Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies
Herold, Nikolas, Rudd, Sean G, Ljungblad, Linda, Sanjiv, Kumar, Myrberg, Ida Hed, Paulin, Cynthia B J, Heshmati, Yaser, Hagenkort, Anna, Kutzner, Juliane, Page, Brent D G, Calderón-Montaño, José M, Loseva, Olga, Jemth, Ann-Sofie, Bulli, Lorenzo, Axelsson, Hanna, Tesi, Bianca, Valerie, Nicholas C K, Höglund, Andreas, Bladh, Julia, Wiita, Elisée, Sundin, Mikael, Uhlin, Michael, Rassidakis, Georgios, Heyman, Mats, Tamm, Katja Pokrovskaja, Warpman-Berglund, Ulrika, Walfridsson, Julian, Lehmann, Sören, Grandér, Dan, Lundbäck, Thomas, Kogner, Per, Henter, Jan-Inge, Helleday, Thomas, Schaller, Torsten
Published in Nature medicine (01.02.2017)
Published in Nature medicine (01.02.2017)
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Journal Article
MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia
Sanjiv, Kumar, Calderón-Montaño, José Manuel, Pham, Therese M, Erkers, Tom, Tsuber, Viktoriia, Almlöf, Ingrid, Höglund, Andreas, Heshmati, Yaser, Seashore-Ludlow, Brinton, Nagesh Danda, Akhilesh, Gad, Helge, Wiita, Elisee, Göktürk, Camilla, Rasti, Azita, Friedrich, Stefanie, Centio, Anders, Estruch, Montserrat, Våtsveen, Thea Kristin, Struyf, Nona, Visnes, Torkild, Scobie, Martin, Koolmeister, Tobias, Henriksson, Martin, Wallner, Olov, Sandvall, Teresa, Lehmann, Sören, Theilgaard-Mönch, Kim, Garnett, Mathew J, Östling, Päivi, Walfridsson, Julian, Helleday, Thomas, Warpman Berglund, Ulrika
Published in Cancer research (Chicago, Ill.) (15.11.2021)
Published in Cancer research (Chicago, Ill.) (15.11.2021)
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Journal Article
Therapeutic Implications for the Induced Levels of Chk1 in Myc-Expressing Cancer Cells
HÖGLUND, Andreas, NILSSON, Lisa M, VEPPIL MURALIDHARAN, Somsundar, HASVOLD, Lisa A, MERTA, Philip, RUDELIUS, Martina, NIKOLOVA, Viktoriya, KELLER, Ulrich, NILSSON, Jonas A
Published in Clinical cancer research (15.11.2011)
Published in Clinical cancer research (15.11.2011)
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Journal Article
Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1
Llona-Minguez, Sabin, Höglund, Andreas, Jacques, Sylvain A, Johansson, Lars, Calderón-Montaño, José Manuel, Claesson, Magnus, Loseva, Olga, Valerie, Nicholas C. K, Lundbäck, Thomas, Piedrafita, Javier, Maga, Giovanni, Crespan, Emmanuele, Meijer, Laurent, Burgos Morón, Estefanía, Baranczewski, Pawel, Hagbjörk, Ann-Louise, Svensson, Richard, Wiita, Elisee, Almlöf, Ingrid, Visnes, Torkild, Jeppsson, Fredrik, Sigmundsson, Kristmundur, Jensen, Annika Jenmalm, Artursson, Per, Jemth, Ann-Sofie, Stenmark, Pål, Warpman Berglund, Ulrika, Scobie, Martin, Helleday, Thomas
Published in Journal of medicinal chemistry (11.02.2016)
Published in Journal of medicinal chemistry (11.02.2016)
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Journal Article
The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2'-deoxycytidine lesions
Orta, Manuel Luis, Höglund, Andreas, Calderón-Montaño, José Manuel, Domínguez, Inmaculada, Burgos-Morón, Estefanía, Visnes, Torkild, Pastor, Nuria, Ström, Cecilia, López-lázaro, Miguel, Helleday, Thomas
Published in Nucleic acids research (18.08.2014)
Published in Nucleic acids research (18.08.2014)
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Journal Article
Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors
Llona-Minguez, Sabin, Höglund, Andreas, Ghassemian, Artin, Desroses, Matthieu, Calderón-Montaño, José Manuel, Burgos Morón, Estefanía, Valerie, Nicholas C. K, Wiita, Elisee, Almlöf, Ingrid, Koolmeister, Tobias, Mateus, André, Cazares-Körner, Cindy, Sanjiv, Kumar, Homan, Evert, Loseva, Olga, Baranczewski, Pawel, Darabi, Masoud, Mehdizadeh, Amir, Fayezi, Shabnam, Jemth, Ann-Sofie, Warpman Berglund, Ulrika, Sigmundsson, Kristmundur, Lundbäck, Thomas, Jenmalm Jensen, Annika, Artursson, Per, Scobie, Martin, Helleday, Thomas
Published in Journal of medicinal chemistry (25.05.2017)
Published in Journal of medicinal chemistry (25.05.2017)
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Journal Article
Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1
Llona-Minguez, Sabin, Höglund, Andreas, Wiita, Elisee, Almlöf, Ingrid, Mateus, André, Calderón-Montaño, José Manuel, Cazares-Körner, Cindy, Homan, Evert, Loseva, Olga, Baranczewski, Pawel, Jemth, Ann-Sofie, Häggblad, Maria, Martens, Ulf, Lundgren, Bo, Artursson, Per, Lundbäck, Thomas, Jenmalm Jensen, Annika, Warpman Berglund, Ulrika, Scobie, Martin, Helleday, Thomas
Published in Journal of medicinal chemistry (09.03.2017)
Published in Journal of medicinal chemistry (09.03.2017)
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Journal Article
Chk2 deficiency in Myc overexpressing lymphoma cells elicits a synergistic lethal response in combination with PARP inhibition
Höglund, Andreas, Strömvall, Kerstin, Li, Yongmei, Forshell, Linus Plym, Nilsson, Jonas A.
Published in Cell cycle (Georgetown, Tex.) (15.10.2011)
Published in Cell cycle (Georgetown, Tex.) (15.10.2011)
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Journal Article
Glioblastoma and glioblastoma stem cells are dependent on functional MTH1
Pudelko, Linda, Rouhi, Pegah, Sanjiv, Kumar, Gad, Helge, Kalderén, Christina, Höglund, Andreas, Squatrito, Massimo, Schuhmacher, Alberto J, Edwards, Steven, Hägerstrand, Daniel, Berglund, Ulrika Warpman, Helleday, Thomas, Bräutigam, Lars
Published in Oncotarget (17.10.2017)
Published in Oncotarget (17.10.2017)
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Journal Article
5G Reduced Capability Devices: Analysis of Blocking Probability for Control Channels
Moloudi, Saeedeh, Mozaffari, Mohammad, Kittichokechai, Kittipong, Hoglund, Andreas, Kadan Veedu, Sandeep Narayanan, Eric Wang, Y.-P., Bergman, Johan
Published in 2023 IEEE Wireless Communications and Networking Conference (WCNC) (01.03.2023)
Published in 2023 IEEE Wireless Communications and Networking Conference (WCNC) (01.03.2023)
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Conference Proceeding
Correction to Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors
Llona-Minguez, Sabin, Höglund, Andreas, Ghassemian, Artin, Desroses, Matthieu, Calderón-Montaño, José Manuel, Burgos Morón, Estefanía, Valerie, Nicholas C. K, Wiita, Elisee, Almlöf, Ingrid, Koolmeister, Tobias, Mateus, André, Cazares-Körner, Cindy, Sanjiv, Kumar, Homan, Evert, Loseva, Olga, Baranczewski, Pawel, Darabi, Masoud, Mehdizadeh, Amir, Fayezi, Shabnam, Jemth, Ann-Sofie, Warpman Berglund, Ulrika, Sigmundsson, Kristmundur, Lundbäck, Thomas, Jenmalm Jensen, Annika, Artursson, Per, Scobie, Martin, Helleday, Thomas
Published in Journal of medicinal chemistry (14.09.2017)
Published in Journal of medicinal chemistry (14.09.2017)
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Journal Article
Inhibition of cellular FLICE-like inhibitory protein abolishes insensitivity to interferon-α and death receptor stimulation in resistant variants of the human U937 cell line
Blomberg, Jeanette, Höglund, Andreas, Eriksson, David, Ruuth, Kristina, Jacobsson, Maria, Lundgren, Erik, Nilsson, Jonas A.
Published in Apoptosis (London) (01.08.2011)
Published in Apoptosis (London) (01.08.2011)
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Journal Article