Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6
Guye, Patrick, Ebrahimkhani, Mohammad R, Kipniss, Nathan, Velazquez, Jeremy J, Schoenfeld, Eldi, Kiani, Samira, Griffith, Linda G, Weiss, Ron
Published in Nature communications (06.01.2016)
Published in Nature communications (06.01.2016)
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Journal Article
Rapid neurogenesis through transcriptional activation in human stem cells
Busskamp, Volker, Lewis, Nathan E, Guye, Patrick, Ng, Alex HM, Shipman, Seth L, Byrne, Susan M, Sanjana, Neville E, Murn, Jernej, Li, Yinqing, Li, Shangzhong, Stadler, Michael, Weiss, Ron, Church, George M
Published in Molecular systems biology (01.11.2014)
Published in Molecular systems biology (01.11.2014)
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Journal Article
Comparing in vitro human liver models to in vivo human liver using RNA-Seq
Gupta, Rajinder, Schrooders, Yannick, Hauser, Duncan, van Herwijnen, Marcel, Albrecht, Wiebke, ter Braak, Bas, Brecklinghaus, Tim, Castell, Jose V., Elenschneider, Leroy, Escher, Sylvia, Guye, Patrick, Hengstler, Jan G., Ghallab, Ahmed, Hansen, Tanja, Leist, Marcel, Maclennan, Richard, Moritz, Wolfgang, Tolosa, Laia, Tricot, Tine, Verfaillie, Catherine, Walker, Paul, van de Water, Bob, Kleinjans, Jos, Caiment, Florian
Published in Archives of toxicology (01.02.2021)
Published in Archives of toxicology (01.02.2021)
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Journal Article
Host cell interactome of tyrosine-phosphorylated bacterial proteins
Selbach, Matthias, Paul, Florian Ernst, Brandt, Sabine, Guye, Patrick, Daumke, Oliver, Backert, Steffen, Dehio, Christoph, Mann, Matthias
Published in Cell host & microbe (23.04.2009)
Published in Cell host & microbe (23.04.2009)
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Journal Article
Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes
Bhatt, Shweta, Gupta, Manoj K., Khamaisi, Mogher, Martinez, Rachael, Gritsenko, Marina A., Wagner, Bridget K., Guye, Patrick, Busskamp, Volker, Shirakawa, Jun, Wu, Gongxiong, Liew, Chong Wee, Clauss, Therese R., Valdez, Ivan, El Ouaamari, Abdelfattah, Dirice, Ercument, Takatani, Tomozumi, Keenan, Hillary A., Smith, Richard D., Church, George, Weiss, Ron, Wagers, Amy J., Qian, Wei-Jun, King, George L., Kulkarni, Rohit N.
Published in Cell metabolism (04.08.2015)
Published in Cell metabolism (04.08.2015)
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Journal Article
A translocated effector required for Bartonella dissemination from derma to blood safeguards migratory host cells from damage by co-translocated effectors
Okujava, Rusudan, Guye, Patrick, Lu, Yun-Yueh, Mistl, Claudia, Polus, Florine, Vayssier-Taussat, Muriel, Halin, Cornelia, Rolink, Antonius G, Dehio, Christoph
Published in PLoS pathogens (01.06.2014)
Published in PLoS pathogens (01.06.2014)
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Journal Article
Design and connection of robust genetic circuits
Randall, Adrian, Guye, Patrick, Gupta, Saurabh, Duportet, Xavier, Weiss, Ron
Published in Methods in enzymology (2011)
Published in Methods in enzymology (2011)
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Journal Article
A Bipartite Signal Mediates the Transfer of Type IV Secretion Substrates of Bartonella henselae into Human Cells
Schulein, Ralf, Guye, Patrick, Rhomberg, Thomas A., Schmid, Michael C., Schröder, Gunnar, Vergunst, Annette C., Carena, Ilaria, Dehio, Christoph, Falkow, Stanley
Published in Proceedings of the National Academy of Sciences - PNAS (18.01.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (18.01.2005)
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Journal Article
A translocated bacterial protein protects vascular endothelial cells from apoptosis
Schmid, Michael C, Scheidegger, Florine, Dehio, Michaela, Balmelle-Devaux, Nadège, Schulein, Ralf, Guye, Patrick, Chennakesava, Cuddapah S, Biedermann, Barbara, Dehio, Christoph
Published in PLoS pathogens (01.11.2006)
Published in PLoS pathogens (01.11.2006)
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Journal Article
Synthetic Morphogenesis
Teague, Brian P, Guye, Patrick, Weiss, Ron
Published in Cold Spring Harbor perspectives in biology (01.09.2016)
Published in Cold Spring Harbor perspectives in biology (01.09.2016)
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Journal Article
Rapid, modular and reliable construction of complex mammalian gene circuits
Guye, Patrick, Li, Yinqing, Wroblewska, Liliana, Duportet, Xavier, Weiss, Ron
Published in Nucleic acids research (01.09.2013)
Published in Nucleic acids research (01.09.2013)
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Journal Article
A platform for rapid prototyping of synthetic gene networks in mammalian cells
Duportet, Xavier, Wroblewska, Liliana, Guye, Patrick, Li, Yinqing, Eyquem, Justin, Rieders, Julianne, Rimchala, Tharathorn, Batt, Gregory, Weiss, Ron
Published in Nucleic acids research (01.12.2014)
Published in Nucleic acids research (01.12.2014)
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Journal Article
Abstract 52: PDX-derived 3D InSightTM tumor microtissues as ex-vivo human experimental models for evaluating therapeutic responses
Chiovaro, Francesca, Agarkova, Irina, Buschmann, Nicole, Pichon, Chloe', Langova, Teresa, Maier, Armin, Schueler, Julia, Guye, Patrick
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract LB-034: Development and characterization of PDX-derived 3D tumor microtissues as platform for screening targeted molecular therapeutics
Chiovaro, Francesca, Agarkova, Irina, Maier, Armin, Messner, Simon, Schueler, Julia, Guye, Patrick
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Fic domain‐catalyzed adenylylation: Insight provided by the structural analysis of the type IV secretion system effector BepA
Palanivelu, Dinesh V., Goepfert, Arnaud, Meury, Marcel, Guye, Patrick, Dehio, Christoph, Schirmer, Tilman
Published in Protein science (01.03.2011)
Published in Protein science (01.03.2011)
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A 3D Heterotypic Multicellular Tumor Spheroid Assay Platform to Discriminate Drug Effects on Stroma versus Cancer Cells
Weydert, Zoe, Lal-Nag, Madhu, Mathews-Greiner, Lesley, Thiel, Christoph, Cordes, Henrik, Küpfer, Lars, Guye, Patrick, Kelm, Jens M., Ferrer, Marc
Published in SLAS discovery (01.03.2020)
Published in SLAS discovery (01.03.2020)
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