Managing the sequence-specificity of antisense oligonucleotides in drug discovery
Hagedorn, Peter H, Hansen, Bo R, Koch, Troels, Lindow, Morten
Published in Nucleic acids research (17.03.2017)
Published in Nucleic acids research (17.03.2017)
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Journal Article
Locked nucleic acid: modality, diversity, and drug discovery
Hagedorn, Peter H., Persson, Robert, Funder, Erik D., Albæk, Nanna, Diemer, Sanna L., Hansen, Dennis J., Møller, Marianne R., Papargyri, Natalia, Christiansen, Helle, Hansen, Bo R., Hansen, Henrik F., Jensen, Mads A., Koch, Troels
Published in Drug discovery today (01.01.2018)
Published in Drug discovery today (01.01.2018)
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Journal Article
IL-1β production through the NLRP3 inflammasome by hepatic macrophages links hepatitis C virus infection with liver inflammation and disease
Negash, Amina A, Ramos, Hilario J, Crochet, Nanette, Lau, Daryl T Y, Doehle, Brian, Papic, Neven, Delker, Don A, Jo, Juandy, Bertoletti, Antonio, Hagedorn, Curt H, Gale, Jr, Michael
Published in PLoS pathogens (01.04.2013)
Published in PLoS pathogens (01.04.2013)
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Journal Article
Long Noncoding RNA Expression during Human B-Cell Development
Petri, Andreas, Dybkær, Karen, Bøgsted, Martin, Thrue, Charlotte Albæk, Hagedorn, Peter H, Schmitz, Alexander, Bødker, Julie Støve, Johnsen, Hans Erik, Kauppinen, Sakari
Published in PloS one (22.09.2015)
Published in PloS one (22.09.2015)
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Journal Article
Bcl2 is a critical regulator of bile acid homeostasis by dictating Shp and lncRNA H19 function
Zhang, Yuxia, Liu, Chune, Barbier, Olivier, Smalling, Rana, Tsuchiya, Hiroyuki, Lee, Sangmin, Delker, Don, Zou, An, Hagedorn, Curt H., Wang, Li
Published in Scientific reports (03.02.2016)
Published in Scientific reports (03.02.2016)
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Journal Article
Interferon lambda 4 expression is suppressed by the host during viral infection
Hong, MeeAe, Schwerk, Johannes, Lim, Chrissie, Kell, Alison, Jarret, Abigail, Pangallo, Joseph, Loo, Yueh-Ming, Liu, Shuanghu, Hagedorn, Curt H, Gale, Jr, Michael, Savan, Ram
Published in The Journal of experimental medicine (14.11.2016)
Published in The Journal of experimental medicine (14.11.2016)
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Journal Article
RNA sequencing of sessile serrated colon polyps identifies differentially expressed genes and immunohistochemical markers
Delker, Don A, McGettigan, Brett M, Kanth, Priyanka, Pop, Stelian, Neklason, Deborah W, Bronner, Mary P, Burt, Randall W, Hagedorn, Curt H
Published in PloS one (12.02.2014)
Published in PloS one (12.02.2014)
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Journal Article
A Sensitive In Vitro Approach to Assess the Hybridization-Dependent Toxic Potential of High Affinity Gapmer Oligonucleotides
Dieckmann, Andreas, Hagedorn, Peter H., Burki, Yvonne, Brügmann, Christine, Berrera, Marco, Ebeling, Martin, Singer, Thomas, Schuler, Franz
Published in Molecular therapy. Nucleic acids (02.03.2018)
Published in Molecular therapy. Nucleic acids (02.03.2018)
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Journal Article
Chemical Diversity of Locked Nucleic Acid-Modified Antisense Oligonucleotides Allows Optimization of Pharmaceutical Properties
Papargyri, Natalia, Pontoppidan, Malene, Andersen, Mikael R., Koch, Troels, Hagedorn, Peter H.
Published in Molecular therapy. Nucleic acids (06.03.2020)
Published in Molecular therapy. Nucleic acids (06.03.2020)
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Journal Article
Human RNA polymerase III transcriptomes and relationships to Pol II promoter chromatin and enhancer-binding factors
Alla, Ravi K, Chandler, Katherine J, Oler, Andrew J, Hagedorn, Curt H, Cassiday, Patrick A, Cairns, Bradley R, Hollenhorst, Peter C, Graves, Barbara J, Wong, Alexander, Nelson, Cassie A, Roberts, Douglas N
Published in Nature structural & molecular biology (01.05.2010)
Published in Nature structural & molecular biology (01.05.2010)
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Journal Article
Divalent Metal Transporter 1 Regulates Iron-Mediated ROS and Pancreatic β Cell Fate in Response to Cytokines
Hansen, Jakob Bondo, Tonnesen, Morten Fog, Madsen, Andreas Nygaard, Hagedorn, Peter H., Friberg, Josefine, Grunnet, Lars Groth, Heller, R. Scott, Nielsen, Anja Østergren, Størling, Joachim, Baeyens, Luc, Anker-Kitai, Leeat, Qvortrup, Klaus, Bouwens, Luc, Efrat, Shimon, Aalund, Mogens, Andrews, Nancy C., Billestrup, Nils, Karlsen, Allan E., Holst, Birgitte, Pociot, Flemming, Mandrup-Poulsen, Thomas
Published in Cell metabolism (03.10.2012)
Published in Cell metabolism (03.10.2012)
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Journal Article
Impact of Hepatitis C Seropositivity on the Risk of Coronary Heart Disease Events
Pothineni, Naga Venkata Krishna Chand, MD, Delongchamp, Robert, PhD, Vallurupalli, Srikanth, MD, Ding, Zufeng, PhD, Dai, Yao, PhD, Hagedorn, Curt H., MD, Mehta, Jawahar L., MD, PhD
Published in The American journal of cardiology (15.12.2014)
Published in The American journal of cardiology (15.12.2014)
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Journal Article
Activation of PERK-Nrf2 oncogenic signaling promotes Mdm2-mediated Rb degradation in persistently infected HCV culture
Aydin, Yucel, Chedid, Milad, Chava, Srinivas, Danielle Williams, Donkita, Liu, Shuanghu, Hagedorn, Curt H, Sumitran-Holgersson, Suchitra, Reiss, Krzysztof, Moroz, Krzysztof, Lu, Hua, Balart, Luis A, Dash, Srikanta
Published in Scientific reports (23.08.2017)
Published in Scientific reports (23.08.2017)
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Journal Article
Viral and Therapeutic Control of IFN-β Promoter Stimulator 1 during Hepatitis C Virus Infection
Loo, Yueh-Ming, Owen, David M., Li, Kui, Erickson, Andrea K., Johnson, Cynthia L., Fish, Penny M., Carney, D. Spencer, Wang, Ting, Ishida, Hisashi, Yoneyama, Mitsutoshi, Fujita, Takashi, Saito, Takeshi, Lee, William M., Hagedorn, Curt H., Lau, Daryl T.-Y., Weinman, Steven A., Lemon, Stanley M., Gale, Michael
Published in Proceedings of the National Academy of Sciences - PNAS (11.04.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (11.04.2006)
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Journal Article
Genome-wide transcriptome analysis identifies novel gene signatures implicated in human chronic liver disease
Smalling, Rana L, Delker, Don A, Zhang, Yuxia, Nieto, Natalia, McGuiness, Michael S, Liu, Shuanghu, Friedman, Scott L, Hagedorn, Curt H, Wang, Li
Published in American journal of physiology: Gastrointestinal and liver physiology (01.09.2013)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.09.2013)
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Journal Article
Transcriptional regulation by an NAC (NAM-ATAF1,2-CUC2) transcription factor attenuates ABA signalling for efficient basal defence towards Blumeria graminis f. sp. hordei in Arabidopsis
Jensen, Michael K, Hagedorn, Peter H, de Torres-Zabala, Marta, Grant, Murray R, Rung, Jesper H, Collinge, David B, Lyngkjaer, Michael F
Published in The Plant journal : for cell and molecular biology (01.12.2008)
Published in The Plant journal : for cell and molecular biology (01.12.2008)
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Journal Article
Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: a randomized placebo-controlled, double-blind trial
Meyskens, Jr, Frank L, McLaren, Christine E, Pelot, Daniel, Fujikawa-Brooks, Sharon, Carpenter, Philip M, Hawk, Ernest, Kelloff, Gary, Lawson, Michael J, Kidao, Jayashri, McCracken, John, Albers, C Gregory, Ahnen, Dennis J, Turgeon, D Kim, Goldschmid, Steven, Lance, Peter, Hagedorn, Curt H, Gillen, Daniel L, Gerner, Eugene W
Published in Cancer prevention research (Philadelphia, Pa.) (01.06.2008)
Published in Cancer prevention research (Philadelphia, Pa.) (01.06.2008)
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