GDC-0449—A potent inhibitor of the hedgehog pathway
Robarge, Kirk D., Brunton, Shirley A., Castanedo, Georgette M., Cui, Yong, Dina, Michael S., Goldsmith, Richard, Gould, Stephen E., Guichert, Oivin, Gunzner, Janet L., Halladay, Jason, Jia, Wei, Khojasteh, Cyrus, Koehler, Michael F.T., Kotkow, Karen, La, Hank, LaLonde, Rebecca L., Lau, Kevin, Lee, Leslie, Marshall, Derek, Marsters, James C., Murray, Lesley J., Qian, Changgeng, Rubin, Lee L., Salphati, Laurent, Stanley, Mark S., Stibbard, John H.A., Sutherlin, Daniel P., Ubhayaker, Savita, Wang, Shumei, Wong, Susan, Xie, Minli
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
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Callipeltoside A: Assignment of Absolute and Relative Configuration by Total Synthesis
Trost, Barry M., Dirat, Olivier, Gunzner, Janet L.
Published in Angewandte Chemie (International ed.) (01.03.2002)
Published in Angewandte Chemie (International ed.) (01.03.2002)
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Total synthesis of brevetoxin A
Nicolaou, K. C, Yang, Zhen, Shi, Guo-qiang, Gunzner, Janet L, Agrios, Konstantinos A, Gärtner, Peter
Published in Nature (London) (19.03.1998)
Published in Nature (London) (19.03.1998)
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Total Synthesis of Brevetoxin A: Part 4: Final Stages and Completion
Nicolaou, K. C., Gunzner, Janet L., Shi, Guo-qiang, Agrios, Konstantinos A., Gärtner, Peter, Yang, Zhen
Published in Chemistry : a European journal (01.02.1999)
Published in Chemistry : a European journal (01.02.1999)
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Total Synthesis of Brevetoxin A: Part 1: First Generation Strategy and Construction of BCD Ring System
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Published in Chemistry : a European journal (01.02.1999)
Published in Chemistry : a European journal (01.02.1999)
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Total Synthesis of Brevetoxin A: Part 2: Second Generation Strategy and Construction of EFGH Model System
Nicolaou, K. C., Wallace, Paul A., Shi, Shuhao, Ouellette, Michael A., Bunnage, Mark E., Gunzner, Janet L., Agrios, Konstantinos A., Shi, Guo-qiang, Gärtner, Peter, Yang, Zhen
Published in Chemistry : a European journal (01.02.1999)
Published in Chemistry : a European journal (01.02.1999)
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PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF
POLSON ANDREW, FLYGARE JOHN A, RAAB HELGA E, GUNZNER JANET L, HOWARD PHILIP WILSON, MASTERSON LUKE, TIBERGHIEN ARNAUD, SPENCER SUSAN D, POLAKIS PAUL
Year of Publication 24.04.2013
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Year of Publication 24.04.2013
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AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS
ESTRADA ANTHONY, SWEENEY ZACHARY KEVIN, WANG SHUMEI, CHAN BRYAN K, BURDICK DANIEL JON, GUNZNER JANET L, ZHAO GUILING, SHORE DANIEL, CHEN HUIFEN, CHAMBERS MARK, BAKER GLENN CHARLES
Year of Publication 24.04.2013
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Year of Publication 24.04.2013
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PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING
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Year of Publication 17.12.2010
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Year of Publication 17.12.2010
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Corrigendum to “GDC-0449—A potent inhibitor of the hedgehog pathway” [Bioorg. Med. Chem. Lett. 19 (2009) 5576]
Robarge, Kirk D., Brunton, Shirley A., Castanedo, Georgette M., Cui, Yong, Dina, Michael S., Goldsmith, Richard, Gould, Stephen E., Guichert, Oivin, Gunzner, Janet L., Halladay, Jason, Jia, Wei, Khojasteh, Cyrus, Koehler, Michael F.T., Kotkow, Karen, La, Hank, LaLonde, Rebecca L., Lau, Kevin, Lee, Leslie, Marshall, Derek, Marsters, James C., Murray, Lesley J., Qian, Changgeng, Rubin, Lee L., Salphati, Laurent, Stanley, Mark S., Stibbard, John H.A., Sutherlin, Daniel P., Ubhayaker, Savita, Wang, Shumei, Wong, Susan, Xie, Minli
Published in Bioorganic & medicinal chemistry letters (2010)
Published in Bioorganic & medicinal chemistry letters (2010)
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Callipeltoside A: Assignment of Absolute and Relative Configuration by Total Synthesis We thank the National Science Foundation and the National Institutes of Health for their generous support of our programs. OD was supported in part by a fellowship from the Association pour la Recherche contre le Cancer (ARC). J.L.G. was supported in part by a NIH postdoctoral fellowship from the National Cancer Institute. Mass spectra were provided by the Mass Spectroscopy Facility at the University of Califo
Trost, Barry M., Dirat, Olivier, Gunzner, Janet L.
Published in Angewandte Chemie International Edition (01.03.2002)
Published in Angewandte Chemie International Edition (01.03.2002)
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Journal Article
Total synthesis of brevetoxin A: Part 2: Second generation strategy and construction of EFGH model system
Nicolaou, KC, Wallace, PA, Shi, SH, Ouellette, MA, Bunnage, ME, Gunzner, JL, Agrios, KA, Shi, GQ, Gartner, P, Yang, Z
Published in Chemistry : a European journal (01.02.1999)
Published in Chemistry : a European journal (01.02.1999)
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Total Synthesis of Brevetoxin A: Part 3: Construction of GHIJ and BCDE Ring Systems
Nicolaou, K. C., Shi, Guo-qiang, Gunzner, Janet L., Gärtner, Peter, Wallace, Paul A., Ouellette, Michael A., Shi, Shuhao, Bunnage, Mark E., Agrios, Konstantinos A., Veale, Chris A., Hwang, Chan-Kou, Hutchinson, John, Prasad, C. V. C., Ogilvie, William W., Yang, Zhen
Published in Chemistry : a European journal (01.02.1999)
Published in Chemistry : a European journal (01.02.1999)
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PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF
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Year of Publication 22.09.2022
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AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS
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Year of Publication 09.07.2019
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Year of Publication 09.07.2019
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AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS
CHEN, Huifen, GUNZNER, Janet L, SWEENEY, Zachary Kevin, CHAN, Bryan K, ESTRADA, Anthony, BAKER-GLENN, Charles, WANG, Shumei, SHORE, Daniel, BURDICK, Daniel Jon, CHAMBERS, Mark, ZHAO, Guiling
Year of Publication 24.10.2018
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Year of Publication 24.10.2018
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