Tuberculosis drugs' distribution and emergence of resistance in patient's lung lesions: A mechanistic model and tool for regimen and dose optimization
Strydom, Natasha, Gupta, Sneha V, Fox, William S, Via, Laura E, Bang, Hyeeun, Lee, Myungsun, Eum, Seokyong, Shim, TaeSun, Barry, 3rd, Clifton E, Zimmerman, Matthew, Dartois, Véronique, Savic, Radojka M
Published in PLoS medicine (02.04.2019)
Published in PLoS medicine (02.04.2019)
Get full text
Journal Article
Resistance to the Translation Initiation Inhibitor Silvestrol is Mediated by ABCB1/P-Glycoprotein Overexpression in Acute Lymphoblastic Leukemia Cells
Gupta, Sneha V., Sass, Ellen J., Davis, Melanie E., Edwards, Ryan B., Lozanski, Gerard, Heerema, Nyla A., Lehman, Amy, Zhang, Xiaoli, Jarjoura, David, Byrd, John C., Pan, Li, Chan, Kenneth K., Kinghorn, A. Douglas, Phelps, Mitch A., Grever, Michael R., Lucas, David M.
Published in The AAPS journal (01.09.2011)
Published in The AAPS journal (01.09.2011)
Get full text
Journal Article
Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology
Piccoli, Luca, Park, Young-Jun, Tortorici, M. Alejandra, Czudnochowski, Nadine, Walls, Alexandra C., Beltramello, Martina, Silacci-Fregni, Chiara, Pinto, Dora, Rosen, Laura E., Bowen, John E., Acton, Oliver J., Jaconi, Stefano, Guarino, Barbara, Minola, Andrea, Zatta, Fabrizia, Sprugasci, Nicole, Bassi, Jessica, Peter, Alessia, De Marco, Anna, Nix, Jay C., Mele, Federico, Jovic, Sandra, Rodriguez, Blanca Fernandez, Gupta, Sneha V., Jin, Feng, Piumatti, Giovanni, Lo Presti, Giorgia, Pellanda, Alessandra Franzetti, Biggiogero, Maira, Tarkowski, Maciej, Pizzuto, Matteo S., Cameroni, Elisabetta, Havenar-Daughton, Colin, Smithey, Megan, Hong, David, Lepori, Valentino, Albanese, Emiliano, Ceschi, Alessandro, Bernasconi, Enos, Elzi, Luigia, Ferrari, Paolo, Garzoni, Christian, Riva, Agostino, Snell, Gyorgy, Sallusto, Federica, Fink, Katja, Virgin, Herbert W., Lanzavecchia, Antonio, Corti, Davide, Veesler, David
Published in Cell (12.11.2020)
Published in Cell (12.11.2020)
Get full text
Journal Article
Web Resource
Clinical and Preclinical Single-Dose Pharmacokinetics of VIR-2218, an RNAi Therapeutic Targeting HBV Infection
Gupta, Sneha V., Fanget, Marie C., MacLauchlin, Christopher, Clausen, Valerie A., Li, Jing, Cloutier, Daniel, Shen, Ling, Robbie, Gabriel J., Mogalian, Erik
Published in Drugs in R&D (01.12.2021)
Published in Drugs in R&D (01.12.2021)
Get full text
Journal Article
ER stress and autophagy: new discoveries in the mechanism of action and drug resistance of the cyclin-dependent kinase inhibitor flavopiridol
Mahoney, Emilia, Lucas, David M., Gupta, Sneha V., Wagner, Amy J., Herman, Sarah E.M., Smith, Lisa L., Yeh, Yuh-Ying, Andritsos, Leslie, Jones, Jeffrey A., Flynn, Joseph M., Blum, Kristie A., Zhang, Xiaoli, Lehman, Amy, Kong, Hui, Gurcan, Metin, Grever, Michael R., Johnson, Amy J., Byrd, John C.
Published in Blood (09.08.2012)
Published in Blood (09.08.2012)
Get full text
Journal Article
The Proteasome Inhibitor Carfilzomib Functions Independently of p53 to Induce Cytotoxicity and an Atypical NF-κB Response in Chronic Lymphocytic Leukemia Cells
GUPTA, Sneha V, HERTLEIN, Erin, BYRD, John C, LUCAS, David M, YANHUI LU, SASS, Ellen J, LAPALOMBELLA, Rosa, CHEN, Timothy L, DAVIS, Melanie E, WOYACH, Jennifer A, LEHMAN, Amy, JARJOURA, David
Published in Clinical cancer research (01.05.2013)
Published in Clinical cancer research (01.05.2013)
Get full text
Journal Article
Potentiating Effect of the Flavonolignan (-)-Hydnocarpin in Combination with Vincristine in a Sensitive and P-gp-Expressing Acute Lymphoblastic Leukemia Cell Line
Bueno Pérez, Lynette, Pan, Li, Sass, Ellen, Gupta, Sneha V., Lehman, Amy, Kinghorn, A. Douglas, Lucas, David M.
Published in Phytotherapy research (01.11.2013)
Published in Phytotherapy research (01.11.2013)
Get full text
Journal Article
Characterization of Silvestrol Pharmacokinetics in Mice Using Liquid Chromatography–Tandem Mass Spectrometry
Saradhi, U. V. R. Vijaya, Gupta, Sneha V., Chiu, Ming, Wang, Jiang, Ling, Yonghua, Liu, Zhongfa, Newman, David J., Covey, Joseph M., Kinghorn, A. Douglas, Marcucci, Guido, Lucas, David M., Grever, Michael R., Phelps, Mitch A., Chan, Kenneth K.
Published in The AAPS journal (01.09.2011)
Published in The AAPS journal (01.09.2011)
Get full text
Journal Article
Single dose pharmacokinetics of VIR-3434, a novel neutralizing monoclonal antibody, in participants with chronic hepatitis B virus infection
Gupta, Sneha V., Elie, Sophia, Arizpe, Andre, Hristopoulos, George, Wu, Pan, Cloutier, Daniel, Reyes, Maribel
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
Get full text
Journal Article
SAT-177 - Single dose pharmacokinetics of VIR-3434, a novel neutralizing monoclonal antibody, in participants with chronic hepatitis B virus infection
Gupta, Sneha V., Elie, Sophia, Arizpe, Andre, Hristopoulos, George, Wu, Pan, Cloutier, Daniel, Reyes, Maribel
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
Get full text
Journal Article
Longer treatment duration of monthly VIR-2218 results in deeper and more sustained reductions in hepatitis B surface antigen in participants with chronic hepatitis B infection
Lim, Young-Suk, Yuen, Man-Fung, Cloutier, Daniel, Thanawala, Vaidehi, Shen, Ling, Gupta, Sneha V., Arizpe, Andre, Cathcart, Andrea, Hwang, Carey, Gane, Edward J.
Published in Journal of hepatology (01.07.2022)
Published in Journal of hepatology (01.07.2022)
Get full text
Journal Article
Safety and antiviral activity of short-duration combinations of the investigational small interfering ribonucleic acid VIR-2218 with the neutralizing, vaccinal monoclonal antibody VIR-3434: post-treatment follow-up from the Phase 2 MARCH trial
Gane, Edward J., Jucov, Alina, Dobryanksa, Marta, yoon, Ki Tae, Lim, Tien Huey, Arizpe, Andre, Cloutier, Daniel, Chattergoon, Michael, Mao, Shenghua, Gupta, Sneha V., Camus, Gregory, Hwang, Carey, Lim, Young-Suk
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
Get full text
Journal Article
Safety and efficacy of VIR-2218 with or without pegylated interferon alfa in virally-suppressed participants with chronic hepatitis B virus infection: post-treatment follow-up
Yuen, Man-Fung, Lim, Young-Suk, yoon, Ki Tae, Lim, Tien Huey, Heo, Jeong, Tangkijvanich, Pisit, Tak, Won Young, Thanawala, Vaidehi, Cloutier, Daniel, Mao, Shenghua, Arizpe, Andre, Cathcart, Andrea, Gupta, Sneha V., Hwang, Carey, Gane, Edward J.
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
Get full text
Journal Article
OS-031 - Safety and antiviral activity of short-duration combinations of the investigational small interfering ribonucleic acid VIR-2218 with the neutralizing, vaccinal monoclonal antibody VIR-3434: post-treatment follow-up from the Phase 2 MARCH trial
Gane, Edward J., Jucov, Alina, Dobryanksa, Marta, yoon, Ki Tae, Lim, Tien Huey, Arizpe, Andre, Cloutier, Daniel, Chattergoon, Michael, Mao, Shenghua, Gupta, Sneha V., Camus, Gregory, Hwang, Carey, Lim, Young-Suk
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
Get full text
Journal Article
LBO-02 - Safety and efficacy of VIR-2218 with or without pegylated interferon alfa in virally-suppressed participants with chronic hepatitis B virus infection: post-treatment follow-up
Yuen, Man-Fung, Lim, Young-Suk, yoon, Ki Tae, Lim, Tien Huey, Heo, Jeong, Tangkijvanich, Pisit, Tak, Won Young, Thanawala, Vaidehi, Cloutier, Daniel, Mao, Shenghua, Arizpe, Andre, Cathcart, Andrea, Gupta, Sneha V., Hwang, Carey, Gane, Edward J.
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
Get full text
Journal Article
Dose-dependent durability of hepatitis B surface antigen reductions following administration of a single dose of VIR-3434, a novel neutralizing vaccinal monoclonal antibody
Agarwal, Kosh, Yuen, Man-Fung, Wedemeyer, Heiner, Cloutier, Daniel, Shen, Ling, Arizpe, Andre, Gupta, Sneha V., Fanget, Marie C., Seu, Lillian, Cathcart, Andrea, Lau, Audrey H., Hwang, Carey, Gane, Edward J
Published in Journal of hepatology (01.07.2022)
Published in Journal of hepatology (01.07.2022)
Get full text
Journal Article
The Novel Proteasome Inhibitor Carfilzomib Functions Independently of p53 to Induce Potent Cytotoxicity in Primary Chronic Lymphocytic Leukemia Cells and a Defective NF-κB Response
Gupta, Sneha V., Hertlein, Erin K, Woyach, Jennifer A., Sass, Ellen J., Davis, Melanie E., Byrd, John C., Lucas, David M.
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
Get full text
Journal Article