Humanized xenobiotic response in mice expressing nuclear receptor SXR
Evans, Ronald M, Xie, Wen, Barwick, Joyce L, Downes, Michael, Blumberg, Bruce, Simon, Cynthia M, Nelson, Michael C, Neuschwander-Tetri, Brent A, Brunt, Elizabeth M, Guzelian, Philip S
Published in Nature (London) (27.07.2000)
Published in Nature (London) (27.07.2000)
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Evidence-based causation in toxicology: A 10-year retrospective
James, RC, Britt, JK, Halmes, NC, Guzelian, PS
Published in Human & experimental toxicology (01.12.2015)
Published in Human & experimental toxicology (01.12.2015)
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Comments on recent discussions providing differing causation methodologies
James, RC, Britt, J, Halmes, NC, Guzelian, PS
Published in Human & experimental toxicology (01.01.2014)
Published in Human & experimental toxicology (01.01.2014)
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Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450: studies in rats and patients
WATKINS, P. B, MURRAY, S. A, WINKELMAN, L. G, HEUMAN, D. M, WRIGHTON, S. A, GUZELIAN, P. S
Published in The Journal of clinical investigation (01.02.1989)
Published in The Journal of clinical investigation (01.02.1989)
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Clear path: towards an evidence-based toxicology (EBT)
Guzelian, PS, Victoroff, MS, Halmes, C, James, RC
Published in Human & experimental toxicology (01.02.2009)
Published in Human & experimental toxicology (01.02.2009)
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Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta
SCHUETZ, J. D, KAUMA, S, GUZELIAN, P. S
Published in The Journal of clinical investigation (01.08.1993)
Published in The Journal of clinical investigation (01.08.1993)
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Five of 12 Forms of Vaccinia Virus-Expressed Human Hepatic Cytochrome P450 Metabolically Activate Aflatoxin B1
Aoyama, Toshifumi, Yamano, Shigeru, Guzelian, Philip S., Gelboin, Harry V., Gonzalez, Frank J.
Published in Proceedings of the National Academy of Sciences - PNAS (01.06.1990)
Published in Proceedings of the National Academy of Sciences - PNAS (01.06.1990)
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Trans-species gene transfer for analysis of glucocorticoid-inducible transcriptional activation of transiently expressed human CYP3A4 and rabbit CYP3A6 in primary cultures of adult rat and rabbit hepatocytes
Barwick, J L, Quattrochi, L C, Mills, A S, Potenza, C, Tukey, R H, Guzelian, P S
Published in Molecular pharmacology (01.07.1996)
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Published in Molecular pharmacology (01.07.1996)
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Characterization of human liver cytochromes P-450 involved in theophylline metabolism
Sarkar, M A, Hunt, C, Guzelian, P S, Karnes, H T
Published in Drug metabolism and disposition (01.01.1992)
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Published in Drug metabolism and disposition (01.01.1992)
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Regulation of human liver cytochromes P-450 in family 3A in primary and continuous culture of human hepatocytes
Schuetz, E G, Schuetz, J D, Strom, S C, Thompson, M T, Fisher, R A, Molowa, D T, Li, D, Guzelian, P S
Published in Hepatology (Baltimore, Md.) (01.11.1993)
Published in Hepatology (Baltimore, Md.) (01.11.1993)
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Paradoxical Transcriptional Activation of Rat Liver Cytochrome P-450 3A1 by Dexamethasone and the Antiglucocorticoid Pregnenolone 16α- Carbonitrile: Analysis by Transient Transfection into Primary Monolayer Cultures of Adult Rat Hepatocytes
Burger, Hans-Joerg, Schuetz, John D., Schuetz, Erin G., Guzelian, Philip S.
Published in Proceedings of the National Academy of Sciences - PNAS (15.03.1992)
Published in Proceedings of the National Academy of Sciences - PNAS (15.03.1992)
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Complete cDNA Sequence of a Cytochrome P-450 Inducible by Glucocorticoids in Human Liver
Molowa, D. T., Schuetz, E. G., Wrighton, S. A., Watkins, P. B., Kremers, P., Mendez-Picon, G., Parker, G. A., Guzelian, P. S.
Published in Proceedings of the National Academy of Sciences - PNAS (01.07.1986)
Published in Proceedings of the National Academy of Sciences - PNAS (01.07.1986)
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Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR
Xie, W, Barwick, J L, Simon, C M, Pierce, A M, Safe, S, Blumberg, B, Guzelian, P S, Evans, R M
Published in Genes & development (01.12.2000)
Published in Genes & development (01.12.2000)
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