Practical and Scalable Synthetic Method for Preparation of Dolutegravir Sodium: Improvement of a Synthetic Route for Large-Scale Synthesis
Aoyama, Yasunori, Hakogi, Toshikazu, Fukui, Yuki, Yamada, Daisuke, Ooyama, Takao, Nishino, Yutaka, Shinomoto, Shoji, Nagai, Masahiko, Miyake, Naoki, Taoda, Yoshiyuki, Yoshida, Hiroshi, Yasukata, Tatsuro
Published in Organic process research & development (19.04.2019)
Published in Organic process research & development (19.04.2019)
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Development of a One-Pot Asymmetric Azaelectrocyclization Protocol: Synthesis of Chiral 2,4-Disubstituted 1,2,5,6-Tetrahydropyridines
Kobayashi, Toyoharu, Nakashima, Miyuki, Hakogi, Toshikazu, Tanaka, Katsunori, Katsumura, Shigeo
Published in Organic letters (17.08.2006)
Published in Organic letters (17.08.2006)
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Process Optimization of Aldol-Type Reaction by Process Understanding Using in Situ IR
Fukui, Yuki, Oda, Shinichi, Suzuki, Hiroyuki, Hakogi, Toshikazu, Yamada, Daisuke, Takagi, Yohei, Aoyama, Yasunori, Kitamura, Hideyuki, Ogawa, Masayoshi, Kikuchi, Junko
Published in Organic process research & development (16.11.2012)
Published in Organic process research & development (16.11.2012)
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Cross metathesis route in sphingomyelin synthesis
Hasegawa, H, Yamamoto, T, Hatano, S, Hakogi, T, Katsumura, S
Published in Chemistry letters (01.12.2004)
Published in Chemistry letters (01.12.2004)
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Synthesis of fluorescence-Labeled sphingosine and sphingosine 1-phosphate; effective tools for sphingosine and sphingosine 1-phosphate behavior
Hakogi, Toshikazu, Shigenari, Toshihiko, Katsumura, Shigeo, Sano, Takamitsu, Kohno, Takayuki, Igarashi, Yasuyuki
Published in Bioorganic & medicinal chemistry letters (24.02.2003)
Published in Bioorganic & medicinal chemistry letters (24.02.2003)
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Stereoselective Synthesis of Baloxavir Marboxil Using Diastereoselective Cyclization and Photoredox Decarboxylation of l‑Serine
Okamoto, Kazuya, Ueno, Tatsuhiko, Hato, Yoshio, Kawaguchi, Yasunori, Hakogi, Toshikazu, Majima, Shohei, Ohara, Takafumi, Hagihara, Motoyuki, Tanimoto, Norihiko, Tsuritani, Takayuki
Published in Journal of organic chemistry (19.07.2024)
Published in Journal of organic chemistry (19.07.2024)
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Hybrid Modeling of an Active Pharmaceutical Ingredient Flow Synthesis in a Ring-Opening Reaction of an Epoxide with a Grignard Reagent
Kim, Junu, Hayashi, Yusuke, Badr, Sara, Okamoto, Kazuya, Hakogi, Toshikazu, Furukawa, Haruo, Yoshikawa, Satoshi, Nakanishi, Hayao, Sugiyama, Hirokazu
Published in Industrial & engineering chemistry research (01.11.2023)
Published in Industrial & engineering chemistry research (01.11.2023)
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Kinetic Study and Model-Based Design Space Determination for a Drug Substance Flow Synthesis Using an Amination Reaction via Nucleophilic Aromatic Substitution
Kim, Junu, Hayashi, Yusuke, Badr, Sara, Okamoto, Kazuya, Hakogi, Toshikazu, Furukawa, Haruo, Yoshikawa, Satoshi, Nakanishi, Hayao, Sugiyama, Hirokazu
Published in Organic process research & development (17.05.2024)
Published in Organic process research & development (17.05.2024)
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Mechanistic insights into amination via nucleophilic aromatic substitution
Kim, Junu, Hayashi, Yusuke, Badr, Sara, Okamoto, Kazuya, Hakogi, Toshikazu, Furukawa, Haruo, Yoshikawa, Satoshi, Nakanishi, Hayao, Sugiyama, Hirokazu
Published in Reaction chemistry & engineering (25.07.2023)
Published in Reaction chemistry & engineering (25.07.2023)
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Journal Article
Mechanistic insights into amination nucleophilic aromatic substitution
Kim, Junu, Hayashi, Yusuke, Badr, Sara, Okamoto, Kazuya, Hakogi, Toshikazu, Furukawa, Haruo, Yoshikawa, Satoshi, Nakanishi, Hayao, Sugiyama, Hirokazu
Published in Reaction chemistry & engineering (25.07.2023)
Published in Reaction chemistry & engineering (25.07.2023)
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Year of Publication 10.06.2020
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Year of Publication 10.06.2020
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METHOD FOR STEREOSELECTIVELY PRODUCING SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVE
HAKOGI, Toshikazu, HATO, Yoshio, MAJIMA, Shohei, OKAMOTO, Kazuya, UENO, Tatsuhiko
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Year of Publication 11.04.2019
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WEATHERHEAD JASON GORDON, AOYAMA YASUNORI, JOHNS BRIAN ALVIN, HAKOGI TOSHIKAZU
Year of Publication 09.12.2016
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Year of Publication 09.12.2016
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WEATHERHEAD JASON GORDON, AOYAMA YASUNORI, JOHNS BRIAN ALVIN, HAKOGI TOSHIKAZU
Year of Publication 09.12.2016
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Year of Publication 09.12.2016
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