Assessing spatial pattern separation in rodents using the object pattern separation task
van Goethem, Nick P, van Hagen, Britt T J, Prickaerts, Jos
Published in Nature protocols (01.08.2018)
Published in Nature protocols (01.08.2018)
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Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer's disease
Ricciarelli, Roberta, Brullo, Chiara, Prickaerts, Jos, Arancio, Ottavio, Villa, Carla, Rebosio, Claudia, Calcagno, Elisa, Balbi, Matilde, van Hagen, Britt T J, Argyrousi, Elentina K, Zhang, Hong, Pronzato, Maria Adelaide, Bruno, Olga, Fedele, Ernesto
Published in Scientific reports (12.04.2017)
Published in Scientific reports (12.04.2017)
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Pro-cognitive effect of upregulating cyclic guanosine monophosphate signalling during memory acquisition or early consolidation is mediated by increased AMPA receptor trafficking
Argyrousi, Elentina K, Heckman, Pim RA, van Hagen, Britt TJ, Muysers, Hannah, van Goethem, Nick P, Prickaerts, Jos
Published in Journal of psychopharmacology (Oxford) (01.01.2020)
Published in Journal of psychopharmacology (Oxford) (01.01.2020)
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Biased 5-HT1A receptor agonists F13714 and NLX-101 differentially affect pattern separation and neuronal plasticity in rats after acute and chronic treatment
van Hagen, Britt T.J., van Goethem, Nick P., Nelissen, Ellis, Paes, Dean, Koymans, Karin, van Hoof, Scott, Schreiber, Rudy, Varney, Mark, Newman-Tancredi, Adrian, Prickaerts, Jos
Published in Molecular and cellular neuroscience (01.05.2022)
Published in Molecular and cellular neuroscience (01.05.2022)
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Soluble guanylate cyclase stimulator riociguat improves spatial memory in mice via peripheral mechanisms
Nelissen, Ellis, van Hagen, Britt T.J., Argyrousi, Elentina K., van Goethem, Nick P., Heckman, Pim R.A., Paes, Dean, Mulder-Jongen, Danielle A.J., Ramaekers, Johannes G., Blokland, Arjan, Schmidt, Harald H.H.W., Prickaerts, Jos
Published in Neuroscience letters (25.09.2022)
Published in Neuroscience letters (25.09.2022)
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Validation of the xylazine/ketamine anesthesia test as a predictor of the emetic potential of pharmacological compounds in rats
Nelissen, Ellis, van Goethem, Nick P., Bonassoli, Vivian T., Heckman, Pim R.A., van Hagen, Britt T.J., Suay, Dila, Wouters, Caroline, Prickaerts, Jos
Published in Neuroscience letters (23.04.2019)
Published in Neuroscience letters (23.04.2019)
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2-Iminopyrrolidines as Potent and Selective Inhibitors of Human Inducible Nitric Oxide Synthase
Hagen, Timothy J, Bergmanis, Arija A, Kramer, Steven W, Fok, Kam F, Schmelzer, Albert E, Pitzele, Barnett S, Swenton, Lydia, Jerome, Gina M, Kornmeier, Christine M, Moore, William M, Branson, Linda F, Connor, Jane R, Manning, Pamela T, Currie, Mark G, Hallinan, E. Ann
Published in Journal of medicinal chemistry (10.09.1998)
Published in Journal of medicinal chemistry (10.09.1998)
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Substituted 2-Iminopiperidines as Inhibitors of Human Nitric Oxide Synthase Isoforms
Webber, R. Keith, Metz, Suzanne, Moore, William M, Connor, Jane R, Currie, Mark G, Fok, Kam F, Hagen, Timothy J, Hansen, Donald W, Jerome, Gina M, Manning, Pamela T, Pitzele, Barnett S, Toth, Mihaly V, Trivedi, Mahima, Zupec, Mark E, Tjoeng, F. Siong
Published in Journal of medicinal chemistry (01.01.1998)
Published in Journal of medicinal chemistry (01.01.1998)
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New insights into selective PDE4D inhibitors: 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-dimethylmorpholino)-2-oxoethyl) oxime (GEBR-7b) structural development and promising activities to restore memory impairment
Brullo, Chiara, Ricciarelli, Roberta, Prickaerts, Jos, Arancio, Ottavio, Massa, Matteo, Rotolo, Chiara, Romussi, Alessia, Rebosio, Claudia, Marengo, Barbara, Pronzato, Maria Adelaide, van Hagen, Britt T.J., van Goethem, Nick P., D'Ursi, Pasqualina, Orro, Alessandro, Milanesi, Luciano, Guariento, Sara, Cichero, Elena, Fossa, Paola, Fedele, Ernesto, Bruno, Olga
Published in European journal of medicinal chemistry (29.11.2016)
Published in European journal of medicinal chemistry (29.11.2016)
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Design of a rotating facility for extracorporal treatment of an explanted liver with disseminated metastases by boron neutron capture therapy with an epithermal neutron beam
Nievaart, V A, Moss, R L, Kloosterman, J L, van der Hagen, T H J J, van Dam, H, Wittig, A, Malago, M, Sauerwein, W
Published in Radiation research (01.07.2006)
Published in Radiation research (01.07.2006)
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Synthetic and computer-assisted analyses of the pharmacophore for the benzodiazepine receptor inverse agonist site
Allen, Michael S, Tan, Yun C, Trudell, Mark L, Narayanan, Kris, Schindler, Liesl R, Martin, Michael J, Schultz, Christopher, Hagen, Timothy J, Koehler, Konrad F
Published in Journal of medicinal chemistry (01.09.1990)
Published in Journal of medicinal chemistry (01.09.1990)
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Epigenetic modifications in mouse cerebellar Purkinje cells: effects of aging, caloric restriction, and overexpression of superoxide dismutase 1 on 5-methylcytosine and 5-hydroxymethylcytosine
Lardenoije, Roy, van den Hove, Daniël L.A, Vaessen, Thomas S.J, Iatrou, Artemis, Meuwissen, Koen P.V, van Hagen, Britt T.J, Kenis, Gunter, Steinbusch, Harry W.M, Schmitz, Christoph, Rutten, Bart P.F
Published in Neurobiology of aging (01.11.2015)
Published in Neurobiology of aging (01.11.2015)
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Application of adjoint Monte Carlo to accelerate simulations of mono-directional beams in treatment planning for boron neutron capture therapy
Nievaart, V A, Légràdy, D, Moss, R L, Kloosterman, J L, van der Hagen, T H J J, van Dam, H
Published in Medical physics (Lancaster) (01.04.2007)
Published in Medical physics (Lancaster) (01.04.2007)
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Predictive binding of .beta.-carboline inverse agonists and antagonists via the CoMFA/GOLPE approach
Allen, Michael S, LaLoggia, Anthony J, Dorn, Linda J, Martin, Michael J, Costantino, Gabriele, Hagen, Timothy J, Koehler, Konrad F, Skolnick, Phil, Cook, James M
Published in Journal of medicinal chemistry (01.10.1992)
Published in Journal of medicinal chemistry (01.10.1992)
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