A cell-free nanobody engineering platform rapidly generates SARS-CoV-2 neutralizing nanobodies
Chen, Xun, Gentili, Matteo, Hacohen, Nir, Regev, Aviv
Published in Nature communications (17.09.2021)
Published in Nature communications (17.09.2021)
Get full text
Journal Article
Systematic comparison of single-cell and single-nucleus RNA-sequencing methods
Ding, Jiarui, Adiconis, Xian, Simmons, Sean K., Kowalczyk, Monika S., Hession, Cynthia C., Marjanovic, Nemanja D., Hughes, Travis K., Wadsworth, Marc H., Burks, Tyler, Nguyen, Lan T., Kwon, John Y. H., Barak, Boaz, Ge, William, Kedaigle, Amanda J., Carroll, Shaina, Li, Shuqiang, Hacohen, Nir, Rozenblatt-Rosen, Orit, Shalek, Alex K., Villani, Alexandra-Chloé, Regev, Aviv, Levin, Joshua Z.
Published in Nature biotechnology (01.06.2020)
Published in Nature biotechnology (01.06.2020)
Get full text
Journal Article
An immune-cell signature of bacterial sepsis
Reyes, Miguel, Filbin, Michael R., Bhattacharyya, Roby P., Billman, Kianna, Eisenhaure, Thomas, Hung, Deborah T., Levy, Bruce D., Baron, Rebecca M., Blainey, Paul C., Goldberg, Marcia B., Hacohen, Nir
Published in Nature medicine (01.03.2020)
Published in Nature medicine (01.03.2020)
Get full text
Journal Article
Full-length transcriptome assembly from RNA-Seq data without a reference genome
Friedman, Nir, Regev, Aviv, Grabherr, Manfred G, Haas, Brian J, Yassour, Moran, Levin, Joshua Z, Thompson, Dawn A, Amit, Ido, Adiconis, Xian, Fan, Lin, Raychowdhury, Raktima, Zeng, Qiandong, Chen, Zehua, Mauceli, Evan, Hacohen, Nir, Gnirke, Andreas, Rhind, Nicholas, di Palma, Federica, Birren, Bruce W, Nusbaum, Chad, Lindblad-Toh, Kerstin
Published in Nature biotechnology (01.07.2011)
Published in Nature biotechnology (01.07.2011)
Get full text
Journal Article
Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection
Li, Bo, Clohisey, Sara M., Chia, Bing Shao, Wang, Bo, Cui, Ang, Eisenhaure, Thomas, Schweitzer, Lawrence D., Hoover, Paul, Parkinson, Nicholas J., Nachshon, Aharon, Smith, Nikki, Regan, Tim, Farr, David, Gutmann, Michael U., Bukhari, Syed Irfan, Law, Andrew, Sangesland, Maya, Gat-Viks, Irit, Digard, Paul, Vasudevan, Shobha, Lingwood, Daniel, Dockrell, David H., Doench, John G., Baillie, J. Kenneth, Hacohen, Nir
Published in Nature communications (09.01.2020)
Published in Nature communications (09.01.2020)
Get full text
Journal Article
Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors
Villani, Alexandra-Chloé, Satija, Rahul, Reynolds, Gary, Sarkizova, Siranush, Shekhar, Karthik, Fletcher, James, Griesbeck, Morgane, Butler, Andrew, Zheng, Shiwei, Lazo, Suzan, Jardine, Laura, Dixon, David, Stephenson, Emily, Nilsson, Emil, Grundberg, Ida, McDonald, David, Filby, Andrew, Li, Weibo, De Jager, Philip L., Rozenblatt-Rosen, Orit, Lane, Andrew A., Haniffa, Muzlifah, Regev, Aviv, Hacohen, Nir
Published in Science (American Association for the Advancement of Science) (21.04.2017)
Published in Science (American Association for the Advancement of Science) (21.04.2017)
Get full text
Journal Article
Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses
Amit, Ido, Garber, Manuel, Chevrier, Nicolas, Leite, Ana Paula, Donner, Yoni, Eisenhaure, Thomas, Guttman, Mitchell, Grenier, Jennifer K, Li, Weibo, Zuk, Or, Schubert, Lisa A, Birditt, Brian, Shay, Tal, Goren, Alon, Zhang, Xiaolan, Smith, Zachary, Deering, Raquel, McDonald, Rebecca C, Cabili, Moran, Bernstein, Bradley E, Rinn, John L, Meissner, Alex, Root, David E, Hacohen, Nir, Regev, Aviv
Published in Science (American Association for the Advancement of Science) (09.10.2009)
Published in Science (American Association for the Advancement of Science) (09.10.2009)
Get full text
Journal Article
A large peptidome dataset improves HLA class I epitope prediction across most of the human population
Sarkizova, Siranush, Klaeger, Susan, Le, Phuong M., Li, Letitia W., Oliveira, Giacomo, Keshishian, Hasmik, Hartigan, Christina R., Zhang, Wandi, Braun, David A., Ligon, Keith L., Bachireddy, Pavan, Zervantonakis, Ioannis K., Rosenbluth, Jennifer M., Ouspenskaia, Tamara, Law, Travis, Justesen, Sune, Stevens, Jonathan, Lane, William J., Eisenhaure, Thomas, Lan Zhang, Guang, Clauser, Karl R., Hacohen, Nir, Carr, Steven A., Wu, Catherine J., Keskin, Derin B.
Published in Nature biotechnology (01.02.2020)
Published in Nature biotechnology (01.02.2020)
Get full text
Journal Article
Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma
Hu, Zhuting, Leet, Donna E., Allesøe, Rosa L., Oliveira, Giacomo, Li, Shuqiang, Luoma, Adrienne M., Liu, Jinyan, Forman, Juliet, Huang, Teddy, Iorgulescu, J. Bryan, Holden, Rebecca, Sarkizova, Siranush, Gohil, Satyen H., Redd, Robert A., Sun, Jing, Elagina, Liudmila, Giobbie-Hurder, Anita, Zhang, Wandi, Peter, Lauren, Ciantra, Zoe, Rodig, Scott, Olive, Oriol, Shetty, Keerthi, Pyrdol, Jason, Uduman, Mohamed, Lee, Patrick C., Bachireddy, Pavan, Buchbinder, Elizabeth I., Yoon, Charles H., Neuberg, Donna, Pentelute, Bradley L., Hacohen, Nir, Livak, Kenneth J., Shukla, Sachet A., Olsen, Lars Rønn, Barouch, Dan H., Wucherpfennig, Kai W., Fritsch, Edward F., Keskin, Derin B., Wu, Catherine J., Ott, Patrick A.
Published in Nature medicine (01.03.2021)
Published in Nature medicine (01.03.2021)
Get full text
Journal Article
Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer
Ouspenskaia, Tamara, Law, Travis, Clauser, Karl R., Klaeger, Susan, Sarkizova, Siranush, Aguet, François, Li, Bo, Christian, Elena, Knisbacher, Binyamin A., Le, Phuong M., Hartigan, Christina R., Keshishian, Hasmik, Apffel, Annie, Oliveira, Giacomo, Zhang, Wandi, Chen, Sarah, Chow, Yuen Ting, Ji, Zhe, Jungreis, Irwin, Shukla, Sachet A., Justesen, Sune, Bachireddy, Pavan, Kellis, Manolis, Getz, Gad, Hacohen, Nir, Keskin, Derin B., Carr, Steven A., Wu, Catherine J., Regev, Aviv
Published in Nature biotechnology (01.02.2022)
Published in Nature biotechnology (01.02.2022)
Get full text
Journal Article
Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction
Abelin, Jennifer G., Keskin, Derin B., Sarkizova, Siranush, Hartigan, Christina R., Zhang, Wandi, Sidney, John, Stevens, Jonathan, Lane, William, Zhang, Guang Lan, Eisenhaure, Thomas M., Clauser, Karl R., Hacohen, Nir, Rooney, Michael S., Carr, Steven A., Wu, Catherine J.
Published in Immunity (Cambridge, Mass.) (21.02.2017)
Published in Immunity (Cambridge, Mass.) (21.02.2017)
Get full text
Journal Article
Cumulus provides cloud-based data analysis for large-scale single-cell and single-nucleus RNA-seq
Li, Bo, Gould, Joshua, Yang, Yiming, Sarkizova, Siranush, Tabaka, Marcin, Ashenberg, Orr, Rosen, Yanay, Slyper, Michal, Kowalczyk, Monika S., Villani, Alexandra-Chloé, Tickle, Timothy, Hacohen, Nir, Rozenblatt-Rosen, Orit, Regev, Aviv
Published in Nature methods (01.08.2020)
Published in Nature methods (01.08.2020)
Get full text
Journal Article
Lineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomics
Ludwig, Leif S., Lareau, Caleb A., Ulirsch, Jacob C., Christian, Elena, Muus, Christoph, Li, Lauren H., Pelka, Karin, Ge, Will, Oren, Yaara, Brack, Alison, Law, Travis, Rodman, Christopher, Chen, Jonathan H., Boland, Genevieve M., Hacohen, Nir, Rozenblatt-Rosen, Orit, Aryee, Martin J., Buenrostro, Jason D., Regev, Aviv, Sankaran, Vijay G.
Published in Cell (07.03.2019)
Published in Cell (07.03.2019)
Get full text
Journal Article
Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes
Shukla, Sachet A, Rooney, Michael S, Rajasagi, Mohini, Tiao, Grace, Dixon, Philip M, Lawrence, Michael S, Stevens, Jonathan, Lane, William J, Dellagatta, Jamie L, Steelman, Scott, Sougnez, Carrie, Cibulskis, Kristian, Kiezun, Adam, Hacohen, Nir, Brusic, Vladimir, Wu, Catherine J, Getz, Gad
Published in Nature biotechnology (01.11.2015)
Published in Nature biotechnology (01.11.2015)
Get full text
Journal Article
CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling
Platt, Randall J., Chen, Sidi, Zhou, Yang, Yim, Michael J., Swiech, Lukasz, Kempton, Hannah R., Dahlman, James E., Parnas, Oren, Eisenhaure, Thomas M., Jovanovic, Marko, Graham, Daniel B., Jhunjhunwala, Siddharth, Heidenreich, Matthias, Xavier, Ramnik J., Langer, Robert, Anderson, Daniel G., Hacohen, Nir, Regev, Aviv, Feng, Guoping, Sharp, Phillip A., Zhang, Feng
Published in Cell (09.10.2014)
Published in Cell (09.10.2014)
Get full text
Journal Article
Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells
Shalek, Alex K., Satija, Rahul, Adiconis, Xian, Gertner, Rona S., Gaublomme, Jellert T., Raychowdhury, Raktima, Schwartz, Schraga, Yosef, Nir, Malboeuf, Christine, Lu, Diana, Trombetta, John J., Gennert, Dave, Gnirke, Andreas, Goren, Alon, Hacohen, Nir, Levin, Joshua Z., Park, Hongkun, Regev, Aviv
Published in Nature (London) (13.06.2013)
Published in Nature (London) (13.06.2013)
Get full text
Journal Article
Dynamic profiling of the protein life cycle in response to pathogens
Jovanovic, Marko, Rooney, Michael S., Mertins, Philipp, Przybylski, Dariusz, Chevrier, Nicolas, Satija, Rahul, Rodriguez, Edwin H., Fields, Alexander P., Schwartz, Schraga, Raychowdhury, Raktima, Mumbach, Maxwell R., Eisenhaure, Thomas, Rabani, Michal, Gennert, Dave, Lu, Diana, Delorey, Toni, Weissman, Jonathan S., Carr, Steven A., Hacohen, Nir, Regev, Aviv
Published in Science (American Association for the Advancement of Science) (06.03.2015)
Published in Science (American Association for the Advancement of Science) (06.03.2015)
Get full text
Journal Article
Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis
Mizoguchi, Fumitaka, Slowikowski, Kamil, Wei, Kevin, Marshall, Jennifer L., Rao, Deepak A., Chang, Sook Kyung, Nguyen, Hung N., Noss, Erika H., Turner, Jason D., Earp, Brandon E., Blazar, Philip E., Wright, John, Simmons, Barry P., Donlin, Laura T., Kalliolias, George D., Goodman, Susan M., Bykerk, Vivian P., Ivashkiv, Lionel B., Lederer, James A., Hacohen, Nir, Nigrovic, Peter A., Filer, Andrew, Buckley, Christopher D., Raychaudhuri, Soumya, Brenner, Michael B.
Published in Nature communications (23.02.2018)
Published in Nature communications (23.02.2018)
Get full text
Journal Article
Dnase2a deficiency uncovers lysosomal clearance of damaged nuclear DNA via autophagy
Lan, Yuk Yuen, Londoño, Diana, Bouley, Richard, Rooney, Michael S, Hacohen, Nir
Published in Cell reports (Cambridge) (09.10.2014)
Published in Cell reports (Cambridge) (09.10.2014)
Get full text
Journal Article