Identification of a Novel Delta Opioid Receptor Agonist Chemotype with Potential Negative Allosteric Modulator Capabilities
Meqbil, Yazan J, Su, Hongyu, Cassell, Robert J, Mores, Kendall L, Gutridge, Anna M, Cummins, Benjamin R, Chen, Lan, van Rijn, Richard M
Published in Molecules (Basel, Switzerland) (29.11.2021)
Published in Molecules (Basel, Switzerland) (29.11.2021)
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Evaluation of Kratom Opioid Derivatives as Potential Treatment Option for Alcohol Use Disorder
Gutridge, Anna M., Chakraborty, Soumen, Varga, Balazs R., Rhoda, Elizabeth S., French, Alexander R., Blaine, Arryn T., Royer, Quinten H., Cui, Haoyue, Yuan, Jinling, Cassell, Robert J., Szabó, Márk, Majumdar, Susruta, van Rijn, Richard M.
Published in Frontiers in pharmacology (03.11.2021)
Published in Frontiers in pharmacology (03.11.2021)
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G protein‐biased kratom‐alkaloids and synthetic carfentanil‐amide opioids as potential treatments for alcohol use disorder
Gutridge, Anna M., Robins, Meridith T., Cassell, Robert J., Uprety, Rajendra, Mores, Kendall L., Ko, Mee Jung, Pasternak, Gavril W., Majumdar, Susruta, Rijn, Richard M.
Published in British journal of pharmacology (01.04.2020)
Published in British journal of pharmacology (01.04.2020)
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β-Arrestin-dependent ERK signaling reduces anxiety-like and conditioned fear-related behaviors in mice
Ko, Mee Jung, Chiang, Terrance, Mukadam, Arbaaz A, Mulia, Grace E, Gutridge, Anna M, Lin, Angel, Chester, Julia A, van Rijn, Richard M
Published in Science signaling (03.08.2021)
Published in Science signaling (03.08.2021)
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A Novel Mitragynine Analog with Low-Efficacy Mu Opioid Receptor Agonism Displays Antinociception with Attenuated Adverse Effects
Chakraborty, Soumen, DiBerto, Jeffrey F, Faouzi, Abdelfattah, Bernhard, Sarah M, Gutridge, Anna M, Ramsey, Steven, Zhou, Yuchen, Provasi, Davide, Nuthikattu, Nitin, Jilakara, Rahul, Nelson, Melissa N. F, Asher, Wesley B, Eans, Shainnel O, Wilson, Lisa L, Chintala, Satyanarayana M, Filizola, Marta, van Rijn, Richard M, Margolis, Elyssa B, Roth, Bryan L, McLaughlin, Jay P, Che, Tao, Sames, Dalibor, Javitch, Jonathan A, Majumdar, Susruta
Published in Journal of medicinal chemistry (23.09.2021)
Published in Journal of medicinal chemistry (23.09.2021)
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Modified Akuamma Alkaloids with Increased Potency at the Mu-opioid Receptor
Hennessy, Madeline R., Gutridge, Anna M., French, Alexander R., Rhoda, Elizabeth S., Meqbil, Yazan J., Gill, Meghna, Kashyap, Yavnika, Appourchaux, Kevin, Paul, Barnali, Wang, Zaijie Jim, van Rijn, Richard M., Riley, Andrew P.
Published in Journal of medicinal chemistry (09.03.2023)
Published in Journal of medicinal chemistry (09.03.2023)
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Isolation and Pharmacological Characterization of Six Opioidergic Picralima nitida Alkaloids
Creed, Simone M, Gutridge, Anna M, Argade, Malaika D, Hennessy, Madeline R, Friesen, J. Brent, Pauli, Guido F, van Rijn, Richard M, Riley, Andrew P
Published in Journal of natural products (Washington, D.C.) (22.01.2021)
Published in Journal of natural products (Washington, D.C.) (22.01.2021)
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Journal Article
KRATOM OPIOID DERIVATIVES FOR THE TREATMENT OF ALCOHOL USE DISORDER
VAN RIJN, Richard M, SAMES, Dalibor, GUTRIDGE, Anna M, CHAKRABORTY, Soumen, MAJUMDAR, Susruta, VARGA, Balazs
Year of Publication 10.08.2023
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Year of Publication 10.08.2023
Patent
β-arrestin-dependent ERK signaling positively correlates with reduced anxiety-like and conditioned fear-related behavior in mice
Mee Jung Ko, Chiang, Terrance, Mukadam, Arbaaz A, Mulia, Grace E, Gutridge, Anna M, Lin, Angel, Chester, Julia A, Van Rijn, Richard M
Published in bioRxiv (10.04.2020)
Published in bioRxiv (10.04.2020)
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A novel mitragynine analog with low efficacy mu-opioid receptor agonism displays antinociception with attenuated adverse effects
Chakraborty, Soumen, Diberto, Jeffrey F, Abdelfattah Faouzi, Bernhard, Sarah M, Gutridge, Anna M, Ramsey, Steven, Zhou, Yuchen, Provasi, Davide, Nuthikattu, Nitin, Jilakara, Rahul, Nelson, Melissa, Asher, Wesley B, Eans, Shainnel O, Wilson, Lisa L, Chintala, Satyanarayana M, Filizola, Marta, Van Rijn, Richard M, Margolis, Elyssa B, Roth, Bryan L, Mclaughlin, Jay P, Javitch, Jonathan A, Che, Tao, Majumdar, Susruta
Published in bioRxiv (22.04.2021)
Published in bioRxiv (22.04.2021)
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