Antibody-drug conjugates: an emerging modality for the treatment of cancer
Leal, Mauricio, Sapra, Puja, Hurvitz, Sara A., Senter, Peter, Wahl, Alan, Schutten, Melissa, Shah, Dhaval K., Haddish-Berhane, Nahor, Kabbarah, Omar
Published in Annals of the New York Academy of Sciences (01.08.2014)
Published in Annals of the New York Academy of Sciences (01.08.2014)
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Journal Article
Effect of Erdafitinib on the Pharmacokinetics of Midazolam and Metformin in Patients With Advanced Solid Tumors Harboring FGFR Gene Alterations
Zhu, Wei, Baig, Mahadi, Naini, Vahid, De Meulder, Marc, Akapame, Sydney, De Zwart, Loeckie, Haddish‐Berhane, Nahor, Triantos, Spyros
Published in Clinical pharmacology in drug development (01.10.2024)
Published in Clinical pharmacology in drug development (01.10.2024)
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Journal Article
Bioequivalence of 240 mg Apalutamide Tablets and Preparation in Aqueous Food Vehicles for Alternative Administration
Yu, Alex, Van Uffel, Mieke, Jiao, Juhui J., Rosales, Rosamerlinda, Erba, Maura, Haddish‐Berhane, Nahor
Published in Clinical pharmacology in drug development (01.04.2024)
Published in Clinical pharmacology in drug development (01.04.2024)
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Journal Article
Teclistamab: Mechanism of action, clinical, and translational science
Guo, Yue, Quijano Cardé, Natalia A., Kang, Lijuan, Verona, Raluca, Banerjee, Arnob, Kobos, Rachel, Chastain, Katherine, Uhlar, Clarissa, Pillarisetti, Kodandaram, Doyle, Margaret, Smit, Jennifer, Haddish‐Berhane, Nahor, Ouellet, Daniele
Published in Clinical and translational science (01.01.2024)
Published in Clinical and translational science (01.01.2024)
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Journal Article
Determination and Confirmation of Recommended Ph2 Dose of Amivantamab in Epidermal Growth Factor Receptor Exon 20 Insertion Non‐Small Cell Lung Cancer
Haddish‐Berhane, Nahor, Su, Yaming, Russu, Alberto, Thayu, Meena, Knoblauch, Roland E., Mehta, Jaydeep, Xie, John, Gibbs, Eric, Sun, Yu‐Nien, Zhou, Honghui
Published in Clinical pharmacology and therapeutics (01.03.2024)
Published in Clinical pharmacology and therapeutics (01.03.2024)
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Journal Article
Dose Optimization in Oncology Drug Development: An International Consortium for Innovation and Quality in Pharmaceutical Development White Paper
Samineni, Divya, Venkatakrishnan, Karthik, Othman, Ahmed A., Pithavala, Yazdi K., Poondru, Srinivasu, Patel, Chirag, Vaddady, Pavan, Ankrom, Wendy, Ramanujan, Saroja, Budha, Nageshwar, Wu, Michael, Haddish‐Berhane, Nahor, Fritsch, Holger, Hussain, Azher, Kanodia, Jitendra, Li, Meng, Li, Mengyao, Melhem, Murad, Parikh, Apurvasena, Upreti, Vijay V., Gupta, Neeraj
Published in Clinical pharmacology and therapeutics (01.09.2024)
Published in Clinical pharmacology and therapeutics (01.09.2024)
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Journal Article
Preclinical to Clinical Translation of Antibody-Drug Conjugates Using PK/PD Modeling: a Retrospective Analysis of Inotuzumab Ozogamicin
Betts, Alison M., Haddish-Berhane, Nahor, Tolsma, John, Jasper, Paul, King, Lindsay E., Sun, Yongliang, Chakrapani, Subramanyam, Shor, Boris, Boni, Joseph, Johnson, Theodore R.
Published in The AAPS journal (01.09.2016)
Published in The AAPS journal (01.09.2016)
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Journal Article
Discovery of (S)-6-(3-Cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic Acid as a Hepatoselective Glucokinase Activator Clinical Candidate for Treating Type 2 Diabetes Mellitus
Pfefferkorn, Jeffrey A, Guzman-Perez, Angel, Litchfield, John, Aiello, Robert, Treadway, Judith L, Pettersen, John, Minich, Martha L, Filipski, Kevin J, Jones, Christopher S, Tu, Meihua, Aspnes, Gary, Risley, Hud, Bian, Jianwei, Stevens, Benjamin D, Bourassa, Patricia, D’Aquila, Theresa, Baker, Levenia, Barucci, Nicole, Robertson, Alan S, Bourbonais, Francis, Derksen, David R, MacDougall, Margit, Cabrera, Over, Chen, Jing, Lapworth, Amanda Lee, Landro, James A, Zavadoski, William J, Atkinson, Karen, Haddish-Berhane, Nahor, Tan, Beijing, Yao, Lili, Kosa, Rachel E, Varma, Manthena V, Feng, Bo, Duignan, David B, El-Kattan, Ayman, Murdande, Sharad, Liu, Shenping, Ammirati, Mark, Knafels, John, DaSilva-Jardine, Paul, Sweet, Laurel, Liras, Spiros, Rolph, Timothy P
Published in Journal of medicinal chemistry (09.02.2012)
Published in Journal of medicinal chemistry (09.02.2012)
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Journal Article
On translation of antibody drug conjugates efficacy from mouse experimental tumors to the clinic: a PK/PD approach
Haddish-Berhane, Nahor, Shah, Dhaval K., Ma, Dangshe, Leal, Mauricio, Gerber, Hans-Peter, Sapra, Puja, Barton, Hugh A., Betts, Alison M.
Published in Journal of pharmacokinetics and pharmacodynamics (01.10.2013)
Published in Journal of pharmacokinetics and pharmacodynamics (01.10.2013)
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Journal Article
Cardiac Safety Assessment of Lazertinib: Findings From Patients With EGFR Mutation-Positive Advanced NSCLC and Preclinical Studies
Jang, Seong Bok, Kim, Kyeong Bae, Sim, Sujin, Cho, Byoung Chul, Ahn, Myung-Ju, Han, Ji-Youn, Kim, Sang-We, Lee, Ki Hyeong, Cho, Eun Kyung, Haddish-Berhane, Nahor, Mehta, Jaydeep, Oh, Se-Woong
Published in JTO clinical and research reports (01.10.2021)
Published in JTO clinical and research reports (01.10.2021)
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Journal Article
Pharmacodynamic Model of Sodium–Glucose Transporter 2 (SGLT2) Inhibition: Implications for Quantitative Translational Pharmacology
Maurer, Tristan S., Ghosh, Avijit, Haddish-Berhane, Nahor, Sawant-Basak, Aarti, Boustany-Kari, Carine M., She, Li, Leininger, Michael T., Zhu, Tong, Tugnait, Meera, Yang, Xin, Kimoto, Emi, Mascitti, Vincent, Robinson, Ralph P.
Published in The AAPS journal (01.12.2011)
Published in The AAPS journal (01.12.2011)
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Journal Article
SIMDOT-AbMe: Microphysiologically Based Simulation Tool for Quantitative Prediction of Systemic and Local Bioavailability of Targeted Oral Delivery Formulations
HADDISH-BERHANE, Nahor, FARHADI, Ashkan, NYQUIST, Chell, HAGHIGHI, Kamyar, KESHAVARZIAN, Ali
Published in Drug metabolism and disposition (01.03.2009)
Published in Drug metabolism and disposition (01.03.2009)
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Journal Article
Biological variability and targeted delivery of therapeutics for inflammatory bowel diseases: an in silico approach
Haddish-Berhane, Nahor, Farhadi, Ashkan, Nyquist, Chell, Haghighi, Kamyar, Keshavarzian, Ali
Published in Inflammation & allergy drug targets (01.03.2007)
Published in Inflammation & allergy drug targets (01.03.2007)
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Journal Article
PRMT5 억제제를 사용하여 암을 치료하는 방법
GUO YUE, QUINN HILLARY JOY MILLAR, WU TONGFEI, PACKMAN KATHRYN ELIZABETH, MANNENS GEERT S.J, LAURING JOSH, XIE HONG, HADDISH BERHANE NAHOR, GREWAY ANTHONY T, ZHOU JUNGUO, BREHMER DIRK
Year of Publication 14.02.2022
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Year of Publication 14.02.2022
Patent
Amivantamab in EGFR Exon 20 Insertion-Mutated Non-Small-Cell Lung Cancer Progressing on Platinum Chemotherapy: Initial Results From the CHRYSALIS Phase I Study
Park, Keunchil, Haura, Eric B, Leighl, Natasha B, Mitchell, Paul, Shu, Catherine A, Girard, Nicolas, Viteri, Santiago, Han, Ji-Youn, Kim, Sang-We, Lee, Chee Khoon, Sabari, Joshua K, Spira, Alexander I, Yang, Tsung-Ying, Kim, Dong-Wan, Lee, Ki Hyeong, Sanborn, Rachel E, Trigo, José, Goto, Koichi, Lee, Jong-Seok, Yang, James Chih-Hsin, Govindan, Ramaswamy, Bauml, Joshua M, Garrido, Pilar, Krebs, Matthew G, Reckamp, Karen L, Xie, John, Curtin, Joshua C, Haddish-Berhane, Nahor, Roshak, Amy, Millington, Dawn, Lorenzini, Patricia, Thayu, Meena, Knoblauch, Roland E, Cho, Byoung Chul
Published in Journal of clinical oncology (20.10.2021)
Published in Journal of clinical oncology (20.10.2021)
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Journal Article
Model-Based Exploration of the Impact of Prophylactic Tocilizumab on IL-6 Dynamics in Multiple Myeloma Patients Receiving Teclistamab Treatment
Zhou, Jia, Vishwamitra, Deeksha, Guo, Yue, Verona, Raluca, Perales Puchalt, Alfredo, Stephenson, Tara, Hodin, Caroline, Banerjee, Arnob, Chastain, Katherine, Haddish-Berhane, Nahor, Wang, Weirong
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Demonstrating Bioequivalence for Two Dose Strengths of Niraparib and Abiraterone Acetate Dual-Action Tablets Versus Single Agents: Utility of Clinical Study Data Supplemented with Modeling and Simulation
Yu, Alex, Hazra, Anasuya, Jiao, James Juhui, Hellemans, Peter, Mitselos, Anna, Tian, Hui, Ruixo, Juan Jose Perez, Haddish-Berhane, Nahor, Ouellet, Daniele, Russu, Alberto
Published in Clinical pharmacokinetics (01.04.2024)
Published in Clinical pharmacokinetics (01.04.2024)
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Journal Article
A Translational Quantitative Systems Pharmacology Model for CD3 Bispecific Molecules: Application to Quantify T Cell-Mediated Tumor Cell Killing by P-Cadherin LP DART
Betts, Alison, Haddish-Berhane, Nahor, Shah, Dhaval K., van der Graaf, Piet H., Barletta, Frank, King, Lindsay, Clark, Tracey, Kamperschroer, Cris, Root, Adam, Hooper, Andrea, Chen, Xiaoying
Published in The AAPS journal (22.05.2019)
Published in The AAPS journal (22.05.2019)
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