Effect of FGF/FGFR pathway blocking on lung adenocarcinoma and its cancer‐associated fibroblasts
Hegab, Ahmed E, Ozaki, Mari, Kameyama, Naofumi, Gao, Jingtao, Kagawa, Shizuko, Yasuda, Hiroyuki, Soejima, Kenzo, Yin, Yongjun, Guzy, Robert D, Nakamura, Yoshikazu, Ornitz, David M, Betsuyaku, Tomoko
Published in The Journal of pathology (01.10.2019)
Published in The Journal of pathology (01.10.2019)
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Journal Article
Loss of the SdhB, but Not the SdhA, Subunit of Complex II Triggers Reactive Oxygen Species-Dependent Hypoxia-Inducible Factor Activation and Tumorigenesis
Guzy, Robert D., Sharma, Bhumika, Bell, Eric, Chandel, Navdeep S., Schumacker, Paul T.
Published in Molecular and Cellular Biology (01.01.2008)
Published in Molecular and Cellular Biology (01.01.2008)
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Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization
Lee, Tzu-Han, Yeh, Chih-Fan, Lee, Ying-Tung, Shih, Ying-Chun, Chen, Yen-Ting, Hung, Chen-Ting, You, Ming-Yi, Wu, Pei-Chen, Shentu, Tzu-Pin, Huang, Ru-Ting, Lin, Yu-Shan, Wu, Yueh-Feng, Lin, Sung-Jan, Lu, Frank-Leigh, Tsao, Po-Nien, Lin, Tzu-Hung, Lo, Shen-Chuan, Tseng, Yi-Shuan, Wu, Wan-Lin, Chen, Chiung-Nien, Wu, Chau-Chung, Lin, Shuei-Liong, Sperling, Anne I., Guzy, Robert D., Fang, Yun, Yang, Kai-Chien
Published in Nature communications (26.08.2020)
Published in Nature communications (26.08.2020)
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Journal Article
SARS-CoV-2 Infection Is Associated with Reduced Krüppel-like Factor 2 in Human Lung Autopsy
Wu, David, Lee, Tzu-Han, Huang, Ru-Ting, D Guzy, Robert, Schoettler, Nathan, Adegunsoye, Ayodeji, Mueller, Jeffrey, Husain, Aliya, I Sperling, Anne, Mutlu, Gökhan M, Fang, Yun
Published in American journal of respiratory cell and molecular biology (01.08.2021)
Published in American journal of respiratory cell and molecular biology (01.08.2021)
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Journal Article
Superoxide Generated at Mitochondrial Complex III Triggers Acute Responses to Hypoxia in the Pulmonary Circulation
WAYPA, Gregory B, MARKS, Jeremy D, GUZY, Robert D, MUNGAI, Paul T, SCHRIEWER, Jacqueline M, DOKIC, Danijela, BALL, Molly K, SCHUMACKER, Paul T
Published in American journal of respiratory and critical care medicine (15.02.2013)
Published in American journal of respiratory and critical care medicine (15.02.2013)
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Journal Article
Mitochondrial oxidant stress triggers cell death in simulated ischemia–reperfusion
Loor, Gabriel, Kondapalli, Jyothisri, Iwase, Hirotaro, Chandel, Navdeep S., Waypa, Gregory B., Guzy, Robert D., Vanden Hoek, Terry L., Schumacker, Paul T.
Published in Biochimica et biophysica acta (01.07.2011)
Published in Biochimica et biophysica acta (01.07.2011)
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Journal Article
Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing
Guzy, Robert D., Hoyos, Beatrice, Robin, Emmanuel, Chen, Hong, Liu, Liping, Mansfield, Kyle D., Simon, M. Celeste, Hammerling, Ulrich, Schumacker, Paul T.
Published in Cell metabolism (01.06.2005)
Published in Cell metabolism (01.06.2005)
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Oxidant Stress during Simulated Ischemia Primes Cardiomyocytes for Cell Death during Reperfusion
Robin, Emmanuel, Guzy, Robert D., Loor, Gabriel, Iwase, Hirotaro, Waypa, Gregory B., Marks, Jeremy D., Hoek, Terry L. Vanden, Schumacker, Paul T.
Published in The Journal of biological chemistry (29.06.2007)
Published in The Journal of biological chemistry (29.06.2007)
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Journal Article
Fibroblast Growth Factor 2 Augments Transforming Growth Factor Beta 1 Induced Epithelial-mesenchymal Transition in Lung Cell Culture Model
El-Baz, Lamis M F, Shoukry, Nahla M, Hafez, Hani S, Guzy, Robert D, Salem, Mohamed Labib
Published in Iranian journal of allergy, asthma, and immunology (25.08.2020)
Published in Iranian journal of allergy, asthma, and immunology (25.08.2020)
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Journal Article
Fibroblast growth factor 2 is required for epithelial recovery, but not for pulmonary fibrosis, in response to bleomycin
Guzy, Robert D, Stoilov, Ivan, Elton, Timothy J, Mecham, Robert P, Ornitz, David M
Published in American journal of respiratory cell and molecular biology (01.01.2015)
Published in American journal of respiratory cell and molecular biology (01.01.2015)
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Journal Article
Fibroblast growth factor 2 decreases bleomycin‐induced pulmonary fibrosis and inhibits fibroblast collagen production and myofibroblast differentiation
Koo, Hyun Young, El‐Baz, Lamis MF, House, StaceyL, Cilvik, Sarah N, Dorry, Samuel J, Shoukry, Nahla M, Salem, Mohamed L, Hafez, Hani S, Dulin, Nickolai O, Ornitz, David M, Guzy, Robert D
Published in The Journal of pathology (01.09.2018)
Published in The Journal of pathology (01.09.2018)
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Journal Article
Inhibition of Phosphoglycerate Dehydrogenase Attenuates Bleomycin-induced Pulmonary Fibrosis
Hamanaka, Robert B, Nigdelioglu, Recep, Meliton, Angelo Y, Tian, Yufeng, Witt, Leah J, O'Leary, Erin, Sun, Kaitlyn A, Woods, Parker S, Wu, David, Ansbro, Brandon, Ard, Shawn, Rohde, Jason M, Dulin, Nickolai O, Guzy, Robert D, Mutlu, Gökhan M
Published in American journal of respiratory cell and molecular biology (01.05.2018)
Published in American journal of respiratory cell and molecular biology (01.05.2018)
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Journal Article
Sustained Smad2 Phosphorylation Is Required for Myofibroblast Transformation in Response to TGF-β
Ard, Shawn, Reed, Eleanor B, Smolyaninova, Larisa V, Orlov, Sergei N, Mutlu, Gökhan M, Guzy, Robert D, Dulin, Nickolai O
Published in American journal of respiratory cell and molecular biology (01.03.2019)
Published in American journal of respiratory cell and molecular biology (01.03.2019)
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Journal Article
Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-α activation
Mansfield, Kyle D., Guzy, Robert D., Pan, Yi, Young, Regina M., Cash, Timothy P., Schumacker, Paul T., Simon, M. Celeste
Published in Cell metabolism (01.06.2005)
Published in Cell metabolism (01.06.2005)
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