Synthesis of Some Benzimidazole-derived Molecules and their Effects on PARP-1 Activity and MDA-MB-231, MDA-MB-436, MDA-MB-468 Breast Cancer Cell Viability
Gurkan-Alp, A Selen, Alp, Mehmet, Karabay, Arzu Z, Koc, Asli, Buyukbingol, Erdem
Published in Anti-cancer agents in medicinal chemistry (01.01.2020)
Published in Anti-cancer agents in medicinal chemistry (01.01.2020)
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Journal Article
Synthesis, anticancer activities and molecular modeling studies of novel indole retinoid derivatives
Gurkan-Alp, A. Selen, Mumcuoglu, Mine, Andac, Cenk A., Dayanc, Emre, Cetin-Atalay, Rengul, Buyukbingol, Erdem
Published in European journal of medicinal chemistry (01.12.2012)
Published in European journal of medicinal chemistry (01.12.2012)
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Journal Article
Apoptotic Effects of Some Tetrahydronaphthalene Derivatives on K562 Human Chronic Myelogenous Leukemia Cell Line
Koc, Asli, Ozkan, Tulin, Hekmatshoar, Yalda, Gurkan-Alp, A Selen, Aktan, Fugen, Buyukbingol, Zeliha, Sunguroglu, Asuman, Buyukbingol, Erdem, Karabay, Arzu Zeynep
Published in Anti-cancer agents in medicinal chemistry (07.02.2018)
Published in Anti-cancer agents in medicinal chemistry (07.02.2018)
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Journal Article
Compressed images for affinity prediction (CIFAP): a study on predicting binding affinities for checkpoint kinase 1 protein inhibitors
Erdas, Ozlem, Andac, Cenk A., Selen Gurkan-Alp, A., Alpaslan, Ferda Nur, Buyukbingol, Erdem
Published in Journal of chemometrics (01.06.2013)
Published in Journal of chemometrics (01.06.2013)
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Some 2‐[4‐( 1H ‐benzimidazol‐1‐yl) phenyl]‐ 1H ‐benzimidazole derivatives overcome imatinib resistance by induction of apoptosis and reduction of P‐glycoprotein activity
Hekmatshoar, Yalda, Ozkan, Tulin, Alp, Mehmet, Gurkan‐Alp, A. Selen, Sunguroglu, Asuman
Published in Chemical biology & drug design (01.12.2023)
Published in Chemical biology & drug design (01.12.2023)
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Journal Article
Synthesis and effects of some novel tetrahydronaphthalene derivatives on proliferation and nitric oxide production in lipopolysaccharide activated Raw 264.7 macrophages
Gurkan, A. Selen, Karabay, Arzu Z., Buyukbingol, Zeliha, Buyukbingol, Erdem
Published in European journal of medicinal chemistry (01.02.2011)
Published in European journal of medicinal chemistry (01.02.2011)
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Journal Article
Inhibitory effects of indole α-lipoic acid derivatives on nitric oxide production in LPS/IFNγ activated RAW 264.7 macrophages
Karabay, Arzu Zeynep, Koc, Aslı, Gurkan-Alp, A. Selen, Buyukbingol, Zeliha, Buyukbingol, Erdem
Published in Cell biochemistry and function (01.04.2015)
Published in Cell biochemistry and function (01.04.2015)
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Journal Article
Design, synthesis and docking studies of benzimidazole derivatives as potential EGFR inhibitors
Celik, İsmail, Ayhan-Kılcıgil, Gülgün, Guven, Berna, Kara, Zümra, Gurkan-Alp, A. Selen, Karayel, Arzu, Onay-Besikci, Arzu
Published in European journal of medicinal chemistry (01.07.2019)
Published in European journal of medicinal chemistry (01.07.2019)
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Nilotinib exhibits less toxicity than imatinib and influences the immune state by modulating iNOS, p-p38 and p-JNK in LPS/IFN gamma-activated macrophages
Karabay, Arzu Zeynep, Ozkan, Tulin, Koc, Asli, Hekmatshoar, Yalda, Gurkan-Alp, A Selen, Sunguroglu, Asuman
Published in Toxicology in vitro (01.03.2024)
Published in Toxicology in vitro (01.03.2024)
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Journal Article
Synthesis and Evaluation of Antioxidant Properties of Novel 2-[2-(4-chlorophenyl) benzimidazole-1-yl]-N-(2-arylmethylene amino) acetamides and 2-[2-(4-chlorophenyl) benzimidazole-1-yl]-N-(4-oxo-2-aryl-thiazolidine-3-yl) acetamides-I
Ayhan-Kilcigil, Gulgun, Gurkan, Selen, Coban, Tulay, Ozdamar, Elcin Deniz, Can-Eke, Benay
Published in Chemical biology & drug design (01.05.2012)
Published in Chemical biology & drug design (01.05.2012)
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Journal Article
Retinoid N-(1H-benzo[d]imidazol-2-yl)-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carboxamide induces p21-dependent senescence in breast cancer cells
Mumcuoglu, Mine, Gurkan-Alp, A. Selen, Buyukbingol, Erdem, Cetin-Atalay, Rengul
Published in Steroids (01.04.2016)
Published in Steroids (01.04.2016)
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Journal Article
Synthesis and antiproliferative evaluation of novel 5-(4-methylpiperazin-1-yl)-2-phenyl- 1H-benzimidazole derivatives
Alp, Mehmet, Gurkan-Alp, A. Selen, Ozkan, Tulin, Sunguroglu, Asuman
Published in Zeitschrift für Naturforschung C. A journal of biosciences (01.03.2015)
Published in Zeitschrift für Naturforschung C. A journal of biosciences (01.03.2015)
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Journal Article
Compressed images for affinity prediction-2 (CIFAP-2): an improved machine learning methodology on protein-ligand interactions based on a study on caspase 3 inhibitors
Erdas, Ozlem, Andac, Cenk. A., Gurkan-Alp, A. Selen, Alpaslan, Ferda Nur, Buyukbingol, Erdem
Published in Journal of enzyme inhibition and medicinal chemistry (03.09.2015)
Published in Journal of enzyme inhibition and medicinal chemistry (03.09.2015)
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