Apicidin: A Novel Antiprotozoal Agent that Inhibits Parasite Histone Deacetylase
Darkin-Rattray, Sandra J., Gurnett, Anne M., Myers, Robert W., Dulski, Paula M., Crumley, Tami M., Allocco, John J., Cannova, Christine, Meinke, Peter T., Colletti, Steven L., Bednarek, Maria A., Singh, Sheo B., Goetz, Michael A., Dombrowski, Anne W., Polishook, Jon D., Schmatz, Dennis M.
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Published in Proceedings of the National Academy of Sciences - PNAS (12.11.1996)
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Purification and molecular characterization of cGMP-dependent protein kinase from Apicomplexan parasites. A novel chemotherapeutic target
Gurnett, Anne M, Liberator, Paul A, Dulski, Paula M, Salowe, Scott P, Donald, Robert G K, Anderson, Jennifer W, Wiltsie, Judyann, Diaz, Carmen A, Harris, Georgiana, Chang, Ben, Darkin-Rattray, Sandra J, Nare, Bakela, Crumley, Tami, Blum, Penny Sue, Misura, Andrew S, Tamas, Tamas, Sardana, Mohinder K, Yuan, Jeffrey, Biftu, Tesfaye, Schmatz, Dennis M
Published in The Journal of biological chemistry (03.05.2002)
Published in The Journal of biological chemistry (03.05.2002)
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Highly Substituted Terphenyls as Inhibitors of Parasite cGMP-Dependent Protein Kinase Activity
Zhang, Chaowei, Ondeyka, John G, Herath, Kithsiri B, Guan, Ziqiang, Collado, Javier, Pelaez, Fernando, Leavitt, Penny S, Gurnett, Anne, Nare, Bakela, Liberator, Paul, Singh, Sheo B
Published in Journal of natural products (Washington, D.C.) (01.04.2006)
Published in Journal of natural products (Washington, D.C.) (01.04.2006)
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A structural motif in the variant surface glycoproteins of Trypanosoma brucei
Blum, Michael L, Down, James A, Gurnett, Anne M, Carrington, Mark, Turner, Mervyn J, Wiley, Don C
Published in Nature (London) (15.04.1993)
Published in Nature (London) (15.04.1993)
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Triptolide binds covalently to a 90kDa nuclear protein. Role of epoxides in binding and activity
McCallum, Christine, Kwon, Suzy, Leavitt, Penny, Shen, Dong-Ming, Liu, Wensheng, Gurnett, Anne
Published in Immunobiology (1979) (01.09.2007)
Published in Immunobiology (1979) (01.09.2007)
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Broad spectrum antiprotozoal agents that inhibit histone deacetylase: Structure-activity relationships of apicidin. Part 1
COLLETTI, Steven L, MYERS, Robert W, CRUMLEY, Tami M, CANNOVA, Christine, SCHMATZ, Dennis M, WYVRATT, Matthew J, FISHER, Michael H, MEINKE, Peter T, DARKIN-RATTRAY, Sandra J, GURNETT, Anne M, DULSKI, Paula M, GALUSKA, Stefan, ALLOCCO, John J, AYER, Michelle B, CHUNSHI LI, LIM, Julie
Published in Bioorganic & medicinal chemistry letters (22.01.2001)
Published in Bioorganic & medicinal chemistry letters (22.01.2001)
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Synthesis of Apicidin-Derived Quinolone Derivatives: Parasite-Selective Histone Deacetylase Inhibitors and Antiproliferative Agents
Meinke, Peter T, Colletti, Steven L, Doss, George, Myers, Robert W, Gurnett, Anne M, Dulski, Paula M, Darkin-Rattray, Sandra J, Allocco, John J, Galuska, Stefan, Schmatz, Dennis M, Wyvratt, Matthew J, Fisher, Michael H
Published in Journal of medicinal chemistry (14.12.2000)
Published in Journal of medicinal chemistry (14.12.2000)
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Synthesis and biological activity of anticoccidial agents: 5,6-Diarylimidazo[2,1- b][1,3]thiazoles
Scribner, Andrew, Meitz, Susan, Fisher, Michael, Wyvratt, Matthew, Leavitt, Penny, Liberator, Paul, Gurnett, Anne, Brown, Chris, Mathew, John, Thompson, Donald, Schmatz, Dennis, Biftu, Tesfaye
Published in Bioorganic & medicinal chemistry (01.10.2008)
Published in Bioorganic & medicinal chemistry (01.10.2008)
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Selective labeling of intracellular parasite proteins by using ricin
Gurnett, A M, Dulski, P M, Darkin-Rattray, S J, Carrington, M J, Schmatz, D M
Published in Proceedings of the National Academy of Sciences - PNAS (14.03.1995)
Published in Proceedings of the National Academy of Sciences - PNAS (14.03.1995)
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Purification and Molecular Characterization of cGMP-dependent Protein Kinase from Apicomplexan Parasites
Gurnett, Anne M., Liberator, Paul A., Dulski, Paula M., Salowe, Scott P., Donald, Robert G.K., Anderson, Jennifer W., Wiltsie, Judyann, Diaz, Carmen A., Harris, Georgiana, Chang, Ben, Darkin-Rattray, Sandra J., Nare, Bakela, Crumley, Tami, Blum, Penny Sue, Misura, Andrew S., Tamas, Tamas, Sardana, Mohinder K., Yuan, Jeffrey, Biftu, Tesfaye, Schmatz, Dennis M.
Published in The Journal of biological chemistry (03.05.2002)
Published in The Journal of biological chemistry (03.05.2002)
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Synthesis and biological activity of imidazopyridine anticoccidial agents: Part II
Scribner, Andrew, Dennis, Richard, Lee, Shuliang, Ouvry, Gilles, Perrey, David, Fisher, Michael, Wyvratt, Matthew, Leavitt, Penny, Liberator, Paul, Gurnett, Anne, Brown, Chris, Mathew, John, Thompson, Donald, Schmatz, Dennis, Biftu, Tesfaye
Published in European journal of medicinal chemistry (01.06.2008)
Published in European journal of medicinal chemistry (01.06.2008)
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Synthesis and biological activity of imidazopyridine anticoccidial agents: Part I
Scribner, Andrew, Dennis, Richard, Hong, Jean, Lee, Shuliang, McIntyre, Donald, Perrey, David, Feng, Dennis, Fisher, Michael, Wyvratt, Matthew, Leavitt, Penny, Liberator, Paul, Gurnett, Anne, Brown, Chris, Mathew, John, Thompson, Donald, Schmatz, Dennis, Biftu, Tesfaye
Published in European journal of medicinal chemistry (01.11.2007)
Published in European journal of medicinal chemistry (01.11.2007)
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Triptolide binds covalently to a 90 kDa nuclear protein. Role of epoxides in binding and activity
McCallum, Christine, Kwon, Suzy, Leavitt, Penny, Shen, Dong-Ming, Liu, Wensheng, Gurnett, Anne
Published in Immunobiology (1979) (01.01.2007)
Published in Immunobiology (1979) (01.01.2007)
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Synthesis and SAR studies of very potent imidazopyridine antiprotozoal agents
Biftu, Tesfaye, Feng, Dennis, Fisher, Michael, Liang, Gui-Bai, Qian, Xiaoxia, Scribner, Andrew, Dennis, Richard, Lee, Shuliang, Liberator, Paul A., Brown, Chris, Gurnett, Anne, Leavitt, Penny S., Thompson, Donald, Mathew, John, Misura, Andrew, Samaras, Samantha, Tamas, Tamas, Sina, Joseph F., McNulty, Kathleen A., McKnight, Crystal G., Schmatz, Dennis M., Wyvratt, Matthew
Published in Bioorganic & medicinal chemistry letters (01.05.2006)
Published in Bioorganic & medicinal chemistry letters (01.05.2006)
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Synthesis and biological activity of anticoccidial agents: 2,3-diarylindoles
Scribner, Andrew, Moore, Joseph A., Ouvry, Gilles, Fisher, Michael, Wyvratt, Matthew, Leavitt, Penny, Liberator, Paul, Gurnett, Anne, Brown, Chris, Mathew, John, Thompson, Donald, Schmatz, Dennis, Biftu, Tesfaye
Published in Bioorganic & medicinal chemistry letters (01.03.2009)
Published in Bioorganic & medicinal chemistry letters (01.03.2009)
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Synthesis and SAR studies of potent imidazopyridine anticoccidial agents
Liang, Gui-Bai, Qian, Xiaoxia, Feng, Dennis, Fisher, Michael, Brown, Christine M., Gurnett, Anne, Leavitt, Penny Sue, Liberator, Paul A., Misura, Andrew S., Tamas, Tamas, Schmatz, Dennis M., Wyvratt, Matthew, Biftu, Tesfaye
Published in Bioorganic & medicinal chemistry letters (01.07.2007)
Published in Bioorganic & medicinal chemistry letters (01.07.2007)
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N-Alkyl-4-piperidinyl-2,3-diarylpyrrole derivatives with heterocyclic substitutions as potent and broad spectrum anticoccidial agents
Liang, Gui-Bai, Qian, Xiaoxia, Feng, Dennis, Fisher, Michael, Crumley, Tami, Darkin-Rattray, Sandra J., Dulski, Paula M., Gurnett, Anne, Leavitt, Penny Sue, Liberator, Paul A., Misura, Andrew S., Samaras, Samantha, Tamas, Tamas, Schmatz, Dennis M., Wyvratt, Matthew, Biftu, Tesfaye
Published in Bioorganic & medicinal chemistry (15.03.2008)
Published in Bioorganic & medicinal chemistry (15.03.2008)
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Synthesis and SAR of 2-(4-fluorophenyl)-3-pyrimidin-4-ylimidazo[1,2- a]pyridine derivatives as anticoccidial agents
Feng, Dennis, Fisher, Michael, Liang, Gui-Bai, Qian, Xiaoxia, Brown, Chris, Gurnett, Anne, Leavitt, Penny Sue, Liberator, Paul A., Mathew, John, Misura, Andrew, Samaras, Samantha, Tamas, Tamas, Schmatz, Dennis M., Wyvratt, Matthew, Biftu, Tesfaye
Published in Bioorganic & medicinal chemistry letters (01.12.2006)
Published in Bioorganic & medicinal chemistry letters (01.12.2006)
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Synthesis and SAR of 2,3-diarylpyrrole inhibitors of parasite cGMP-dependent protein kinase as novel anticoccidial agents
Biftu, Tesfaye, Feng, Dennis, Ponpipom, Mitree, Girotra, Narindar, Liang, Gui-Bai, Qian, Xiaoxia, Bugianesi, Robert, Simeone, Joseph, Chang, Linda, Gurnett, Anne, Liberator, Paul, Dulski, Paula, Leavitt, Penny Sue, Crumley, Tami, Misura, Andrew, Murphy, Terence, Rattray, Sandra, Samaras, Samantha, Tamas, Tamas, Mathew, John, Brown, Christine, Thompson, Don, Schmatz, Dennis, Fisher, Michael, Wyvratt, Matthew
Published in Bioorganic & medicinal chemistry letters (01.07.2005)
Published in Bioorganic & medicinal chemistry letters (01.07.2005)
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