Adult Human Primary Cardiomyocyte-Based Model for the Simultaneous Prediction of Drug-Induced Inotropic and Pro-arrhythmia Risk
Nguyen, Nathalie, Nguyen, William, Nguyenton, Brynna, Ratchada, Phachareeya, Page, Guy, Miller, Paul E, Ghetti, Andre, Abi-Gerges, Najah
Published in Frontiers in physiology (19.12.2017)
Published in Frontiers in physiology (19.12.2017)
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Quantitative Comparison of Effects of Dofetilide, Sotalol, Quinidine, and Verapamil between Human Ex vivo Trabeculae and In silico Ventricular Models Incorporating Inter-Individual Action Potential Variability
Britton, Oliver J, Abi-Gerges, Najah, Page, Guy, Ghetti, Andre, Miller, Paul E, Rodriguez, Blanca
Published in Frontiers in physiology (18.08.2017)
Published in Frontiers in physiology (18.08.2017)
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Arrhythmogenic and antiarrhythmic actions of late sustained sodium current in the adult human heart
Ton, Anh Tuan, Nguyen, William, Sweat, Katrina, Miron, Yannick, Hernandez, Eduardo, Wong, Tiara, Geft, Valentyna, Macias, Andrew, Espinoza, Ana, Truong, Ky, Rasoul, Lana, Stafford, Alexa, Cotta, Tamara, Mai, Christina, Indersmitten, Tim, Page, Guy, Miller, Paul E., Ghetti, Andre, Abi-Gerges, Najah
Published in Scientific reports (08.06.2021)
Published in Scientific reports (08.06.2021)
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Action Potential Recording and Pro-arrhythmia Risk Analysis in Human Ventricular Trabeculae
Qu, Yusheng, Page, Guy, Abi-Gerges, Najah, Miller, Paul E, Ghetti, Andre, Vargas, Hugo M
Published in Frontiers in physiology (05.01.2018)
Published in Frontiers in physiology (05.01.2018)
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Human ex-vivo action potential model for pro-arrhythmia risk assessment
Page, Guy, Ratchada, Phachareeya, Miron, Yannick, Steiner, Guido, Ghetti, Andre, Miller, Paul E., Reynolds, Jack A., Wang, Ken, Greiter-Wilke, Andrea, Polonchuk, Liudmila, Traebert, Martin, Gintant, Gary A., Abi-Gerges, Najah
Published in Journal of pharmacological and toxicological methods (01.09.2016)
Published in Journal of pharmacological and toxicological methods (01.09.2016)
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Late Sustained Sodium Current (INa,L) in Adult Human Primary Cardiomyocytes
Ton, Anh Tuan, Ghetti, Andrea, Page, Guy, Miller, Paul E., Abi Gerges, Najah
Published in Biophysical journal (07.02.2020)
Published in Biophysical journal (07.02.2020)
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α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABA B receptors
Castro, Joel, Harrington, Andrea M, Garcia-Caraballo, Sonia, Maddern, Jessica, Grundy, Luke, Zhang, Jingming, Page, Guy, Miller, Paul E, Craik, David J, Adams, David J, Brierley, Stuart M
Published in Gut (01.06.2017)
Published in Gut (01.06.2017)
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α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors
Castro, Joel, Harrington, Andrea M, Garcia-Caraballo, Sonia, Maddern, Jessica, Grundy, Luke, Zhang, Jingming, Page, Guy, Miller, Paul E, Craik, David J, Adams, David J, Brierley, Stuart M
Published in Gut (01.06.2017)
Published in Gut (01.06.2017)
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Measurement of Heart Contractility in Isolated Adult Human Primary Cardiomyocytes
Abi Gerges, Najah, Stafford, Alexa, Truong, Ky, Miron, Yannick, Winrow, Bryce, Krause, Brian, Page, Guy, Ghetti, Andre
Published in Journal of visualized experiments (09.08.2022)
Published in Journal of visualized experiments (09.08.2022)
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Journal Article
Late sustained sodium current in adult human primary cardiomyocytes
Ton, Anh Tuan, Ghetti, Andre, Page, Guy, Miller, Paul E., Abi-Gerges, Najah
Published in Journal of pharmacological and toxicological methods (01.09.2020)
Published in Journal of pharmacological and toxicological methods (01.09.2020)
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Journal Article
Multiparametric Mechanistic Profiling of Inotropic Drugs in Adult Human Primary Cardiomyocytes
Abi-Gerges, Najah, Indersmitten, Tim, Truong, Ky, Nguyen, William, Ratchada, Phachareeya, Nguyen, Nathalie, Page, Guy, Miller, Paul E., Ghetti, Andre
Published in Scientific reports (06.05.2020)
Published in Scientific reports (06.05.2020)
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Discovery and characterization of ORM‐11372, a novel inhibitor of the sodium‐calcium exchanger with positive inotropic activity
Otsomaa, Leena, Levijoki, Jouko, Wohlfahrt, Gerd, Chapman, Hugh, Koivisto, Ari‐Pekka, Syrjänen, Kaisa, Koskelainen, Tuula, Peltokorpi, Saara‐Elisa, Finckenberg, Piet, Heikkilä, Aira, Abi‐Gerges, Najah, Ghetti, Andre, Miller, Paul E., Page, Guy, Mervaala, Eero, Nagy, Norbert, Kohajda, Zsófia, Jost, Norbert, Virág, László, Varró, András, Papp, Julius Gy
Published in British journal of pharmacology (01.12.2020)
Published in British journal of pharmacology (01.12.2020)
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Action potential recordings and analysis in human ventricular trabeculae for assessment of pro-arrhythmic risk
Qu, Yusheng, Page, Guy, Abi-Gerges, Najah, Miller, Paul, Ghetti, Andre, Vargas, Hugo M.
Published in Journal of pharmacological and toxicological methods (01.09.2018)
Published in Journal of pharmacological and toxicological methods (01.09.2018)
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Predicting cardiotoxicity of cancer tyrosine kinase inhibitors with adult human primary cardiomyocytes
Abi-Gerges, Najah, Truong, Ky, Nguyen, William, Ratchada, Phachareeya, Indersmitten, Tim, Ton, Anh Tuan, Page, Guy, Miller, Paul E., Ghetti, Andre
Published in Journal of pharmacological and toxicological methods (01.09.2020)
Published in Journal of pharmacological and toxicological methods (01.09.2020)
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Human sensory neurons: Membrane properties and sensitization by inflammatory mediators
Davidson, Steve, Copits, Bryan A., Zhang, Jingming, Page, Guy, Ghetti, Andrea, Gereau, Robert W.
Published in Pain (Amsterdam) (01.09.2014)
Published in Pain (Amsterdam) (01.09.2014)
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Late sustained sodium current in the adult human heart
Ton, Anh Tuan, Nguyen, William, Miron, Yannick, Hernandez, Eduardo, Geft, Valentyna, Rasoul, Lana, Wong, Tiara, Indersmitten, Tim, Truong, Ky, Page, Guy, Miller, Paul E., Ghetti, Andre, Abi-Gerges, Najah
Published in Journal of pharmacological and toxicological methods (01.09.2021)
Published in Journal of pharmacological and toxicological methods (01.09.2021)
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Adult Human Primary Cardiomyocytes: An Integrative Translational Model for Preclinical Drug Testing
Nguyen, Nathalie, Miron, Yannick, Ratchada, Phachareeya, Page, Guy, Miller, Paul E., GHetti, Andre, Abi-Gerges, Najah
Published in Journal of pharmacological and toxicological methods (01.11.2017)
Published in Journal of pharmacological and toxicological methods (01.11.2017)
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Journal Article
[alpha]-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors
Castro, Joel, Harrington, Andrea M, Garcia-Caraballo, Sonia, Maddern, Jessica, Grundy, Luke, Zhang, Jingming, Page, Guy, Miller, Paul E, Craik, David J, Adams, David J, Brierley, Stuart M
Published in Gut (01.06.2017)
Published in Gut (01.06.2017)
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ミオシンモジュレーターの健常並びに不全ヒト心臓における収縮力及びCa2+トランジェントへの作用
Najah, Abi-Gerges, Katrina, Sweat, Ky, Truong, Alexa, Stafford, Yannick, Miron, Ana, Roup, Christina, Mai, 林, 隆志, Guy, Page, Andre, Ghetti
Published in 日本薬理学会年会要旨集 (2022)
Published in 日本薬理学会年会要旨集 (2022)
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Journal Article
Adult human primary cardiomyocyte model for the simultaneous prediction of drug-induced inotropic and pro-arrhythmia risk
Nguyen, Nathalie, Nguyen, William, Miron, Yannick, Ratchada, Phachareeya, Page, Guy, Miller, Paul, Ghetti, Andre, Abi-Gerges, Najah
Published in Journal of pharmacological and toxicological methods (01.09.2018)
Published in Journal of pharmacological and toxicological methods (01.09.2018)
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