The JAK/STAT pathway in obesity and diabetes
Gurzov, Esteban N., Stanley, William J., Pappas, Evan G., Thomas, Helen E., Gough, Daniel J.
Published in The FEBS journal (01.08.2016)
Published in The FEBS journal (01.08.2016)
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Journal Article
Hepatic Oxidative Stress Promotes Insulin-STAT-5 Signaling and Obesity by Inactivating Protein Tyrosine Phosphatase N2
Gurzov, Esteban N., Tran, Melanie, Fernandez-Rojo, Manuel A., Merry, Troy L., Zhang, Xinmei, Xu, Yang, Fukushima, Atsushi, Waters, Michael J., Watt, Matthew J., Andrikopoulos, Sofianos, Neel, Benjamin G., Tiganis, Tony
Published in Cell metabolism (01.07.2014)
Published in Cell metabolism (01.07.2014)
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Journal Article
Protein tyrosine phosphatases: molecular switches in metabolism and diabetes
Gurzov, Esteban N, Stanley, William J, Brodnicki, Thomas C, Thomas, Helen E
Published in Trends in endocrinology and metabolism (01.01.2015)
Published in Trends in endocrinology and metabolism (01.01.2015)
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Journal Article
Glucagon-Like Peptide-1 Agonists Protect Pancreatic β-Cells From Lipotoxic Endoplasmic Reticulum Stress Through Upregulation of BiP and JunB
CUNHA, Daniel A, LADRIERE, Laurence, ORTIS, Fernanda, IGOILLO-ESTEVE, Mariana, GURZOV, Esteban N, LUPI, Roberto, MARCHETTI, Piero, EIZIRIK, Décio L, CNOP, Miriam
Published in Diabetes (New York, N.Y.) (01.12.2009)
Published in Diabetes (New York, N.Y.) (01.12.2009)
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Journal Article
Metabolite-based dietary supplementation in human type 1 diabetes is associated with microbiota and immune modulation
Bell, Kirstine J, Saad, Sonia, Tillett, Bree J, McGuire, Helen M, Bordbar, Sara, Yap, Yu Anne, Nguyen, Long T, Wilkins, Marc R, Corley, Susan, Brodie, Shannon, Duong, Sussan, Wright, Courtney J, Twigg, Stephen, de St Groth, Barbara Fazekas, Harrison, Leonard C, Mackay, Charles R, Gurzov, Esteban N, Hamilton-Williams, Emma E, Mariño, Eliana
Published in Microbiome (19.01.2022)
Published in Microbiome (19.01.2022)
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Journal Article
TCPTP Regulates SFK and STAT3 Signaling and Is Lost in Triple-Negative Breast Cancers
Shields, Benjamin J., Wiede, Florian, Gurzov, Esteban N., Wee, Kenneth, Hauser, Christine, Zhu, Hong-Jian, Molloy, Timothy J., O'Toole, Sandra A., Daly, Roger J., Sutherland, Robert L., Mitchell, Christina A., McLean, Catriona A., Tiganis, Tony
Published in Molecular and Cellular Biology (01.02.2013)
Published in Molecular and Cellular Biology (01.02.2013)
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Journal Article
Nova1 or Bim Deficiency in Pancreatic β-Cells Does Not Alter Multiple Low-Dose Streptozotocin-Induced Diabetes and Diet-Induced Obesity in Mice
Brahma, Manoja K, Xiao, Peng, Popa, Madalina, Negueruela, Javier, Vandenbempt, Valerie, Demine, Stéphane, Cardozo, Alessandra K, Gurzov, Esteban N
Published in Nutrients (01.09.2022)
Published in Nutrients (01.09.2022)
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Journal Article
Protocol for CRISPR-Cas12a genome editing of protein tyrosine phosphatases in human pluripotent stem cells and functional β-like cell generation
Negueruela, Javier, Vandenbempt, Valerie, Talamantes, Stephanie, Ribeiro-Costa, Francisco, Nunes, Mariana, Dias, André, Bansal, Mayank, Gurzov, Esteban N.
Published in STAR protocols (20.09.2024)
Published in STAR protocols (20.09.2024)
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Journal Article
Inhibition of Y1 receptor signaling improves islet transplant outcome
Loh, Kim, Shi, Yan-Chuan, Walters, Stacey, Bensellam, Mohammed, Lee, Kailun, Dezaki, Katsuya, Nakata, Masanori, Ip, Chi Kin, Chan, Jeng Yie, Gurzov, Esteban N., Thomas, Helen E., Waibel, Michaela, Cantley, James, Kay, Thomas W., Yada, Toshihiko, Laybutt, D. Ross, Grey, Shane T., Herzog, Herbert
Published in Nature communications (08.09.2017)
Published in Nature communications (08.09.2017)
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Journal Article
Inhibition of RIPK1 kinase does not affect diabetes development: β-Cells survive RIPK1 activation
Takiishi, Tatiana, Xiao, Peng, Franchimont, Marie, Gilglioni, Eduardo H., Arroba, Erick N., Gurzov, Esteban N., Bertrand, Mathieu JM, Cardozo, Alessandra K.
Published in Molecular metabolism (Germany) (01.03.2023)
Published in Molecular metabolism (Germany) (01.03.2023)
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Journal Article
Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance
Colli, Maikel L, Nogueira, Tatiane C, Allagnat, Florent, Cunha, Daniel A, Gurzov, Esteban N, Cardozo, Alessandra K, Roivainen, Merja, Op de Beeck, Anne, Eizirik, Decio L
Published in PLoS pathogens (01.09.2011)
Published in PLoS pathogens (01.09.2011)
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Journal Article
The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells
Moore, Fabrice, Santin, Izortze, Nogueira, Tatiane C, Gurzov, Esteban N, Marselli, Lorella, Marchetti, Piero, Eizirik, Decio L
Published in PloS one (08.02.2012)
Published in PloS one (08.02.2012)
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Journal Article
JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells
Gurzov, Esteban N, Ortis, Fernanda, Bakiri, Latifa, Wagner, Erwin F, Eizirik, Decio L
Published in PloS one (21.08.2008)
Published in PloS one (21.08.2008)
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Journal Article
HAMSAB diet ameliorates dysfunctional signaling in pancreatic islets in autoimmune diabetes
Vandenbempt, Valerie, Eski, Sema Elif, Brahma, Manoja K., Li, Ao, Negueruela, Javier, Bruggeman, Ylke, Demine, Stéphane, Xiao, Peng, Cardozo, Alessandra K., Baeyens, Nicolas, Martelotto, Luciano G., Singh, Sumeet Pal, Mariño, Eliana, Gysemans, Conny, Gurzov, Esteban N.
Published in iScience (19.01.2024)
Published in iScience (19.01.2024)
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Journal Article
Lipotoxic Stress Induces Pancreatic β-Cell Apoptosis through Modulation of Bcl-2 Proteins by the Ubiquitin-Proteasome System
Gurzov, Esteban N., Thomas, Helen E., Varanasi, L. Chitra, Stanley, William J., Saadi, Hamdi, Pappas, Evan G., Wali, Jibran A., Litwak, Sara A., Kay, Thomas W. H.
Published in Journal of Diabetes Research (01.01.2015)
Published in Journal of Diabetes Research (01.01.2015)
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Journal Article
Novel Strategies to Protect and Visualize Pancreatic β Cells in Diabetes
Gurzov, Esteban N., Ke, Pu Chun, Ahlgren, Ulf, Garcia Ribeiro, Rita S., Gotthardt, Martin
Published in Trends in endocrinology and metabolism (01.12.2020)
Published in Trends in endocrinology and metabolism (01.12.2020)
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Journal Article
Sweet Killing in Obesity and Diabetes: The Metabolic Role of the BH3-only Protein BIM
Miani, Michela, Elvira, Bernat, Gurzov, Esteban N.
Published in Journal of molecular biology (14.09.2018)
Published in Journal of molecular biology (14.09.2018)
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