Drug repositioning for Alzheimer's disease
Corbett, Anne, Pickett, James, Burns, Alistair, Corcoran, Jonathan, Dunnett, Stephen B., Edison, Paul, Hagan, Jim J., Holmes, Clive, Jones, Emma, Katona, Cornelius, Kearns, Ian, Kehoe, Patrick, Mudher, Amrit, Passmore, Anthony, Shepherd, Nicola, Walsh, Frank, Ballard, Clive
Published in Nature reviews. Drug discovery (01.11.2012)
Published in Nature reviews. Drug discovery (01.11.2012)
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Altered M1 Muscarinic Acetylcholine Receptor (CHRM I)-Gαq/11 Coupling in a Schizophrenia Endophenotype
SALAH-UDDIN, Hasib, SCARR, Elizabeth, PAVEY, Geoffrey, HARRIS, Kriss, HAGAN, Jim, DEAN, Brian, CHALLISS, R. A.john, WATSON, Jeannette M
Published in Neuropsychopharmacology (New York, N.Y.) (01.08.2009)
Published in Neuropsychopharmacology (New York, N.Y.) (01.08.2009)
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Transcription and pathway analysis of the superior temporal cortex and anterior prefrontal cortex in schizophrenia
Barnes, Michael R., Huxley-Jones, Julie, Maycox, Peter R., Lennon, Mark, Thornber, Amy, Kelly, Fiona, Bates, Stewart, Taylor, Adam, Reid, Juliet, Jones, Neil, Schroeder, Jörn, Scorer, Carol A., Davies, Ceri, Hagan, Jim J., Kew, James N.C., Angelinetta, Claire, Akbar, Tariq, Hirsch, Steven, Mortimer, Ann M., Barnes, Thomas R.E., de Belleroche, Jackie
Published in Journal of neuroscience research (01.08.2011)
Published in Journal of neuroscience research (01.08.2011)
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Long-lasting changes in behavioural and neuroendocrine indices in the rat following neonatal maternal separation: Gender-dependent effects
Slotten, Helge A., Kalinichev, Mikhail, Hagan, Jim J., Marsden, Charles A., Fone, Kevin C.F.
Published in Brain research (30.06.2006)
Published in Brain research (30.06.2006)
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5-HT7 receptors
Thomas, David R, Hagan, Jim J
Published in Current drug targets. CNS & neurological disorders (01.02.2004)
Published in Current drug targets. CNS & neurological disorders (01.02.2004)
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Orexin A Activates Locus Coeruleus Cell Firing and Increases Arousal in the Rat
Hagan, Jim J., Leslie, Ron A., Patel, Sara, Evans, Martyn L., Wattam, Trevor A., Holmes, Steve, Benham, Christopher D., Taylor, Stephen G., Routledge, Carol, Hemmati, Panida, Munton, Richard P., Ashmeade, Tracey E., Shah, Ajit S., Hatcher, Jonathan P., Hatcher, Paula D., Declan N. C. Jones, Smith, Martin I., Piper, David C., Hunter, A. Jackie, Porter, Rod A., Upton, Neil
Published in Proceedings of the National Academy of Sciences - PNAS (14.09.1999)
Published in Proceedings of the National Academy of Sciences - PNAS (14.09.1999)
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Selective antagonism at dopamine D3 receptors prevents nicotine-triggered relapse to nicotine-seeking behavior
ANDREOLI, Michela, TESSARI, Michela, PILLA, Maria, VALERIO, Enzo, HAGAN, Jim J, HEIDBREDER, Christian A
Published in Neuropsychopharmacology (New York, N.Y.) (01.07.2003)
Published in Neuropsychopharmacology (New York, N.Y.) (01.07.2003)
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Dopamine D3 Receptor Antagonism Inhibits Cocaine-Seeking and Cocaine-Enhanced Brain Reward in Rats
Vorel, Stanislav R, Ashby, Charles R., Jr, Paul, Mousumi, Liu, Xinhe, Hayes, Robert, Hagan, Jim J, Middlemiss, Derek N, Stemp, Geoffrey, Gardner, Eliot L
Published in The Journal of neuroscience (01.11.2002)
Published in The Journal of neuroscience (01.11.2002)
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Behavioural and cognitive abnormalities in an imprinting centre deletion mouse model for Prader-Willi syndrome
Relkovic, Dinko, Doe, Christine M., Humby, Trevor, Johnstone, Karen A., Resnick, James L., Holland, Anthony J., Hagan, Jim J., Wilkinson, Lawrence S., Isles, Anthony R.
Published in The European journal of neuroscience (01.01.2010)
Published in The European journal of neuroscience (01.01.2010)
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Blockade of mesolimbic dopamine D3 receptors inhibits stress-induced reinstatement of cocaine-seeking in rats
XI, Zheng-Xiong, GILBERT, Jeremy, CAMPOS, Arlene C, KLINE, Nicole, ASHBY, Charles R, HAGAN, Jim J, HEIDBREDER, Christian A, GARDNER, Eliot L
Published in Psychopharmacologia (01.10.2004)
Published in Psychopharmacologia (01.10.2004)
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5-HT6 receptor antagonists improve performance in an attentional set shifting task in rats
HATCHER, Paula D, BROWN, Verity J, TAIT, David S, BATE, Simon, OVEREND, Philip, HAGAN, Jim J, JONES, Declan N. C
Published in Psychopharmacologia (01.09.2005)
Published in Psychopharmacologia (01.09.2005)
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SB-649915-B, a novel 5-HT1A/B autoreceptor antagonist and serotonin reuptake inhibitor, is anxiolytic and displays fast onset activity in the rat high light social interaction test
Starr, Kathryn R, Price, Gary W, Watson, Jeannette M, Atkinson, Peter J, Arban, Roberto, Melotto, Sergio, Dawson, Lee A, Hagan, Jim J, Upton, Neil, Duxon, Mark S
Published in Neuropsychopharmacology (New York, N.Y.) (01.10.2007)
Published in Neuropsychopharmacology (New York, N.Y.) (01.10.2007)
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The selective 5-HT6 receptor antagonists SB-271046 and SB-399885 potentiate NCAM PSA immunolabeling of dentate granule cells, but not neurogenesis, in the hippocampal formation of mature Wistar rats
Foley, Andrew G, Hirst, Warren D, Gallagher, Helen C, Barry, Claire, Hagan, Jim J, Upton, Neil, Walsh, Frank S, Hunter, A Jackie, Regan, Ciaran M
Published in Neuropharmacology (01.06.2008)
Published in Neuropharmacology (01.06.2008)
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Characterization of SB‐269970‐A, a selective 5‐HT7 receptor antagonist
Hagan, Jim J, Price, Gary W, Jeffrey, Phillip, Deeks, Nigel J, Stean, Tania, Piper, David, Smith, Martin I, Upton, Neil, Medhurst, Andrew D, Middlemiss, Derek N, Riley, Graham J, Lovell, Peter J, Bromidge, Steven M, Thomas, David R
Published in British journal of pharmacology (01.06.2000)
Published in British journal of pharmacology (01.06.2000)
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The 5-HT6 receptor antagonist SB-271046 reverses scopolamine-disrupted consolidation of a passive avoidance task and ameliorates spatial task deficits in aged rats
FOLEY, Andrew G, MURPHY, Keith J, HIRST, Warren D, GALLAGHER, Helen C, HAGAN, Jim J, UPTON, Neil, WALSH, Frank S, REGAN, Ciaran M
Published in Neuropsychopharmacology (New York, N.Y.) (01.01.2004)
Published in Neuropsychopharmacology (New York, N.Y.) (01.01.2004)
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Fluoxetine administration modulates the cytoskeletal microtubular system in the rat hippocampus
Bianchi, Massimiliano, Shah, Ajit J., Fone, Kevin C.F., Atkins, Alan R., Dawson, Lee A., Heidbreder, Christian A., Hows, Mark E., Hagan, Jim J., Marsden, Charles A.
Published in Synapse (New York, N.Y.) (01.04.2009)
Published in Synapse (New York, N.Y.) (01.04.2009)
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The role of central dopamine D3 receptors in drug addiction : a review of pharmacological evidence
HEIDBREDER, Christian A, GARDNER, Eliot L, XI, Zheng-Xiong, THANOS, Panayotis K, MUGNAINI, Manolo, HAGAN, Jim J, ASHBY, Charles R
Published in Brain Research Reviews (01.07.2005)
Published in Brain Research Reviews (01.07.2005)
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