Connexin-43 prevents hematopoietic stem cell senescence through transfer of reactive oxygen species to bone marrow stromal cells
Ishikawa, Eri Taniguchi, Gonzalez-Nieto, Daniel, Ghiaur, Gabriel, Dunn, Susan K., Ficker, Ashley M., Murali, Bhuvana, Madhu, Malav, Gutstein, David E., Fishman, Glenn I., Barrio, Luis C., Cancelas, Jose A.
Published in Proceedings of the National Academy of Sciences - PNAS (05.06.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (05.06.2012)
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Journal Article
Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects
Millar, John S, Reyes-Soffer, Gissette, Jumes, Patricia, Dunbar, Richard L, deGoma, Emil M, Baer, Amanda L, Karmally, Wahida, Donovan, Daniel S, Rafeek, Hashmi, Pollan, Laura, Tohyama, Junichiro, Johnson-Levonas, Amy O, Wagner, John A, Holleran, Stephen, Obunike, Joseph, Liu, Yang, Ramakrishnan, Rajasekhar, Lassman, Michael E, Gutstein, David E, Ginsberg, Henry N, Rader, Daniel J
Published in The Journal of clinical investigation (01.06.2015)
Published in The Journal of clinical investigation (01.06.2015)
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Journal Article
Relaxin and Matrix Metalloproteinase-9 in Angiotensin II-Induced Abdominal Aortic Aneurysms
Howatt, Deborah A., Dajee, Maya, Xie, Xiaojie, Moorleghen, Jessica, Rateri, Debra L., Balakrishnan, Anju, Cunha, Valdeci Da, Johns, Douglas G., Gutstein, David E., Daugherty, Alan, Lu, Hong
Published in Circulation Journal (2017)
Published in Circulation Journal (2017)
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Journal Article
Connexin-43 in the osteogenic BM niche regulates its cellular composition and the bidirectional traffic of hematopoietic stem cells and progenitors
Gonzalez-Nieto, Daniel, Li, Lina, Kohler, Anja, Ghiaur, Gabriel, Ishikawa, Eri, Sengupta, Amitava, Madhu, Malav, Arnett, Jorden L., Santho, Rebecca A., Dunn, Susan K., Fishman, Glenn I., Gutstein, David E., Civitelli, Roberto, Barrio, Luis C., Gunzer, Matthias, Cancelas, Jose A.
Published in Blood (31.05.2012)
Published in Blood (31.05.2012)
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Journal Article
Proliferation of Adult Sertoli Cells Following Conditional Knockout of the Gap Junctional Protein GJA1 (Connexin 43) in Mice
Sridharan, Santhi, Simon, Liz, Meling, Daryl D, Cyr, Daniel G, Gutstein, David E, Fishman, Glenn I, Guillou, Florian, Cooke, Paul S
Published in Biology of reproduction (01.05.2007)
Published in Biology of reproduction (01.05.2007)
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Journal Article
Gap junction communication between uterine stromal cells plays a critical role in pregnancy-associated neovascularization and embryo survival
Laws, Mary J, Taylor, Robert N, Sidell, Neil, DeMayo, Francesco J, Lydon, John P, Gutstein, David E, Bagchi, Milan K, Bagchi, Indrani C
Published in Development (Cambridge) (01.08.2008)
Published in Development (Cambridge) (01.08.2008)
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Journal Article
Modulation of Cardiac Gap Junction Expression and Arrhythmic Susceptibility
Danik, Stephan B, Liu, Fangyu, Zhang, Jie, Suk, H Jacqueline, Morley, Gregory E, Fishman, Glenn I, Gutstein, David E
Published in Circulation research (12.11.2004)
Published in Circulation research (12.11.2004)
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Journal Article
Effects of CETP inhibition with anacetrapib on metabolism of VLDL-TG and plasma apolipoproteins C-II, C-III, and E[S]
Millar, John S., Lassman, Michael E., Thomas, Tiffany, Ramakrishnan, Rajasekhar, Jumes, Patricia, Dunbar, Richard L., deGoma, Emil M., Baer, Amanda L., Karmally, Wahida, Donovan, Daniel S., Rafeek, Hashmi, Wagner, John A., Holleran, Stephen, Obunike, Joseph, Liu, Yang, Aoujil, Soumia, Standiford, Taylor, Gutstein, David E., Ginsberg, Henry N., Rader, Daniel J., Reyes-Soffer, Gissette
Published in Journal of lipid research (01.06.2017)
Published in Journal of lipid research (01.06.2017)
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Journal Article
The evaluation and management of drug effects on cardiac conduction (PR and QRS Intervals) in clinical development
Nada, Adel, MD, MS, MFPM, Gintant, Gary A., PhD, Kleiman, Robert, MD, Gutstein, David E., MD, Gottfridsson, Christer, MD, PhD, Michelson, Eric L., MD, Strnadova, Colette, PhD, Killeen, Matthew, MD, Geiger, Mary Jane, MD, PhD, Fiszman, Mónica L., MD, PhD, Koplowitz, Luana Pesco, MD, Carlson, Glenn F., MD, Rodriguez, Ignacio, MD, Sager, Philip T., MD
Published in The American heart journal (01.04.2013)
Published in The American heart journal (01.04.2013)
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Journal Article
Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC/MS/MS[S]
Pan, Yi, Zhou, Haihong, Mahsut, Ablatt, Rohm, Rory J., Berejnaia, Olga, Price, Olga, Chen, Ying, Castro-Perez, Jose, Lassman, Michael E., McLaren, David, Conway, James, Jensen, Kristian K., Thomas, Tiffany, Reyes-Soffer, Gissette, Ginsberg, Henry N., Gutstein, David E., Cleary, Michele, Previs, Stephen F., Roddy, Thomas P.
Published in Journal of lipid research (01.06.2014)
Published in Journal of lipid research (01.06.2014)
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Journal Article
CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis
Gillmore, Julian D, Gane, Ed, Taubel, Jorg, Kao, Justin, Fontana, Marianna, Maitland, Michael L, Seitzer, Jessica, O’Connell, Daniel, Walsh, Kathryn R, Wood, Kristy, Phillips, Jonathan, Xu, Yuanxin, Amaral, Adam, Boyd, Adam P, Cehelsky, Jeffrey E, McKee, Mark D, Schiermeier, Andrew, Harari, Olivier, Murphy, Andrew, Kyratsous, Christos A, Zambrowicz, Brian, Soltys, Randy, Gutstein, David E, Leonard, John, Sepp-Lorenzino, Laura, Lebwohl, David
Published in The New England journal of medicine (05.08.2021)
Published in The New England journal of medicine (05.08.2021)
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Journal Article
Connexin40 Imparts Conduction Heterogeneity to Atrial Tissue
Leaf, David E, Feig, Jonathan E, Vasquez, Carolina, Riva, Pamela L, Yu, Cindy, Lader, Joshua M, Kontogeorgis, Andrianos, Baron, Elvera L, Peters, Nicholas S, Fisher, Edward A, Gutstein, David E, Morley, Gregory E
Published in Circulation research (24.10.2008)
Published in Circulation research (24.10.2008)
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Journal Article
Discovery and Clinical Evaluation of MK‐8150, A Novel Nitric Oxide Donor With a Unique Mechanism of Nitric Oxide Release
Knox, Clayton D., Kam, Pieter‐Jan, Azer, Karim, Wong, Peggy, Ederveen, Antwan G., Shevell, Diane, Morabito, Christopher, Meehan, Alan G., Liu, Wen, Reynders, Tom, Denef, Jean Francois, Mitselos, Anna, Jonathan, Daniel, Gutstein, David E., Mitra, Kaushik, Sun, Shu Yu, Lo, Michael Man‐Chu, Cully, Doris, Ali, Amjad
Published in Journal of the American Heart Association (01.09.2016)
Published in Journal of the American Heart Association (01.09.2016)
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Journal Article
Cardiac imaging approaches to evaluate drug-induced myocardial dysfunction
Christian, Jennifer B., PharmD, MPH, PhD, Finkle, John K., MD, Ky, Bonnie, MD, Douglas, Pamela S., MD, Gutstein, David E., MD, Hockings, Paul D., PhD, Lainee, Pierre, DVM, PhD, Lenihan, Daniel J., MD, Mason, Jay W., MD, Sager, Philip T., MD, Todaro, Thomas G., MD, JD, Hicks, Karen A., MD, Kane, Robert C., MD, Ko, Hon-Sum, MD, Lindenfeld, JoAnn, MD, Michelson, Eric L., MD, Milligan, James, MB, ChB, Munley, Jiefen Y., MD, Raichlen, Joel S., MD, Shahlaee, Amir, MD, Strnadova, Colette, PhD, Ye, Brenda, MD, Turner, J. Rick, PhD
Published in The American heart journal (01.12.2012)
Published in The American heart journal (01.12.2012)
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Journal Article
Heterogeneous expression of gap junction channels in the heart leads to conduction defects and ventricular dysfunction
GUTSTEIN, David E, MORLEY, Gregory E, VAIDYA, Dhananjay, LIU, Fangyu, CHEN, Franklin L, STUHLMANN, Heidi, FISHMAN, Glenn I
Published in Circulation (New York, N.Y.) (04.09.2001)
Published in Circulation (New York, N.Y.) (04.09.2001)
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Journal Article
Reduced Intercellular Coupling Leads to Paradoxical Propagation across the Purkinje-Ventricular Junction and Aberrant Myocardial Activation
Morley, Gregory E., Danik, Stephan B., Bernstein, Scott, Sun, Yanjie, Rosner, Gregg, Gutstein, David E., Fishman, Glenn I., Peskin, Charles S.
Published in Proceedings of the National Academy of Sciences - PNAS (15.03.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (15.03.2005)
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Journal Article
Cell Coupling Between Ventricular Myocyte Pairs From Connexin43-Deficient Murine Hearts
Yao, Jian-An, Gutstein, David E, Liu, Fangyu, Fishman, Glenn I, Wit, Andrew L
Published in Circulation research (17.10.2003)
Published in Circulation research (17.10.2003)
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Journal Article
CETP (Cholesteryl Ester Transfer Protein) Inhibition With Anacetrapib Decreases Production of Lipoprotein(a) in Mildly Hypercholesterolemic Subjects
Thomas, Tiffany, Zhou, Haihong, Karmally, Wahida, Ramakrishnan, Rajasekhar, Holleran, Stephen, Liu, Yang, Jumes, Patricia, Wagner, John A, Hubbard, Brian, Previs, Stephen F, Roddy, Thomas, Johnson-Levonas, Amy O, Gutstein, David E, Marcovina, Santica M, Rader, Daniel J, Ginsberg, Henry N, Millar, John S, Reyes-Soffer, Gissette
Published in Arteriosclerosis, thrombosis, and vascular biology (01.09.2017)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.09.2017)
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