Design of a Phase 3 trial of intracoronary administration of human adenovirus 5 encoding human adenylyl cyclase type 6 (RT-100) gene transfer in patients with heart failure with reduced left ventricular ejection fraction: The FLOURISH Clinical Trial
Penny, William F., Henry, Timothy D., Watkins, Matthew W., Patel, Amit N., Hammond, H. Kirk
Published in The American heart journal (01.07.2018)
Published in The American heart journal (01.07.2018)
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Journal Article
Impact of blood factors on endothelial cell metabolism and function in two diverse heart failure models
Song, Young, Leem, Joseph, Dhanani, Mehul, McKirnan, M Dan, Ichikawa, Yasuhiro, Braza, Julie, Harrington, Elizabeth O, Hammond, H Kirk, Roth, David M, Patel, Hemal H
Published in PloS one (13.02.2023)
Published in PloS one (13.02.2023)
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Journal Article
Adenylyl cyclase 6 plays a minor role in the mouse inner ear and retina
Mathur, Pranav Dinesh, Zou, Junhuang, Neiswanger, Grace, Zhu, Daniel, Wang, Yong, Almishaal, Ali A, Vashist, Deepti, Hammond, H Kirk, Park, Albert H, Yang, Jun
Published in Scientific reports (01.05.2023)
Published in Scientific reports (01.05.2023)
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Journal Article
Adenylate Cyclase 6 Determines cAMP Formation and Aquaporin-2 Phosphorylation and Trafficking in Inner Medulla
RIEG, Timo, TONG TANG, MURRAY, Fiona, SCHROTH, Jana, INSEL, Paul A, FENTON, Robert A, KIRK HAMMOND, H, VALLON, Volker
Published in Journal of the American Society of Nephrology (01.12.2010)
Published in Journal of the American Society of Nephrology (01.12.2010)
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Journal Article
Urocortin 2 Gene Transfer Reduces the Adverse Effects of a Western Diet on Cardiac Function in Mice
Kim, Young Chul, Giamouridis, Dimosthenis, Lai, N Chin, Guo, Tracy, Xia, Bing, Fu, Zhenxing, Gao, Mei Hua, Hammond, H Kirk
Published in Human gene therapy (01.06.2019)
Published in Human gene therapy (01.06.2019)
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Journal Article
Cardiac-Directed Expression of Adenylyl Cyclase Catalytic Domain ( C1C2 ) Attenuates Deleterious Effects of Pressure Overload
Tan, Zhen, Giamouridis, Dimosthenis, Lai, N Chin, Kim, Young Chul, Guo, Tracy, Xia, Bing, Gao, Mei Hua, Hammond, H Kirk
Published in Human gene therapy (01.06.2019)
Published in Human gene therapy (01.06.2019)
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Journal Article
Human Oxidation-Specific Antibodies Reduce Foam Cell Formation and Atherosclerosis Progression
Tsimikas, Sotirios, MD, Miyanohara, Atsushi, PhD, Hartvigsen, Karsten, PhD, Merki, Esther, PhD, Shaw, Peter X., PhD, Chou, Meng-Yun, PhD, Pattison, Jennifer, BA, Torzewski, Michael, MD, Sollors, Janina, Friedmann, Theodore, MD, Lai, N. Chin, PhD, Hammond, H. Kirk, MD, Getz, Godfrey S., MD, PhD, Reardon, Catherine A., PhD, Li, Andrew C., MD, Banka, Carole L., PhD, Witztum, Joseph L., MD
Published in Journal of the American College of Cardiology (11.10.2011)
Published in Journal of the American College of Cardiology (11.10.2011)
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Journal Article
Urocortin 2 Gene Transfer Improves Heart Function in Aged Mice
Giamouridis, Dimosthenis, Gao, Mei Hua, Lai, N. Chin, Guo, Tracy, Miyanohara, Atsushi, Blankesteijn, W. Matthijs, Biessen, Erik A.L., Hammond, H. Kirk
Published in Molecular therapy (08.01.2020)
Published in Molecular therapy (08.01.2020)
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Journal Article
Reduced Collagen Deposition in Infarcted Myocardium Facilitates Induced Pluripotent Stem Cell Engraftment and Angiomyogenesis for Improvement of Left Ventricular Function
Dai, Bo, MD, PhD, Huang, Wei, MD, PhD, Xu, Meifeng, MD, PhD, Millard, Ronald W., PhD, Gao, Mei Hua, PhD, Hammond, H. Kirk, PhD, Menick, Donald R., PhD, Ashraf, Muhammad, PhD, Wang, Yigang, MD, PhD
Published in Journal of the American College of Cardiology (08.11.2011)
Published in Journal of the American College of Cardiology (08.11.2011)
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Journal Article
Constitutive inhibitory G protein activity upon adenylyl cyclase-dependent cardiac contractility is limited to adenylyl cyclase type 6
Bull Melsom, Caroline, Cosson, Marie-Victoire, Ørstavik, Øivind, Lai, Ngai Chin, Hammond, H Kirk, Osnes, Jan-Bjørn, Skomedal, Tor, Nikolaev, Viacheslav, Levy, Finn Olav, Krobert, Kurt Allen
Published in PloS one (07.06.2019)
Published in PloS one (07.06.2019)
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Journal Article
Adenylyl Cyclase Type 6 Deletion Decreases Left Ventricular Function via Impaired Calcium Handling
TONG TANG, MEI HUA GAO, CHIN LAI, N, FIRTH, Amy L, TAKAHASHI, Toshiyuki, GUO, Tracy, YUAN, Jason X.-J, ROTH, David M, KIRK HAMMOND, H
Published in Circulation (New York, N.Y.) (2008)
Published in Circulation (New York, N.Y.) (2008)
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Journal Article
Modulation of caveolins, integrins and plasma membrane repair proteins in anthracycline-induced heart failure in rabbits
Ichikawa, Yasuhiro, Zemljic-Harpf, Alice E, Zhang, Zheng, McKirnan, M Dan, Manso, Ana Maria, Ross, Robert S, Hammond, H Kirk, Patel, Hemal H, Roth, David M
Published in PloS one (12.05.2017)
Published in PloS one (12.05.2017)
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Journal Article
Activation of Cardiac Adenylyl Cyclase Expression Increases Function of the Failing Ischemic Heart in Mice
Lai, N. Chin, PhD, Tang, Tong, PhD, Gao, Mei Hua, PhD, Saito, Miho, MD, Takahashi, Toshiyuki, MD, PhD, Roth, David M., MD, PhD, Hammond, H. Kirk, MD
Published in Journal of the American College of Cardiology (15.04.2008)
Published in Journal of the American College of Cardiology (15.04.2008)
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Journal Article
Comparison of adeno-associated virus serotypes and delivery methods for cardiac gene transfer
Fang, Hongfei, Lai, Ngai Chin, Gao, Mei Hua, Miyanohara, Atsushi, Roth, David M, Tang, Tong, Hammond, H Kirk
Published in Human gene therapy. Part B. Methods (01.08.2012)
Published in Human gene therapy. Part B. Methods (01.08.2012)
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Journal Article
Urocortin 2 Gene Transfer Improves Glycemic Control and Reduces Retinopathy and Mortality in Murine Insulin Deficiency
Gao, Mei Hua, Giamouridis, Dimosthenis, Lai, N. Chin, Guo, Tracy, Xia, Bing, Kim, Young Chul, Huu, Viet Anh Nguyen, Skowronska-Krawczyk, Dorota, Lantier, Louise, Bhargava, Raag, Hammond, H. Kirk
Published in Molecular therapy. Methods & clinical development (12.06.2020)
Published in Molecular therapy. Methods & clinical development (12.06.2020)
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Journal Article
Stimulation of Renin Secretion by Catecholamines Is Dependent on Adenylyl Cyclases 5 and 6
Aldehni, Fadi, Tang, Tong, Madsen, Kirsten, Plattner, Michael, Schreiber, Andrea, Friis, Ulla G, Hammond, H. Kirk, Han, Pyung Lim, Schweda, Frank
Published in Hypertension (Dallas, Tex. 1979) (01.03.2011)
Published in Hypertension (Dallas, Tex. 1979) (01.03.2011)
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