DNA-PK inhibitor peposertib enhances p53-dependent cytotoxicity of DNA double-strand break inducing therapy in acute leukemia
Haines, Eric, Nishida, Yuki, Carr, Michael I., Montoya, Rafael Heinz, Ostermann, Lauren B., Zhang, Weiguo, Zenke, Frank T., Blaukat, Andree, Andreeff, Michael, Vassilev, Lyubomir T.
Published in Scientific reports (09.06.2021)
Published in Scientific reports (09.06.2021)
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An anillin-Ect2 complex stabilizes central spindle microtubules at the cortex during cytokinesis
Frenette, Paul, Haines, Eric, Loloyan, Michael, Kinal, Mena, Pakarian, Paknoosh, Piekny, Alisa
Published in PloS one (13.04.2012)
Published in PloS one (13.04.2012)
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BT7480, a novel fully synthetic Bicycle tumor-targeted immune cell agonist™ (Bicycle TICA™) induces tumor localized CD137 agonism
Hurov, Kristen, Lahdenranta, Johanna, Upadhyaya, Punit, Haines, Eric, Cohen, Heather, Repash, Elizabeth, Kanakia, Drasti, Ma, Jun, Kristensson, Julia, You, Fanglei, Campbell, Carly, Witty, David, Kelly, Mike, Blakemore, Stephen, Jeffrey, Phil, McDonnell, Kevin, Brandish, Philip, Keen, Nicholas
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist
Upadhyaya, Punit, Lahdenranta, Johanna, Hurov, Kristen, Battula, Sailaja, Dods, Rachel, Haines, Eric, Kleyman, Marianna, Kristensson, Julia, Kublin, Jessica, Lani, Rachid, Ma, Jun, Mudd, Gemma, Repash, Elizabeth, Van Rietschoten, Katerine, Stephen, Tom, You, Fanglei, Harrison, Helen, Chen, Liuhong, McDonnell, Kevin, Brandish, Philip, Keen, Nicholas
Published in Journal for immunotherapy of cancer (01.01.2021)
Published in Journal for immunotherapy of cancer (01.01.2021)
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Journal Article
Smad Signaling Antagonizes STAT5-mediated Gene Transcription and Mammary Epithelial Cell Differentiation
Cocolakis, Eftihia, Dai, Meiou, Drevet, Loren, Ho, Joanne, Haines, Eric, Ali, Suhad, Lebrun, Jean-Jacques
Published in The Journal of biological chemistry (18.01.2008)
Published in The Journal of biological chemistry (18.01.2008)
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700 EphA2/CD137 Bicycle tumor-targeted immune cell agonists (TICAsTM) induce tumor regressions, immunogenic memory, and reprogramming of the tumor immune microenvironment
Hurov, Kristen, lahdenranta, Johanna, Mudd, Gemma, Upadhyaya, Punit, Repash, Elizabeth, Ma, Jun, Kristensson, Julia, Kleyman, Marianna, Kublin, Jessica, Chen, Liuhong, Haines, Eric, Battula, Sailaja, McDonnell, Kevin, Brandish, Philip, Keen, Nicholas
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Tyrosine Phosphorylation of Grb2: Role in Prolactin/Epidermal Growth Factor Cross Talk in Mammary Epithelial Cell Growth and Differentiation
Haines, Eric, Minoo, Parham, Feng, Zhenqian, Resalatpanah, Nazila, Nie, Xin-Min, Campiglio, Manuela, Alvarez, Laura, Cocolakis, Eftihia, Ridha, Mohammed, Di Fulvio, Mauricio, Gomez-Cambronero, Julian, Lebrun, Jean-Jacques, Ali, Suhad
Published in Molecular and Cellular Biology (01.05.2009)
Published in Molecular and Cellular Biology (01.05.2009)
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Correction: Smad signaling antagonizes STAT5-mediated gene transcription and mammary epithelial cell differentiation
Cocolakis, Eftihia, Dai, Meiou, Drevet, Loren, Ho, Joanne, Haines, Eric, Ali, Suhad, Lebrun, Jean-Jacques
Published in The Journal of biological chemistry (01.10.2023)
Published in The Journal of biological chemistry (01.10.2023)
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Journal Article
CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation
Deng, Jiehui, Wang, Eric S, Jenkins, Russell W, Li, Shuai, Dries, Ruben, Yates, Kathleen, Chhabra, Sandeep, Huang, Wei, Liu, Hongye, Aref, Amir R, Ivanova, Elena, Paweletz, Cloud P, Bowden, Michaela, Zhou, Chensheng W, Herter-Sprie, Grit S, Sorrentino, Jessica A, Bisi, John E, Lizotte, Patrick H, Merlino, Ashley A, Quinn, Max M, Bufe, Lauren E, Yang, Annan, Zhang, Yanxi, Zhang, Hua, Gao, Peng, Chen, Ting, Cavanaugh, Megan E, Rode, Amanda J, Haines, Eric, Roberts, Patrick J, Strum, Jay C, Richards, William G, Lorch, Jochen H, Parangi, Sareh, Gunda, Viswanath, Boland, Genevieve M, Bueno, Raphael, Palakurthi, Sangeetha, Freeman, Gordon J, Ritz, Jerome, Haining, W Nicholas, Sharpless, Norman E, Arthanari, Haribabu, Shapiro, Geoffrey I, Barbie, David A, Gray, Nathanael S, Wong, Kwok-Kin
Published in Cancer discovery (01.02.2018)
Published in Cancer discovery (01.02.2018)
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BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors
Rigby, Michael, Bennett, Gavin, Chen, Liuhong, Mudd, Gemma E, Harrison, Helen, Beswick, Paul J, Van Rietschoten, Katerine, Watcham, Sophie M, Scott, Heather S, Brown, Amy N, Park, Peter U, Campbell, Carly, Haines, Eric, Lahdenranta, Johanna, Skynner, Michael J, Jeffrey, Phil, Keen, Nicholas, Lee, Kevin
Published in Molecular cancer therapeutics (02.12.2022)
Published in Molecular cancer therapeutics (02.12.2022)
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Abstract 1728: Nectin-4-dependent immune cell stimulation and anti-tumor efficacy by BT7480, a Nectin-4/CD137 Bicycle ®tumor-targeted immune cell agonist (TICA™)
Hurov, Kristen, Lahdenranta, Johanna, Upadhyaya, Punit, Kanakia, Drasti, Repash, Elizabeth, You, Fanglei, Ma, Jun, Haines, Eric, Cohen, Heather, McDonnell, Kevin, Brandish, Philip E., Jeffrey, Phil, Keen, Nicholas
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 1724: Microinjection of Nectin-4/CD137 tumor-targeted immune cell agonist (TICA™) activates the local tumor microenvironment
Lahdenranta, Johanna, Blakemore, Stephen J., Hurov, Kristen, Grenley, Marc O., Upadhyaya, Punit, Campbell, Carly, Repash, Elizabeth, Haines, Eric, Brandish, Philip E., Klinghoffer, Richard A., Keen, Nicholas
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 4830: Selective DNA-PK inhibitor, M3814, boosts p53 apoptotic response to DNA double strand breaks and effectively kills acute leukemia cells: Implications for AML therapy
Haines, Eric, Zimmermann, Astrid, Zenke, Frank, Blaukat, Andree, Vassilev, Lyubomir T.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract 5552: BT7480, a novel fully synthetic tumor-targeted immune cell agonist (TICATM) induces tumor localized 4-1BB agonism
Hurov, Kristen, Upadhyaya, Punit, Lahdenranta, Johanna, Kublin, Jessica, Ma, Jun, Repash, Elizabeth, Kleyman, Marianna, Kristensson, Julia, Chen, Liuhong, Haines, Eric, Battula, Sailaja, McDonnell, Kevin, Keen, Nicholas
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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