Administration of broadly neutralizing anti-HIV-1 antibodies at ART initiation maintains long-term CD8 + T cell immunity
Rosás-Umbert, Miriam, Gunst, Jesper D, Pahus, Marie H, Olesen, Rikke, Schleimann, Mariane, Denton, Paul W, Ramos, Victor, Ward, Adam, Kinloch, Natalie N, Copertino, Dennis C, Escribà, Tuixent, Llano, Anuska, Brumme, Zabrina L, Brad Jones, R, Mothe, Beatriz, Brander, Christian, Fox, Julie, Nussenzweig, Michel C, Fidler, Sarah, Caskey, Marina, Tolstrup, Martin, Søgaard, Ole S
Published in Nature communications (29.10.2022)
Published in Nature communications (29.10.2022)
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SARS-CoV-2 persistence is associated with antigen-specific CD8 T-cell responses
Vibholm, Line K., Nielsen, Stine S.F., Pahus, Marie H., Frattari, Giacomo S., Olesen, Rikke, Andersen, Rebecca, Monrad, Ida, Andersen, Anna H.F., Thomsen, Michelle M., Konrad, Christina V., Andersen, Sidsel D., Højen, Jesper F., Gunst, Jesper D., Østergaard, Lars, Søgaard, Ole S., Schleimann, Mariane H., Tolstrup, Martin
Published in EBioMedicine (01.02.2021)
Published in EBioMedicine (01.02.2021)
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Efficacy of the TMPRSS2 inhibitor camostat mesilate in patients hospitalized with Covid-19-a double-blind randomized controlled trial
Gunst, Jesper D., Staerke, Nina B., Pahus, Marie H., Kristensen, Lena H., Bodilsen, Jacob, Lohse, Nicolai, Dalgaard, Lars S., Brønnum, Dorthe, Fröbert, Ole, Hønge, Bo, Johansen, Isik S., Monrad, Ida, Erikstrup, Christian, Rosendal, Regitze, Vilstrup, Emil, Mariager, Theis, Bove, Dorthe G., Offersen, Rasmus, Shakar, Shakil, Cajander, Sara, Jørgensen, Nis P., Sritharan, Sajitha S., Breining, Peter, Jespersen, Søren, Mortensen, Klaus L., Jensen, Mads L., Kolte, Lilian, Frattari, Giacomo S., Larsen, Carsten S., Storgaard, Merete, Nielsen, Lars P., Tolstrup, Martin, Sædder, Eva A., Østergaard, Lars J., Ngo, Hien T.T., Jensen, Morten H., Højen, Jesper F., Kjolby, Mads, Søgaard, Ole S.
Published in EClinicalMedicine (01.05.2021)
Published in EClinicalMedicine (01.05.2021)
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SARS-CoV-2 elicits robust adaptive immune responses regardless of disease severity
Nielsen, Stine SF, Vibholm, Line K, Monrad, Ida, Olesen, Rikke, Frattari, Giacomo S, Pahus, Marie H, Højen, Jesper F, Gunst, Jesper D, Erikstrup, Christian, Holleufer, Andreas, Hartmann, Rune, Østergaard, Lars, Søgaard, Ole S, Schleimann, Mariane H, Tolstrup, Martin
Published in EBioMedicine (01.06.2021)
Published in EBioMedicine (01.06.2021)
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Characteristics of a Danish Post-COVID Cohort Referred for Examination due to Persistent Symptoms Six Months after Mild Acute COVID-19
Agergaard, Jane, Ullahammer, William M, Gunst, Jesper D, Østergaard, Lars, Schiøttz-Christensen, Berit
Published in Journal of clinical medicine (10.12.2022)
Published in Journal of clinical medicine (10.12.2022)
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Journal Article
Immunomodulation with IL-7 and IL-15 in HIV-1 infection
Gunst, Jesper D., Goonetilleke, Nilu, Rasmussen, Thomas A., Søgaard, Ole S.
Published in Journal of Virus Eradication (01.09.2023)
Published in Journal of Virus Eradication (01.09.2023)
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Journal Article
Single cell analysis reveals a subset of cytotoxic-like plasmacytoid dendritic cells in people with HIV-1
Cham, Lamin B., Gunst, Jesper D., Schleimann, Mariane H., Frattari, Giacomo S., Rosas-Umbert, Miriam, Vibholm, Line K., van der Sluis, Renée M., Jakobsen, Martin R., Olesen, Rikke, Lin, Lin, Tolstrup, Martin, Søgaard, Ole S.
Published in iScience (15.09.2023)
Published in iScience (15.09.2023)
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Journal Article
Fimepinostat, a novel dual inhibitor of HDAC and PI3K, effectively reverses HIV-1 latency ex vivo without T cell activation
Gunst, Jesper D, Kjær, Kathrine, Olesen, Rikke, Rasmussen, Thomas A, Østergaard, Lars, Denton, Paul W, Søgaard, Ole S, Tolstrup, Martin
Published in Journal of Virus Eradication (18.09.2019)
Published in Journal of Virus Eradication (18.09.2019)
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Journal Article
TLR2 and TLR7 mediate distinct immunopathological and antiviral plasmacytoid dendritic cell responses to SARS‐CoV‐2 infection
Sluis, Renée M, Cham, Lamin B, Gris‐Oliver, Albert, Gammelgaard, Kristine R, Pedersen, Jesper G, Idorn, Manja, Ahmadov, Ulvi, Hernandez, Sabina Sanches, Cémalovic, Ena, Godsk, Stine H, Thyrsted, Jacob, Gunst, Jesper D, Nielsen, Silke D, Jørgensen, Janni J, Bjerg, Tobias Wang, Laustsen, Anders, Reinert, Line S, Olagnier, David, Bak, Rasmus O, Kjolby, Mads, Holm, Christian K, Tolstrup, Martin, Paludan, Søren R, Kristensen, Lasse S, Søgaard, Ole S, Jakobsen, Martin R
Published in The EMBO journal (16.05.2022)
Published in The EMBO journal (16.05.2022)
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Journal Article
Early intervention with 3BNC117 and romidepsin at antiretroviral treatment initiation in people with HIV-1: a phase 1b/2a, randomized trial
Gunst, Jesper D, Pahus, Marie H, Rosás-Umbert, Miriam, Lu, I-Na, Benfield, Thomas, Nielsen, Henrik, Johansen, Isik S, Mohey, Rajesh, Østergaard, Lars, Klastrup, Vibeke, Khan, Maryam, Schleimann, Mariane H, Olesen, Rikke, Støvring, Henrik, Denton, Paul W, Kinloch, Natalie N, Copertino, Dennis C, Ward, Adam R, Alberto, Winiffer D Conce, Nielsen, Silke D, Puertas, Maria C, Ramos, Victor, Reeves, Jacqueline D, Petropoulos, Christos J, Martinez-Picado, Javier, Brumme, Zabrina L, Jones, R Brad, Fox, Julie, Tolstrup, Martin, Nussenzweig, Michel C, Caskey, Marina, Fidler, Sarah, Søgaard, Ole S
Published in Nature medicine (01.11.2022)
Published in Nature medicine (01.11.2022)
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Journal Article
Impact of a TLR9 agonist and broadly neutralizing antibodies on HIV-1 persistence: the randomized phase 2a TITAN trial
Gunst, Jesper D, Højen, Jesper F, Pahus, Marie H, Rosás-Umbert, Miriam, Stiksrud, Birgitte, McMahon, James H, Denton, Paul W, Nielsen, Henrik, Johansen, Isik S, Benfield, Thomas, Leth, Steffen, Gerstoft, Jan, Østergaard, Lars, Schleimann, Mariane H, Olesen, Rikke, Støvring, Henrik, Vibholm, Line, Weis, Nina, Dyrhol-Riise, Anne M, Pedersen, Karen B H, Lau, Jillian S Y, Copertino, Jr, Dennis C, Linden, Noemi, Huynh, Tan T, Ramos, Victor, Jones, R Brad, Lewin, Sharon R, Tolstrup, Martin, Rasmussen, Thomas A, Nussenzweig, Michel C, Caskey, Marina, Reikvam, Dag Henrik, Søgaard, Ole S
Published in Nature medicine (01.10.2023)
Published in Nature medicine (01.10.2023)
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Determination of camostat and its metabolites in human plasma – Preservation of samples and quantification by a validated UHPLC-MS/MS method
Sørensen, Lambert K., Hasselstrøm, Jørgen B., Gunst, Jesper D., Søgaard, Ole S., Kjolby, Mads
Published in Clinical biochemistry (01.10.2021)
Published in Clinical biochemistry (01.10.2021)
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Journal Article
Redirector of Vaccine-induced Effector Responses (RoVER) for specific killing of cellular targets
Konrad, Christina V., Iversen, Emma F., Gunst, Jesper D., Monrad, Ida, Holleufer, Andreas, Hartmann, Rune, Østergaard, Lars J., Søgaard, Ole S., Schleimann, Mariane H., Tolstrup, Martin
Published in EBioMedicine (01.10.2023)
Published in EBioMedicine (01.10.2023)
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Journal Article
Effect of 3BNC117 and romidepsin on the HIV-1 reservoir in people taking suppressive antiretroviral therapy (ROADMAP): a randomised, open-label, phase 2A trial
Gruell, Henning, Gunst, Jesper D, Cohen, Yehuda Z, Pahus, Marie H, Malin, Jakob J, Platten, Martin, Millard, Katrina G, Tolstrup, Martin, Jones, R Brad, Conce Alberto, Winnifer D, Lorenzi, Julio C C, Oliveira, Thiago Y, Kümmerle, Tim, Suárez, Isabelle, Unson-O'Brien, Cecilia, Nogueira, Lilian, Olesen, Rikke, Østergaard, Lars, Nielsen, Henrik, Lehmann, Clara, Nussenzweig, Michel C, Fätkenheuer, Gerd, Klein, Florian, Caskey, Marina, Søgaard, Ole S
Published in The Lancet. Microbe (01.03.2022)
Published in The Lancet. Microbe (01.03.2022)
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Interleukin-37 Expression Is Increased in Chronic HIV-1-Infected Individuals and Is Associated with Inflammation and the Size of the Total Viral Reservoir
Højen, Jesper F, Rasmussen, Thomas A, Andersen, Karen Lise D, Winckelmann, Anni A, Laursen, Rune R, Gunst, Jesper D, Møller, Holger J, Fujita, Mayumi, Østergaard, Lars, Søgaard, Ole S, Dinarello, Charles A, Tolstrup, Martin
Published in Molecular medicine (Cambridge, Mass.) (14.04.2015)
Published in Molecular medicine (Cambridge, Mass.) (14.04.2015)
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Redirector of Vaccine-induced Effector Responses (RoVER) for specific killing of cellular targetsResearch in context
Christina V. Konrad, Emma F. Iversen, Jesper D. Gunst, Ida Monrad, Andreas Holleufer, Rune Hartmann, Lars J. Østergaard, Ole S. Søgaard, Mariane H. Schleimann, Martin Tolstrup
Published in EBioMedicine (01.10.2023)
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Published in EBioMedicine (01.10.2023)
Journal Article
Modest de novo Reactivation of Single HIV-1 Proviruses in Peripheral CD4+ T Cells by Romidepsin
Kjær, Kathrine, Leth, Steffen, Konrad, Christina V., Gunst, Jesper D., Nymann, Rasmus, Østergaard, Lars, Søgaard, Ole S., Schleimann, Mariane H., Tolstrup, Martin, Denton, Paul W.
Published in Frontiers in virology (online) (01.10.2021)
Published in Frontiers in virology (online) (01.10.2021)
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Journal Article
Fimepinostat, a novel dual inhibitor of HDAC and PI3K, effectively reverses HIV-1 latency ex vivo without T cell activation
Gunst, Jesper D, Kjær, Kathrine, Olesen, Rikke, Rasmussen, Thomas A, Østergaard, Lars, Denton, Paul W, Søgaard, Ole S, Tolstrup, Martin
Published in Journal of virus eradication (18.09.2019)
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Published in Journal of virus eradication (18.09.2019)
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