Availability of evidence of benefits on overall survival and quality of life of cancer drugs approved by European Medicines Agency: retrospective cohort study of drug approvals 2009-13
Davis, Courtney, Naci, Huseyin, Gurpinar, Evrim, Poplavska, Elita, Pinto, Ashlyn, Aggarwal, Ajay
Published in BMJ (Online) (04.10.2017)
Published in BMJ (Online) (04.10.2017)
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NSAIDs Inhibit Tumorigenesis, but How?
GURPINAR, Evrim, GRIZZLE, William E, PIAZZA, Gary A
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Published in Clinical cancer research (01.03.2014)
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Preclinical pharmacology of BA-TPQ, a novel synthetic iminoquinone anticancer agent
Ezell, Scharri J, Li, Haibo, Xu, Hongxia, Zhang, Xiangrong, Gurpinar, Evrim, Zhang, Xu, Rayburn, Elizabeth R, Sommers, Charnell I, Yang, Xinyi, Velu, Sadanandan E, Wang, Wei, Zhang, Ruiwen
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Published in Marine drugs (13.07.2010)
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Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling
Li, Nan, Xi, Yaguang, Tinsley, Heather N, Gurpinar, Evrim, Gary, Bernard D, Zhu, Bing, Li, Yonghe, Chen, Xi, Keeton, Adam B, Abadi, Ashraf H, Moyer, Mary P, Grizzle, William E, Chang, Wen-Chi, Clapper, Margie L, Piazza, Gary A
Published in Molecular cancer therapeutics (01.09.2013)
Published in Molecular cancer therapeutics (01.09.2013)
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Phosphodiesterase 10A is overexpressed in lung tumor cells and inhibitors selectively suppress growth by blocking β-catenin and MAPK signaling
Zhu, Bing, Lindsey, Ashley, Li, Nan, Lee, Kevin, Ramirez-Alcantara, Veronica, Canzoneri, Joshua C, Fajardo, Alexandra, Madeira da Silva, Luciana, Thomas, Meagan, Piazza, John T, Yet, Larry, Eberhardt, Brian T, Gurpinar, Evrim, Otali, Dennis, Grizzle, William, Valiyaveettil, Jacob, Chen, Xi, Keeton, Adam B, Piazza, Gary A
Published in Oncotarget (19.09.2017)
Published in Oncotarget (19.09.2017)
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Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activity
Li, N, Lee, K, Xi, Y, Zhu, B, Gary, B D, Ramírez-Alcántara, V, Gurpinar, E, Canzoneri, J C, Fajardo, A, Sigler, S, Piazza, J T, Chen, X, Andrews, J, Thomas, M, Lu, W, Li, Y, Laan, D J, Moyer, M P, Russo, S, Eberhardt, B T, Yet, L, Keeton, A B, Grizzle, W E, Piazza, G A
Published in Oncogene (19.03.2015)
Published in Oncogene (19.03.2015)
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A novel sulindac derivative inhibits lung adenocarcinoma cell growth through suppression of Akt/mTOR signaling and induction of autophagy
Gurpinar, Evrim, Grizzle, William E, Shacka, John J, Mader, Burton J, Li, Nan, Piazza, Nicholas A, Russo, Suzanne, Keeton, Adam B, Piazza, Gary A
Published in Molecular cancer therapeutics (01.05.2013)
Published in Molecular cancer therapeutics (01.05.2013)
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Abstract 587: A novel non-COX-inhibitory sulindac derivative induces autophagic cell death by inhibiting Akt signaling in lung cancer cells
Gurpinar, Evrim, Grizzle, William E., Shacka, John J., Li, Nan, Keeton, Adam B., Piazza, Gary A.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Abstract 950: Antitumor activity of a novel phosphodiesterase 10 inhibitor in an orthotopic mouse model of lung cancer
Ramirez-Alcantara, Veronica, Schuler, Michele, Zhu, Bing, Li, Nan, Gurpinar, Evrim, Otali, Dennis, Canzoneri, Joshua, Keeton, Adam, Gary, Bernard, Russo, Suzanne, Coward, Lori, Gorman, Gregory, Grizzle, William, Chen, Xi, Boyd, Michael, Piazza, Gary
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Abstract LB-355: A novel non-COX-inhibitory sulindac derivative induces autophagic cell death in lung adenocarcinoma cells
Gurpinar, Evrim, Grizzle, William E., Liu, Yanwen, Shacka, John J., Keeton, Adam B., Piazza, Gary A.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Abstract 1761: PDE10, a novel therapeutic target for lung cancer
Zhu, Bing, Li, Nan, Ramirez-Alcantara, Veronica, Canzoneri, Joshua, Gurpinar, Evrim, Fajardo, Alexandra, Lee, Kevin, Sigler, Sara, Gary, Bernard, Thomas, Meagan, Keeton, Adam, Chen, Xi, Grizzle, William, Piazza, Gary
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Abstract 1768: A novel PDE10 inhibitor suppresses tumor growth in an orthotopic mouse model of lung cancer
Ramirez-Alcantara, Veronica, Schuler, Michele A., Zhu, Bing, Li, Nan, Gurpinar, Evrim, Canzoneri, Joshua, Keeton, Adam, Gary, Bernard, Russo, Suzanne, Coward, Lori, Gorman, Gregory S., Grizzle, William, Chen, Xi, Piazza, Gary A.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Abstract 3659: Next generation sulindac
Li, Nan, Xi, Yaguang, Tinsley, Heather N., Gurpinar, Evrim, Gary, Bernard D., Zhu, Bing, Li, Yonghe, Keeton, Adam B., Grizzle, William E., Piazza, Gary A.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Abstract 1773: Phosphodiesterase 10A: A novel target for selective inhibition of colon tumor cell growth and Wnt/β-catenin signaling
Li, Nan, Lee, Kevin, Xi, Yaguang, Zhu, Bing, Gary, Bernary D., Ramírez-Alcántara, Verónica, Gurpinar, Evrim, Canzoneri, Joshua C., Fajardo, Alexandra, Sigler, Sara, Piazza, John T., Chen, Xi, Andrews, Joel, Lu, Wenyan, Li, Yonghe, Russo, Suzanne, Yet, Larry, Keeton, Adam B., Grizzle, William E., Piazza, Gary A.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Trisubstituted and tetrasubstituted pyrazolines as a novel class of cell-growth inhibitors in tumor cells with wild type p53
Abdel-Halim, Mohammad, Keeton, Adam B., Gurpinar, Evrim, Gary, Bernard D., Vogel, Simon M., Engel, Matthias, Piazza, Gary A., Boeckler, Frank M., Hartmann, Rolf W., Abadi, Ashraf H.
Published in Bioorganic & medicinal chemistry (01.12.2013)
Published in Bioorganic & medicinal chemistry (01.12.2013)
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Phosphodiesterase 10, a novel target in colon cancer
Russo, Suzanne, Li, Nan, Lee, Kevin, Xi, Yaguang, Zhu, Bing, Gary, Bernard, Ramirez, Veronica, Gurpinar, Evrim, Canzeroni, Joshua, Fajardo, Alexandra, Sigler, Sara, Piazza, John T., Chen, Xi, Andrews, Joel, Li, Yonghe, Eberhardt, Brian, Yet, Larry, Keeton, Adam, Grizzle, William E., Piazza, Gary
Published in Journal of clinical oncology (20.01.2014)
Published in Journal of clinical oncology (20.01.2014)
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Journal Article
Abstract C182: Phosphodiesterase 10: A novel cancer target
Li, Nan, Lee, Kevin, Xi, Yaguang, Zhu, Bing, Gary, Bernard D., Ramirez-Alcantara, Veronica, Gurpinar, Evrim, Canzoneri, Joshua, Fajardo, Alexandra, Sigler, Sara, Piazza, John T., Chen, Xi, Andrews, Joel, Thomas, Meagan, Lu, Wenyan, Li, Yonghe, Laan, Danuel J., Moyer, Mary P., Russo, Suzanne, Eberhardt, Brian T., Yet, Larry, Keeton, Adam B., Grizzle, William E., Piazza, Gary A.
Published in Molecular cancer therapeutics (01.11.2013)
Published in Molecular cancer therapeutics (01.11.2013)
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Journal Article
Abstract 4610: NO-NSAIDs inhibit colon tumor cell growth by a cGMP-independent mechanism
Gurpinar, Evrim, Sun, Yanjie, Keeton, Adam, Tinsley, Heather, Gary, Bernard, Butler, Braeden L., Binkowski, Brock F., Kopelovich, Levy, Athar, Mohammad, Piazza, Gary A.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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