Quantitative analysis of amino acid metabolism in liver cancer links glutamate excretion to nucleotide synthesis
Nilsson, Avlant, Haanstra, Jurgen R., Engqvist, Martin, Gerding, Albert, Bakker, Barbara M., Klingmüller, Ursula, Teusink, Bas, Nielsen, Jens
Published in Proceedings of the National Academy of Sciences - PNAS (12.05.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (12.05.2020)
Get full text
Journal Article
Transcriptome‐wide analysis of trypanosome mRNA decay reveals complex degradation kinetics and suggests a role for co‐transcriptional degradation in determining mRNA levels
Fadda, Abeer, Ryten, Mark, Droll, Dorothea, Rojas, Federico, Färber, Valentin, Haanstra, Jurgen R., Merce, Clemetine, Bakker, Barbara M., Matthews, Keith, Clayton, Christine
Published in Molecular microbiology (01.10.2014)
Published in Molecular microbiology (01.10.2014)
Get full text
Journal Article
Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia
Beekman, Renée, Valkhof, Marijke G., Sanders, Mathijs A., van Strien, Paulette M.H., Haanstra, Jurgen R., Broeders, Lianne, Geertsma-Kleinekoort, Wendy M., Veerman, Anjo J.P., Valk, Peter J.M., Verhaak, Roel G., Löwenberg, Bob, Touw, Ivo P.
Published in Blood (31.05.2012)
Published in Blood (31.05.2012)
Get full text
Journal Article
How much (ATP) does it cost to build a trypanosome? A theoretical study on the quantity of ATP needed to maintain and duplicate a bloodstream-form Trypanosoma brucei cell
Nascimento, Janaina F, Souza, Rodolpho O O, Alencar, Mayke B, Marsiccobetre, Sabrina, Murillo, Ana M, Damasceno, Flávia S, Girard, Richard B M M, Marchese, Letícia, Luévano-Martinez, Luis A, Achjian, Renan W, Haanstra, Jurgen R, Michels, Paul A M, Silber, Ariel M
Published in PLoS pathogens (01.07.2023)
Published in PLoS pathogens (01.07.2023)
Get full text
Journal Article
Targeting pathogen metabolism without collateral damage to the host
Haanstra, Jurgen R., Gerding, Albert, Dolga, Amalia M., Sorgdrager, Freek J. H., Buist-Homan, Manon, du Toit, François, Faber, Klaas Nico, Holzhütter, Hermann-Georg, Szöör, Balázs, Matthews, Keith R., Snoep, Jacky L., Westerhoff, Hans V., Bakker, Barbara M.
Published in Scientific reports (13.01.2017)
Published in Scientific reports (13.01.2017)
Get full text
Journal Article
EVI1 is critical for the pathogenesis of a subset of MLL-AF9–rearranged AMLs
Bindels, Eric M.J., Havermans, Marije, Lugthart, Sanne, Erpelinck, Claudia, Wocjtowicz, Elizabeth, Krivtsov, Andrei V., Rombouts, Elwin, Armstrong, Scott A., Taskesen, Erdogan, Haanstra, Jurgen R., Beverloo, H. Berna, Döhner, Hartmut, Hudson, Wendy A., Kersey, John H., Delwel, Ruud, Kumar, Ashish R.
Published in Blood (14.06.2012)
Published in Blood (14.06.2012)
Get full text
Journal Article
Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes
Haanstra, Jurgen R, van Tuijl, Arjen, Kessler, Peter, Reijnders, Willem, Michels, Paul A.M, Westerhoff, Hans V, Parsons, Marilyn, Bakker, Barbara M
Published in Proceedings of the National Academy of Sciences - PNAS (18.11.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (18.11.2008)
Get full text
Journal Article
Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism
Pieretti, Simone, Haanstra, Jurgen R, Mazet, Muriel, Perozzo, Remo, Bergamini, Christian, Prati, Federica, Fato, Romana, Lenaz, Giorgio, Capranico, Giovanni, Brun, Reto, Bakker, Barbara M, Michels, Paul A M, Scapozza, Leonardo, Bolognesi, Maria Laura, Cavalli, Andrea
Published in PLoS neglected tropical diseases (01.01.2013)
Published in PLoS neglected tropical diseases (01.01.2013)
Get full text
Journal Article
Experimental and in Silico Analyses of Glycolytic Flux Control in Bloodstream Form Trypanosoma brucei
Albert, Marie-Astrid, Haanstra, Jurgen R, Hannaert, Véronique, Van Roy, Joris, Opperdoes, Fred R, Bakker, Barbara M, Michels, Paul A M
Published in The Journal of biological chemistry (05.08.2005)
Published in The Journal of biological chemistry (05.08.2005)
Get full text
Journal Article
A domino effect in drug action: from metabolic assault towards parasite differentiation
Haanstra, Jurgen R., Kerkhoven, Eduard J., van Tuijl, Arjen, Blits, Marjolein, Wurst, Martin, van Nuland, Rick, Albert, Marie‐Astrid, Michels, Paul A. M., Bouwman, Jildau, Clayton, Christine, Westerhoff, Hans V., Bakker, Barbara M.
Published in Molecular microbiology (01.01.2011)
Published in Molecular microbiology (01.01.2011)
Get full text
Journal Article
Differential regulation of agouti-related protein and neuropeptide Y in hypothalamic neurons following a stressful event
Kas, Martien J H, Bruijnzeel, Adrie W, Haanstra, Jurgen R, Wiegant, Victor M, Adan, Roger A H
Published in Journal of molecular endocrinology (01.08.2005)
Published in Journal of molecular endocrinology (01.08.2005)
Get full text
Journal Article
The silicon trypanosome: a test case of iterative model extension in systems biology
Achcar, Fiona, Fadda, Abeer, Haanstra, Jurgen R, Kerkhoven, Eduard J, Kim, Dong-Hyun, Leroux, Alejandro E, Papamarkou, Theodore, Rojas, Federico, Bakker, Barbara M, Barrett, Michael P, Clayton, Christine, Girolami, Mark, Krauth-Siegel, R Luise, Matthews, Keith R, Breitling, Rainer
Published in Advances in Microbial Physiology (2014)
Published in Advances in Microbial Physiology (2014)
Get full text
Journal Article
Book Chapter
The fully automated Sysmex XN-31 hematology analyzer can detect bloodstream form Trypanosoma brucei
Khartabil, Tania, van Schaik, Ron HN, Haanstra, Jurgen R., Koelewijn, Rob, Russcher, Henk, van Hellemond, Jaap J.
Published in Diagnostic microbiology and infectious disease (01.04.2024)
Published in Diagnostic microbiology and infectious disease (01.04.2024)
Get full text
Journal Article
Metabolite Depletion Affects Flux Profiling of Cell Lines
Nilsson, A., Haanstra, J.R., Teusink, B., Nielsen, J.
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.06.2018)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.06.2018)
Get full text
Journal Article
The unusual kinetics of lactate dehydrogenase of Schistosoma mansoni and their role in the rapid metabolic switch after penetration of the mammalian host
Bexkens, Michiel L., Martin, Olivier M.F., van den Heuvel, Jos M., Schmitz, Marion G.J., Teusink, Bas, Bakker, Barbara M., van Hellemond, Jaap J., Haanstra, Jurgen R., Walkinshaw, Malcolm D., Tielens, Aloysius G.M.
Published in International journal for parasitology (01.06.2024)
Published in International journal for parasitology (01.06.2024)
Get full text
Journal Article
Correction: How much (ATP) does it cost to build a trypanosome? A theoretical study on the quantity of ATP needed to maintain and duplicate a bloodstream-form Trypanosoma brucei cell
Nascimento, Janaina F., O. Souza, Rodolpho O., Alencar, Mayke B., Marsiccobetre, Sabrina, Murillo, Ana M., Damasceno, Flávia S., M. Girard, Richard B. M., Marchese, Letícia, Luévano-Martinez, Luis A., Achjian, Renan W., Haanstra, Jurgen R., M. Michels, Paul A., Silber, Ariel M.
Published in PLoS pathogens (30.08.2023)
Published in PLoS pathogens (30.08.2023)
Get full text
Journal Article