Dasatinib loaded mucoadhesive lecithin-chitosan hybrid nanoparticles for its augmented oral delivery, in-vitro efficacy and safety
Mehandole, Arti, Mahajan, Srushti, Aalhate, Mayur, Kumar, Rahul, Maji, Indrani, Gupta, Ujala, Kumar Guru, Santosh, Kumar Singh, Pankaj
Published in International journal of pharmaceutics (15.02.2024)
Published in International journal of pharmaceutics (15.02.2024)
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Journal Article
New cycloartane triterpenoids from Dysoxylum malabaricum and their cytotoxic evaluation
Bhardwaj, Nivedita, Sharma, Anamika, Tripathi, Nancy, Goel, Bharat, Ravikanth, G., Kumar Guru, Santosh, Jain, Shreyans K.
Published in Steroids (01.12.2023)
Published in Steroids (01.12.2023)
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Journal Article
Mechanism of kisspeptin neuron synchronization for pulsatile hormone secretion in male mice
Han, Su Young, Morris, Paul G., Kim, Jae-Chang, Guru, Santosh, Pardo-Navarro, Maria, Yeo, Shel-Hwa, McQuillan, H. James, Herbison, Allan E.
Published in Cell reports (Cambridge) (31.01.2023)
Published in Cell reports (Cambridge) (31.01.2023)
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Journal Article
VEGF-neuropilin-2 signaling promotes stem-like traits in breast cancer cells by TAZ-mediated repression of the Rac GAP β2-chimaerin
Elaimy, Ameer L, Guru, Santosh, Chang, Cheng, Ou, Jianhong, Amante, John J, Zhu, Lihua Julie, Goel, Hira Lal, Mercurio, Arthur M
Published in Science signaling (01.05.2018)
Published in Science signaling (01.05.2018)
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Journal Article
A novel triazole derivative of betulinic acid induces extrinsic and intrinsic apoptosis in human leukemia HL-60 cells
Khan, Imran, Guru, Santosh K., Rath, Santosh K., Chinthakindi, Praveen K., Singh, Buddh, Koul, Surrinder, Bhushan, Shashi, Sangwan, Payare L.
Published in European journal of medicinal chemistry (27.01.2016)
Published in European journal of medicinal chemistry (27.01.2016)
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Journal Article
Discovery of a marine-derived bis-indole alkaloid fascaplysin, as a new class of potent P-glycoprotein inducer and establishment of its structure–activity relationship
Manda, Sudhakar, Sharma, Sadhana, Wani, Abubakar, Joshi, Prashant, Kumar, Vikas, Guru, Santosh K., Bharate, Sonali S., Bhushan, Shashi, Vishwakarma, Ram A., Kumar, Ajay, Bharate, Sandip B.
Published in European journal of medicinal chemistry (01.01.2016)
Published in European journal of medicinal chemistry (01.01.2016)
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Journal Article
The synthetic tryptanthrin analogue suppresses STAT3 signaling and induces caspase dependent apoptosis via ERK up regulation in human leukemia HL-60 cells
Pathania, Anup S, Kumar, Suresh, Guru, Santosh K, Bhushan, Shashi, Sharma, Parduman R, Aithagani, Sravan K, Singh, Parvinder P, Vishwakarma, Ram A, Kumar, Ajay, Malik, Fayaz
Published in PloS one (10.11.2014)
Published in PloS one (10.11.2014)
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Journal Article
Discovery and Preclinical Development of IIIM-290, an Orally Active Potent Cyclin-Dependent Kinase Inhibitor
Bharate, Sandip B, Kumar, Vikas, Jain, Shreyans K, Mintoo, Mubashir J, Guru, Santosh K, Nuthakki, Vijay K, Sharma, Mohit, Bharate, Sonali S, Gandhi, Sumit G, Mondhe, Dilip M, Bhushan, Shashi, Vishwakarma, Ram A
Published in Journal of medicinal chemistry (22.02.2018)
Published in Journal of medicinal chemistry (22.02.2018)
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Journal Article
Accommodation of ring C expanded deoxyvasicinone in the HDAC inhibitory pharmacophore culminates into a tractable anti-lung cancer agent and pH-responsive nanocarrier
Sharma, Ram, Chatterjee, Esha, Mathew, Jacob, Sharma, Sachin, Rao, N. Vijayakameswara, Pan, Chun-Hsu, Lee, Sung-Bau, Dhingra, Ashwani, Grewal, Ajmer S., Liou, Jing Ping, Guru, Santosh K., Nepali, Kunal
Published in European journal of medicinal chemistry (05.10.2022)
Published in European journal of medicinal chemistry (05.10.2022)
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Journal Article
6-Aryl substituted 4-(4-cyanomethyl) phenylamino quinazolines as a new class of isoform-selective PI3K-alpha inhibitors
Yadav, Rammohan R., Guru, Santosh K., Joshi, Prashant, Mahajan, Girish, Mintoo, Mubashir J., Kumar, Vikas, Bharate, Sonali S., Mondhe, Dilip M., Vishwakarma, Ram A., Bhushan, Shashi, Bharate, Sandip B.
Published in European journal of medicinal chemistry (21.10.2016)
Published in European journal of medicinal chemistry (21.10.2016)
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Journal Article
IMP3 Stabilization of WNT5B mRNA Facilitates TAZ Activation in Breast Cancer
Samanta, Sanjoy, Guru, Santosh, Elaimy, Ameer L., Amante, John J., Ou, Jianhong, Yu, Jun, Zhu, Lihua J., Mercurio, Arthur M.
Published in Cell reports (Cambridge) (29.05.2018)
Published in Cell reports (Cambridge) (29.05.2018)
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Journal Article
Interplay between cell cycle and autophagy induced by boswellic acid analog
Pathania, Anup S, Guru, Santosh K, Kumar, Suresh, Kumar, Ashok, Ahmad, Masroor, Bhushan, Shashi, Sharma, Parduman R, Mahajan, Priya, Shah, Bhahwal A, Sharma, Simmi, Nargotra, Amit, Vishwakarma, Ram, Korkaya, Hasan, Malik, Fayaz
Published in Scientific reports (29.09.2016)
Published in Scientific reports (29.09.2016)
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Journal Article
Cytotoxicity and antimicrobial activity of the methanol extract and compounds from Polygonum limbatum
Dzoyem, Jean P, Nkuete, Antoine H L, Kuete, Victor, Tala, Michel F, Wabo, Hippolyte K, Guru, Santosh K, Rajput, Vikrant S, Sharma, Akash, Tane, Pierre, Khan, Inshad A, Saxena, Anil K, Laatsch, Hartmut, Tan, Ning-Hua
Published in Planta medica (01.05.2012)
Published in Planta medica (01.05.2012)
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Journal Article
A chromatography-free isolation of rohitukine from leaves of Dysoxylum binectariferum: Evaluation for in vitro cytotoxicity, Cdk inhibition and physicochemical properties
Kumar, Vikas, Guru, Santosh K., Jain, Shreyans K., Joshi, Prashant, Gandhi, Sumit G., Bharate, Sandip B., Bhushan, Shashi, Bharate, Sonali S., Vishwakarma, Ram A.
Published in Bioorganic & medicinal chemistry letters (01.08.2016)
Published in Bioorganic & medicinal chemistry letters (01.08.2016)
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Journal Article
Bioactive metabolites from an endophytic Cryptosporiopsis sp. inhabiting Clidemia hirta
Zilla, Mahesh K., Qadri, Masroor, Pathania, Anup S., Strobel, Gary A., Nalli, Yedukondalu, Kumar, Sunil, Guru, Santosh K., Bhushan, Shashi, Singh, Sanjay K., Vishwakarma, Ram A., Riyaz-Ul-Hassan, Syed, Ali, Asif
Published in Phytochemistry (Oxford) (01.11.2013)
Published in Phytochemistry (Oxford) (01.11.2013)
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Journal Article
Synthesis and anti-proliferative activities of new derivatives of embelin
Singh, Baljinder, Guru, Santosh K., Sharma, Rashmi, Bharate, Sonali S., Khan, Inshad Ali, Bhushan, Shashi, Bharate, Sandip B., Vishwakarma, Ram A.
Published in Bioorganic & medicinal chemistry letters (15.10.2014)
Published in Bioorganic & medicinal chemistry letters (15.10.2014)
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Journal Article
Bioassay-Guided Fractionation and Dereplication Studies of Sesame oil: Isolation of 8-Acetoxypinoresinol as an Anti-Proliferative Metabolite and Prediction of Target
Nalli, Yedu K., Guru, Santosh K., Jain, Priti, Mishra, Vishal, Jain, Shreyans K.
Published in National Academy of Sciences, India. Proceedings. Section B. Biological Sciences (01.09.2022)
Published in National Academy of Sciences, India. Proceedings. Section B. Biological Sciences (01.09.2022)
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Journal Article
Conference Proceeding
Pyrano-isochromanones as IL‑6 Inhibitors: Synthesis, in Vitro and in Vivo Antiarthritic Activity
Jain, Shreyans K, Singh, Surjeet, Khajuria, Anamika, Guru, Santosh K, Joshi, Prashant, Meena, Samdarshi, Nadkarni, Janhavi R, Singh, Amarinder, Bharate, Sonali S, Bhushan, Shashi, Bharate, Sandip B, Vishwakarma, Ram A
Published in Journal of medicinal chemistry (28.08.2014)
Published in Journal of medicinal chemistry (28.08.2014)
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Journal Article
3-(Benzo[d][1,3]dioxol-5-ylamino)-N-(4-fluorophenyl)thiophene-2-carboxamide overcomes cancer chemoresistance via inhibition of angiogenesis and P-glycoprotein efflux pump activity
Mudududdla, Ramesh, Guru, Santosh K., Wani, Abubakar, Sharma, Sadhana, Joshi, Prashant, Vishwakarma, Ram A., Kumar, Ajay, Bhushan, Shashi, Bharate, Sandip B.
Published in Organic & biomolecular chemistry (14.04.2015)
Published in Organic & biomolecular chemistry (14.04.2015)
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Journal Article
Colchicine derivatives with potent anticancer activity and reduced P-glycoprotein induction liability
Singh, Baljinder, Kumar, Ashok, Joshi, Prashant, Guru, Santosh K., Kumar, Suresh, Wani, Zahoor A., Mahajan, Girish, Hussain, Aashiq, Qazi, Asif Khurshid, Kumar, Ajay, Bharate, Sonali S., Gupta, Bishan D., Sharma, Parduman R., Hamid, Abid, Saxena, Ajit K., Mondhe, Dilip M., Bhushan, Shashi, Bharate, Sandip B., Vishwakarma, Ram A.
Published in Organic & biomolecular chemistry (28.05.2015)
Published in Organic & biomolecular chemistry (28.05.2015)
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Journal Article