Synthesis and Biological Evaluation of 2- and 3-Aminobenzo[b]thiophene Derivatives as Antimitotic Agents and Inhibitors of Tubulin Polymerization
Romagnoli, Romeo, Baraldi, Pier Giovanni, Carrion, Maria Dora, Cara, Carlota Lopez, Preti, Delia, Fruttarolo, Francesca, Pavani, Maria Giovanna, Tabrizi, Mojgan Aghazadeh, Tolomeo, Manlio, Grimaudo, Stefania, Di Cristina, Antonella, Balzarini, Jan, Hadfield, John A, Brancale, Andrea, Hamel, Ernest
Published in Journal of medicinal chemistry (03.05.2007)
Published in Journal of medicinal chemistry (03.05.2007)
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Novel Syntheses of Cis and Trans Isomers of Combretastatin A-4
Gaukroger, Keira, Hadfield, John A, Hepworth, Lucy A, Lawrence, Nicholas J, McGown, Alan T
Published in Journal of organic chemistry (30.11.2001)
Published in Journal of organic chemistry (30.11.2001)
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Tubulin-binding dibenz[c,e]oxepines: Part 2.(1) Structural variation and biological evaluation as tumour vasculature disrupting agents
Rossington, Steven B., Hadfield, John A., Shnyder, Steven D., Wallace, Timothy W., Williams, Kaye J.
Published in Bioorganic & medicinal chemistry (01.03.2017)
Published in Bioorganic & medicinal chemistry (01.03.2017)
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Novel cyanocombretastatins as potent tubulin polymerisation inhibitors
Jalily, Pouria H., Hadfield, John A., Hirst, Nicholas, Rossington, Steven B.
Published in Bioorganic & medicinal chemistry letters (01.11.2012)
Published in Bioorganic & medicinal chemistry letters (01.11.2012)
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Three-dimensional imaging and uptake of the anticancer drug combretastatin in cell spheroids and photoisomerization in gels with multiphoton excitation
Scherer, Kathrin M, Bisby, Roger H, Botchway, Stanley W, Hadfield, John A, Haycock, John W, Parker, Anthony W
Published in Journal of biomedical optics (01.07.2015)
Published in Journal of biomedical optics (01.07.2015)
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Tubulin as a target for anticancer drugs: Agents which interact with the mitotic spindle
Jordan, Allan, Hadfield, John A., Lawrence, Nicholas J., McGown, Alan T.
Published in Medicinal research reviews (01.07.1998)
Published in Medicinal research reviews (01.07.1998)
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Potent antimitotic and cell growth inhibitory properties of substituted chalcones
Ducki, Sylvie, Forrest, Richard, Hadfield, John A., Kendall, Alex, Lawrence, Nicholas J., McGown, Alan T., Rennison, David
Published in Bioorganic & medicinal chemistry letters (05.05.1998)
Published in Bioorganic & medicinal chemistry letters (05.05.1998)
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Time-resolved nanosecond fluorescence lifetime imaging and picosecond infrared spectroscopy of combretastatin A-4 in solution and in cellular systems
Bisby, Roger H, Botchway, Stanley W, Greetham, Greg M, Hadfield, John A, McGown, Alan T, Parker, Anthony W, Scherer, Kathrin M, Towrie, Mike
Published in Measurement science & technology (01.08.2012)
Published in Measurement science & technology (01.08.2012)
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Spectroscopy and fluorescence lifetime imaging in live cells of a cyano-substituted combretastatin
Scherer, Kathrin M., Bisby, Roger H., Botchway, Stanley W., Greetham, Greg M., Hadfield, John A., Parker, Anthony W., Towrie, Mike
Published in Biomedical spectroscopy and imaging (2014)
Published in Biomedical spectroscopy and imaging (2014)
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