, Tina J, Haldimann, Andreas, Wanner, Barry L
Published in Journal of Bacteriology (01.05.2003)
Published in Journal of Bacteriology (01.05.2003)
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Journal Article
In vivo Characterization of the Type A and B Vancomycin-Resistant Enterococci (VRE) VanRS Two-Component Systems in Escherichia coli: A Nonpathogenic Model for Studying the VRE Signal Transduction Pathways
Silva, Jeffrey C., Haldimann, Andreas, Prahalad, Murali K., Walsh, Christopher T., Wanner, Barry L.
Published in Proceedings of the National Academy of Sciences - PNAS (29.09.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (29.09.1998)
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A novel antibiotic class targeting the lipopolysaccharide transporter
Zampaloni, Claudia, Mattei, Patrizio, Bleicher, Konrad, Winther, Lotte, Thäte, Claudia, Bucher, Christian, Adam, Jean-Michel, Alanine, Alexander, Amrein, Kurt E., Baidin, Vadim, Bieniossek, Christoph, Bissantz, Caterina, Boess, Franziska, Cantrill, Carina, Clairfeuille, Thomas, Dey, Fabian, Di Giorgio, Patrick, du Castel, Pauline, Dylus, David, Dzygiel, Pawel, Felici, Antonio, García-Alcalde, Fernando, Haldimann, Andreas, Leipner, Matthew, Leyn, Semen, Louvel, Séverine, Misson, Pauline, Osterman, Andrei, Pahil, Karanbir, Rigo, Sébastien, Schäublin, Adrian, Scharf, Sebastian, Schmitz, Petra, Stoll, Theodor, Trauner, Andrej, Zoffmann, Sannah, Kahne, Daniel, Young, John A. T., Lobritz, Michael A., Bradley, Kenneth A.
Published in Nature (London) (18.01.2024)
Published in Nature (London) (18.01.2024)
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A novel mechanism-based pharmacokinetic–pharmacodynamic (PKPD) model describing ceftazidime/avibactam efficacy against β-lactamase-producing Gram-negative bacteria
Kristoffersson, Anders N, Bissantz, Caterina, Okujava, Rusudan, Haldimann, Andreas, Walter, Isabelle, Shi, Tianlai, Zampaloni, Claudia, Nielsen, Elisabet I
Published in Journal of antimicrobial chemotherapy (01.02.2020)
Published in Journal of antimicrobial chemotherapy (01.02.2020)
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Journal Article
Altered Recognition Mutants of the Response Regulator PhoB: A New Genetic Strategy for Studying Protein--Protein Interactions
Haldimann, Andreas, Prahalad, Murali K., Fisher, Stewart L., Kim, Soo-Ki, Walsh, Christopher T., Wanner, Barry L.
Published in Proceedings of the National Academy of Sciences - PNAS (10.12.1996)
Published in Proceedings of the National Academy of Sciences - PNAS (10.12.1996)
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Journal Article
Author Correction: A novel antibiotic class targeting the lipopolysaccharide transporter
Zampaloni, Claudia, Mattei, Patrizio, Bleicher, Konrad, Winther, Lotte, Thäte, Claudia, Bucher, Christian, Adam, Jean-Michel, Alanine, Alexander, Amrein, Kurt E., Baidin, Vadim, Bieniossek, Christoph, Bissantz, Caterina, Boess, Franziska, Cantrill, Carina, Clairfeuille, Thomas, Dey, Fabian, Di Giorgio, Patrick, du Castel, Pauline, Dylus, David, Dzygiel, Pawel, Felici, Antonio, García-Alcalde, Fernando, Haldimann, Andreas, Leipner, Matthew, Leyn, Semen, Louvel, Séverine, Misson, Pauline, Osterman, Andrei, Pahil, Karanbir, Rigo, Sébastien, Schäublin, Adrian, Scharf, Sebastian, Schmitz, Petra, Stoll, Theodor, Trauner, Andrej, Zoffmann, Sannah, Kahne, Daniel, Young, John A. T., Lobritz, Michael A., Bradley, Kenneth A.
Published in Nature (London) (25.07.2024)
Published in Nature (London) (25.07.2024)
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Journal Article
Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity
Oefner, Christian, Bandera, Monica, Haldimann, Andreas, Laue, Heike, Schulz, Henk, Mukhija, Seema, Parisi, Sandro, Weiss, Laurent, Lociuro, Sergio, Dale, Glenn E.
Published in Journal of antimicrobial chemotherapy (01.04.2009)
Published in Journal of antimicrobial chemotherapy (01.04.2009)
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Journal Article
1359. Activity of Meropenem/Nacubactam Combination Against Gram-Negative Clinical Isolates: ROSCO Global Surveillance 2017
Okujava, Rusudan, Garcia-Alcalde, Fernando, Haldimann, Andreas, Zampaloni, Claudia, Morrissey, Ian, Magnet, Sophie, Kothari, Nimmi, Harding, Ian, Bradley, Kenneth
Published in Open forum infectious diseases (26.11.2018)
Published in Open forum infectious diseases (26.11.2018)
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Conditionally replicative and conjugative plasmids carrying lacZ alpha for cloning, mutagenesis, and allele replacement in bacteria
Metcalf, W W, Jiang, W, Daniels, L L, Kim, S K, Haldimann, A, Wanner, B L
Published in Plasmid (01.01.1996)
Published in Plasmid (01.01.1996)
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Journal Article
Transcriptional regulation of the Enterococcus faecium BM4147 vancomycin resistance gene cluster by the VanS-VanR two-component regulatory system in Escherichia coli K-12
Haldimann, A, Fisher, S L, Daniels, L L, Walsh, C T, Wanner, B L
Published in Journal of Bacteriology (01.09.1997)
Published in Journal of Bacteriology (01.09.1997)
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Journal Article
Sequence analysis and transcription of the apxI operon (hemolysin I) from Actinobacillus pleuropneumoniae
Frey, Joachim, Haldimann, Andreas, Nicolet, Jacques, Boffini, Andrea, Prentki, Pierre
Published in Gene (03.05.1994)
Published in Gene (03.05.1994)
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Transcriptional regulation of the Enterococcus faecium BM4147 vancomycin resistance gene cluster by the VanS-VanR two-component regulatory system in
Haldimann, Andreas, Fisher, Stewart L, Daniels, Larry L, Walsh, Christopher T, Wanner, Barry L
Published in Journal of bacteriology (01.09.1997)
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Published in Journal of bacteriology (01.09.1997)
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