Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer’s disease
Portelius, Erik, Bogdanovic, Nenad, Gustavsson, Mikael K., Volkmann, Inga, Brinkmalm, Gunnar, Zetterberg, Henrik, Winblad, Bengt, Blennow, Kaj
Published in Acta neuropathologica (01.08.2010)
Published in Acta neuropathologica (01.08.2010)
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Journal Article
SILAC zebrafish for quantitative analysis of protein turnover and tissue regeneration
Westman-Brinkmalm, Ann, Abramsson, Alexandra, Pannee, Josef, Gang, Chen, Gustavsson, Mikael K., von Otter, Malin, Blennow, Kaj, Brinkmalm, Gunnar, Heumann, Hermann, Zetterberg, Henrik
Published in Journal of proteomics (21.12.2011)
Published in Journal of proteomics (21.12.2011)
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Journal Article
Distinct cerebrospinal fluid amyloid beta peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer's disease
Portelius, Erik, Andreasson, Ulf, Ringman, John M, Buerger, Katharina, Daborg, Jonny, Buchhave, Peder, Hansson, Oskar, Harmsen, Andreas, Gustavsson, Mikael K, Hanse, Eric, Galasko, Douglas, Hampel, Harald, Blennow, Kaj, Zetterberg, Henrik
Published in Molecular neurodegeneration (14.01.2010)
Published in Molecular neurodegeneration (14.01.2010)
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Journal Article
Pyroglutamate Amyloid β (Aβ) Aggravates Behavioral Deficits in Transgenic Amyloid Mouse Model for Alzheimer Disease
Wittnam, Jessica L., Portelius, Erik, Zetterberg, Henrik, Gustavsson, Mikael K., Schilling, Stephan, Koch, Birgit, Demuth, Hans-Ulrich, Blennow, Kaj, Wirths, Oliver, Bayer, Thomas A.
Published in The Journal of biological chemistry (09.03.2012)
Published in The Journal of biological chemistry (09.03.2012)
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Journal Article
Cerebrospinal fluid biomarkers of β-amyloid metabolism in multiple sclerosis
Augutis, Kristin, Axelsson, Markus, Portelius, Erik, Brinkmalm, Gunnar, Andreasson, Ulf, Gustavsson, Mikael K, Malmeström, Clas, Lycke, Jan, Blennow, Kaj, Zetterberg, Henrik, Mattsson, Niklas
Published in Multiple sclerosis (01.04.2013)
Published in Multiple sclerosis (01.04.2013)
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Journal Article
An online nano-LC-ESI-FTICR-MS method for comprehensive characterization of endogenous fragments from amyloid β and amyloid precursor protein in human and cat cerebrospinal fluid
Brinkmalm, Gunnar, Portelius, Erik, Öhrfelt, Annika, Mattsson, Niklas, Persson, Rita, Gustavsson, Mikael K., Vite, Charles H., Gobom, Johan, Månsson, Jan-Eric, Nilsson, Jonas, Halim, Adnan, Larson, Göran, Rüetschi, Ulla, Zetterberg, Henrik, Blennow, Kaj, Brinkmalm, Ann
Published in Journal of mass spectrometry. (01.05.2012)
Published in Journal of mass spectrometry. (01.05.2012)
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Journal Article
Acute Effect on the Aβ Isoform Pattern in CSF in Response to γ-Secretase Modulator and Inhibitor Treatment in Dogs
Portelius, Erik, Van Broeck, Bianca, Andreasson, Ulf, Gustavsson, Mikael K., Mercken, Marc, Zetterberg, Henrik, Borghys, Herman, Blennow, Kaj
Published in Journal of Alzheimer's disease (01.01.2010)
Published in Journal of Alzheimer's disease (01.01.2010)
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Journal Article
Distinct cerebrospinal fluid amyloid [beta] peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer's disease
Portelius, Erik, Andreasson, Ulf, Ringman, John M, Buerger, Katharina, Daborg, Jonny, Buchhave, Peder, Hansson, Oskar, Harmsen, Andreas, Gustavsson, Mikael K, Hanse, Eric, Galasko, Douglas, Hampel, Harald, Blennow, Kaj, Zetterberg, Henrik
Published in Molecular neurodegeneration (14.01.2010)
Published in Molecular neurodegeneration (14.01.2010)
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Journal Article
Evaluation of the Performance of Novel Aβ Isoforms as Theragnostic Markers in Alzheimer’s Disease: From the Cell to the Patient
Portelius, Erik, Gustavsson, Mikael K., Zetterberg, Henrik, Andreasson, Ulf, Blennow, Kaj
Published in Neuro-degenerative diseases (01.01.2012)
Published in Neuro-degenerative diseases (01.01.2012)
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Journal Article
Amyloid-β metabolism in Niemann-Pick C disease models and patients
Mattsson, Niklas, Olsson, Maria, Gustavsson, Mikael K., Kosicek, Marko, Malnar, Martina, Månsson, Jan-Eric, Blomqvist, Maria, Gobom, Johan, Andreasson, Ulf, Brinkmalm, Gunnar, Vite, Charles, Hecimovic, Silva, Hastings, Caroline, Blennow, Kaj, Zetterberg, Henrik, Portelius, Erik
Published in Metabolic brain disease (01.12.2012)
Published in Metabolic brain disease (01.12.2012)
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Journal Article
The amyloid-β isoform pattern in cerebrospinal fluid in familial PSEN1 M139T- and L286P-associated Alzheimer's disease
PORTELIUS, ERIK, FORTEA, JUAN, MOLINUEVO, JOSE LUIS, GUSTAVSSON, MIKAEL K, ANDREASSON, ULF, SANCHEZ-VALLE, RAQUEL
Published in Molecular medicine reports (01.04.2012)
Published in Molecular medicine reports (01.04.2012)
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Journal Article
Characterization of the Brain β-Amyloid Isoform Pattern at Different Ages of Tg2576 Mice
Mustafiz, Tamanna, Portelius, Erik, Gustavsson, Mikael K., Hölttä, Mikko, Zetterberg, Henrik, Blennow, Kaj, Nordberg, Agneta, Unger Lithner, Christina
Published in Neuro-degenerative diseases (01.01.2011)
Published in Neuro-degenerative diseases (01.01.2011)
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Journal Article
Effects of γ-Secretase Inhibition on the Amyloid β Isoform Pattern in a Mouse Model of Alzheimer’s Disease
Portelius, Erik, Zhang, Bin, Gustavsson, Mikael K., Brinkmalm, Gunnar, Westman-Brinkmalm, Ann, Zetterberg, Henrik, Lee, Virginia M.-Y., Trojanowski, John Q., Blennow, Kaj
Published in Neuro-degenerative diseases (01.01.2009)
Published in Neuro-degenerative diseases (01.01.2009)
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Journal Article
Acute effect on novel Abeta isoforms in cerebrospinal fluid as a response to treatment with gamma-secretase inhibitors and modulators in Alzheimer's disease
Portelius, Erik, Dean, Robert A, Van Broeck, Bianca, Gustavsson, Mikael K, Mercen, Marc, Anderasson, Ulf, Zetterberg, Henrik, Borghys, Herman, Siemers, Eric, Blennow, Kaj
Published in Alzheimer's & dementia (01.07.2010)
Published in Alzheimer's & dementia (01.07.2010)
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Journal Article
Longitudinal cerebrospinal fluid biomarkers over four years in mild cognitive impairment
Mattsson, Niklas, Portelius, Erik, Rolstad, Sindre, Gustavsson, Mikael, Andreasson, Ulf, Stridsberg, Mats, Wallin, Anders, Blennow, Kaj, Zetterberg, Henrik
Published in Journal of Alzheimer's disease (01.01.2012)
Published in Journal of Alzheimer's disease (01.01.2012)
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Journal Article
BACE1 inhibition induces a specific cerebrospinal fluid β-amyloid pattern that identifies drug effects in the central nervous system
Mattsson, Niklas, Rajendran, Lawrence, Zetterberg, Henrik, Gustavsson, Mikael, Andreasson, Ulf, Olsson, Maria, Brinkmalm, Gunnar, Lundkvist, Johan, Jacobson, Laura H, Perrot, Ludovic, Neumann, Ulf, Borghys, Herman, Mercken, Marc, Dhuyvetter, Deborah, Jeppsson, Fredrik, Blennow, Kaj, Portelius, Erik
Published in PloS one (06.02.2012)
Published in PloS one (06.02.2012)
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Journal Article
Evaluation of the Performance of Novel A[beta] Isoforms as Theragnostic Markers in Alzheimer's Disease: From the Cell to the Patient
Portelius, Erik, Gustavsson, Mikael K, Zetterberg, Henrik, Andreasson, Ulf, Blennow, Kaj
Published in Neuro-degenerative diseases (01.04.2012)
Published in Neuro-degenerative diseases (01.04.2012)
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Journal Article
An online nano-LC-ESI-FTICR-MS method for comprehensive characterization of endogenous fragments from amyloid [beta] and amyloid precursor protein in human and cat cerebrospinal fluid
Brinkmalm, Gunnar, Portelius, Erik, Öhrfelt, Annika, Mattsson, Niklas, Persson, Rita, Gustavsson, Mikael K, Vite, Charles H, Gobom, Johan, Månsson, Jan-Eric, Nilsson, Jonas, Halim, Adnan, Larson, Göran, Rüetschi, Ulla, Zetterberg, Henrik, Blennow, Kaj, Brinkmalm, Ann
Published in Journal of mass spectrometry. (01.05.2012)
Published in Journal of mass spectrometry. (01.05.2012)
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Journal Article
Amyloid-[beta] metabolism in Niemann-Pick C disease models and patients
Mattsson, Niklas, Olsson, Maria, Gustavsson, Mikael K, Kosicek, Marko, Malnar, Martina, Månsson, Jan-eric, Blomqvist, Maria, Gobom, Johan, Andreasson, Ulf, Brinkmalm, Gunnar, Vite, Charles, Hecimovic, Silva, Hastings, Caroline, Blennow, Kaj, Zetterberg, Henrik, Portelius, Erik
Published in Metabolic brain disease (01.12.2012)
Published in Metabolic brain disease (01.12.2012)
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Journal Article