Valve-Related Hemodynamics Mediate Human Bicuspid Aortopathy: Insights From Wall Shear Stress Mapping
Guzzardi, David G, Barker, Alex J, van Ooij, Pim, Malaisrie, S Chris, Puthumana, Jyothy J, Belke, Darrell D, Mewhort, Holly E M, Svystonyuk, Daniyil A, Kang, Sean, Verma, Subodh, Collins, Jeremy, Carr, James, Bonow, Robert O, Markl, Michael, Thomas, James D, McCarthy, Patrick M, Fedak, Paul W M
Published in Journal of the American College of Cardiology (25.08.2015)
Published in Journal of the American College of Cardiology (25.08.2015)
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Journal Article
Commentary: Fluoroquinolone antibiotics are antiaortic
Guzzardi, David G., Dundas, Jameson, Fedak, Paul W.M.
Published in The Journal of thoracic and cardiovascular surgery (01.03.2022)
Published in The Journal of thoracic and cardiovascular surgery (01.03.2022)
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Journal Article
Induction of human aortic myofibroblast-mediated extracellular matrix dysregulation: A potential mechanism of fluoroquinolone-associated aortopathy
Guzzardi, David G., Teng, Guoqi, Kang, Sean, Geeraert, Patrick J., Pattar, Simranjit S., Svystonyuk, Daniyil A., Belke, Darrell D., Fedak, Paul W.M.
Published in The Journal of thoracic and cardiovascular surgery (01.01.2019)
Published in The Journal of thoracic and cardiovascular surgery (01.01.2019)
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Journal Article
Direct Effects of Empagliflozin on Extracellular Matrix Remodelling in Human Cardiac Myofibroblasts: Novel Translational Clues to Explain EMPA-REG OUTCOME Results
Kang, Sean, Verma, Subodh, Hassanabad, Ali Fatehi, Teng, Guoqi, Belke, Darrell D., Dundas, Jameson A., Guzzardi, David G., Svystonyuk, Daniyil A., Pattar, Simranjit S., Park, Daniel S.J., Turnbull, Jeannine D., Duff, Henry J., Tibbles, Lee Anne, Cunnington, Ryan H., Dyck, Jason R.B., Fedak, Paul W.M.
Published in Canadian journal of cardiology (01.04.2020)
Published in Canadian journal of cardiology (01.04.2020)
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Journal Article
The science of BAV aortopathy
Lo Presti, Federica, Guzzardi, David G., Bancone, Ciro, Fedak, Paul W.M., Della Corte, Alessandro
Published in Progress in cardiovascular diseases (01.07.2020)
Published in Progress in cardiovascular diseases (01.07.2020)
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Journal Article
Fluoroquinolone-Associated Type A Aortic Dissection in Alpha-1 Anti-Trypsin Deficiency
Guzzardi, David G., Hassanabad, Ali Fatehi, Bromley, Amy B., Fedak, Paul W.M.
Published in The Annals of thoracic surgery (01.12.2020)
Published in The Annals of thoracic surgery (01.12.2020)
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Journal Article
Epicardial Infarct Repair with Bioinductive Extracellular Matrix Promotes Vasculogenesis and Myocardial Recovery
Mewhort, Holly E.M., MD, Turnbull, Jeannine D., BSc, Satriano, Alessandro, PhD, Chow, Kelvin, PhD, Flewitt, Jacqueline A., MSc, Andrei, Adin-Cristian, PhD, Guzzardi, David G., BSc, Svystonyuk, Daniyil A., BSc, White, James A., MD, FRCSC, Fedak, Paul W.M., MD, PhD, FRCSC
Published in The Journal of heart and lung transplantation (01.05.2016)
Published in The Journal of heart and lung transplantation (01.05.2016)
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Journal Article
Monocytes increase human cardiac myofibroblast-mediated extracellular matrix remodeling through TGF-β1
Mewhort, Holly E M, Lipon, Brodie D, Svystonyuk, Daniyil A, Teng, Guoqi, Guzzardi, David G, Silva, Claudia, Yong, V Wee, Fedak, Paul W M
Published in American journal of physiology. Heart and circulatory physiology (15.03.2016)
Published in American journal of physiology. Heart and circulatory physiology (15.03.2016)
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Journal Article
Human pericardial proteoglycan 4 (lubricin): Implications for postcardiotomy intrathoracic adhesion formation
Park, Daniel S.J., Regmi, Suresh C., Svystonyuk, Daniyil A., Teng, Guoqi, Belke, Darrell, Turnbull, Jeannine, Guzzardi, David G., Kang, Sean, Cowman, Mary K., Schmidt, Tannin A., Fedak, Paul W.M.
Published in The Journal of thoracic and cardiovascular surgery (01.10.2018)
Published in The Journal of thoracic and cardiovascular surgery (01.10.2018)
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Journal Article
Aortic valve-mediated wall shear stress is heterogeneous and predicts regional aortic elastic fiber thinning in bicuspid aortic valve-associated aortopathy
Bollache, Emilie, Guzzardi, David G., Sattari, Samaneh, Olsen, Katherine E., Di Martino, Elena S., Malaisrie, S. Chris, van Ooij, Pim, Collins, Jeremy, Carr, James, McCarthy, Patrick M., Markl, Michael, Barker, Alex J., Fedak, Paul W.M.
Published in The Journal of thoracic and cardiovascular surgery (01.12.2018)
Published in The Journal of thoracic and cardiovascular surgery (01.12.2018)
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Journal Article
Real estate of the bicuspid aorta: location, location, location
Fedak, Paul W.M., MD PhD, Guzzardi, David G., BSc
Published in The Journal of thoracic and cardiovascular surgery (01.06.2016)
Published in The Journal of thoracic and cardiovascular surgery (01.06.2016)
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Journal Article
Effect of Active Cancer on the Cardiac Phenotype: A Cardiac Magnetic Resonance Imaging-Based Study of Myocardial Tissue Health and Deformation in Patients With Chemotherapy-Naïve Cancer
Labib, Dina, Satriano, Alessandro, Dykstra, Steven, Hansen, Reis, Mikami, Yoko, Guzzardi, David G, Slavikova, Zdenka, Feuchter, Patricia, Flewitt, Jacqueline, Rivest, Sandra, Sandonato, Rosa, Lydell, Carmen P, Howarth, Andrew G, Kolman, Louis, Clarke, Brian, Paterson, D Ian, Oudit, Gavin Y, Pituskin, Edith, Cheung, Winson Y, Lee, Joon, White, James A
Published in Journal of the American Heart Association (04.05.2021)
Published in Journal of the American Heart Association (04.05.2021)
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Journal Article
Acellular bioscaffolds redirect cardiac fibroblasts and promote functional tissue repair in rodents and humans with myocardial injury
Svystonyuk, Daniyil A, Mewhort, Holly E M, Hassanabad, Ali Fatehi, Heydari, Bobak, Mikami, Yoko, Turnbull, Jeannine D, Teng, Guoqi, Belke, Darrell D, Wagner, Karl T, Tarraf, Samar A, DiMartino, Elena S, White, James A, Flewitt, Jacqueline A, Cheung, Matthew, Guzzardi, David G, Kang, Sean, Fedak, Paul W M
Published in Scientific reports (11.06.2020)
Published in Scientific reports (11.06.2020)
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Journal Article
Fibroblast growth factor-2 regulates human cardiac myofibroblast-mediated extracellular matrix remodeling
Svystonyuk, Daniyil A, Ngu, Janet M C, Mewhort, Holly E M, Lipon, Brodie D, Teng, Guoqi, Guzzardi, David G, Malik, Getanshu, Belke, Darrell D, Fedak, Paul W M
Published in Journal of translational medicine (07.05.2015)
Published in Journal of translational medicine (07.05.2015)
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Journal Article
Bicuspid aortic valve aortopathy: mechanistic and clinical insights from recent studies
Guzzardi, David G, Verma, Subodh, Fedak, Paul W M
Published in Current opinion in cardiology (01.03.2017)
Published in Current opinion in cardiology (01.03.2017)
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Journal Article
Bioactive Extracellular Matrix Scaffold Promotes Adaptive Cardiac Remodeling and Repair
Mewhort, Holly E.M., MD, PhD, Svystonyuk, Daniyil A., BSc, Turnbull, Jeannine D., BSc, Teng, Guoqi, PhD, Belke, Darrell D., PhD, Guzzardi, David G., BSc, Park, Daniel S., BSc, Kang, Sean, BSc, Hollenberg, Morley D., MD, PhD, Fedak, Paul W.M., MD, PhD
Published in JACC. Basic to translational science (01.08.2017)
Published in JACC. Basic to translational science (01.08.2017)
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Journal Article
Normative healthy reference values for global and segmental 3D principal and geometry dependent strain from cine cardiac magnetic resonance imaging
Guzzardi, David G., White, James A., Labib, Dina, Dykstra, Steven, Flewitt, Jacqueline, Feuchter, Patricia, Sandonato, Rosa, Howarth, Andrew G., Lydell, Carmen P., Fine, Nowell M., Greiner, Russel, Satriano, Alessandro
Published in The international journal of cardiovascular imaging (01.01.2023)
Published in The international journal of cardiovascular imaging (01.01.2023)
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Journal Article
Elastin integrity in bicuspid valve-associated aortopathy is associated with altered biomechanical properties and influenced by age
Nightingale, Miriam, Guzzardi, David G., Barker, Alex J., Malaisrie, S. Chris, McCarthy, Patrick M., Markl, Michael, Martino, Elena S. Di, Fedak, Paul W. M.
Published in Annals of cardiothoracic surgery (01.07.2022)
Published in Annals of cardiothoracic surgery (01.07.2022)
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