A phase IB study of ABT-751 in combination with docetaxel in patients with advanced castration-resistant prostate cancer
Michels, J., Ellard, S.L., Le, L., Kollmannsberger, C., Murray, N., Tomlinson Guns, E.S., Carr, R., Chi, K.N.
Published in Annals of oncology (01.02.2010)
Published in Annals of oncology (01.02.2010)
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Oral simvastatin administration delays castration-resistant progression and reduces intratumoral steroidogenesis of LNCaP prostate cancer xenografts
Gordon, J A, Midha, A, Szeitz, A, Ghaffari, M, Adomat, H H, Guo, Y, Klassen, T L, Guns, E S, Wasan, K M, Cox, M E
Published in Prostate cancer and prostatic diseases (01.03.2016)
Published in Prostate cancer and prostatic diseases (01.03.2016)
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Journal Article
Discovery and characterization of OC144-093, a novel inhibitor of P-glycoprotein-mediated multidrug resistance
NEWMAN, M. J, RODARTE, J. C, MAYER, L. D, BENBATOUL, K. D, ROMANO, S. J, CHENGZHI ZHANG, KRANE, S, MORAN, E. J, UYEDA, R. T, DIXON, R, GUNS, E. S
Published in Cancer research (Chicago, Ill.) (01.06.2000)
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Published in Cancer research (Chicago, Ill.) (01.06.2000)
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Targeting the Binding Function 3 (BF3) Site of the Human Androgen Receptor through Virtual Screening
Lack, Nathan A, Axerio-Cilies, Peter, Tavassoli, Peyman, Han, Frank Q, Chan, Ka Hong, Feau, Clementine, LeBlanc, Eric, Guns, Emma Tomlinson, Guy, R. Kiplin, Rennie, Paul S, Cherkasov, Artem
Published in Journal of medicinal chemistry (22.12.2011)
Published in Journal of medicinal chemistry (22.12.2011)
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Journal Article
Tumor-specific and Photodependent Cytotoxicity of Hypericin in the Human LNCaP Prostate Tumor Model
Xie, Xiaowei, Hudson, James B., Guns, Emma S.
Published in Photochemistry and photobiology (01.08.2001)
Published in Photochemistry and photobiology (01.08.2001)
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Journal Article
Assessment of the involvement of CYP3A in the vitro metabolism of a new modulator of MDR in cancer chemotherapy, OC144-193, by human liver microsomes
GUNS, Emma S, BULLOCK, Peter L, REIMER, Mark L. J, DIXON, Ross, BALLY, Marcel, MAYER, Lawrence D
Published in European journal of drug metabolism and pharmacokinetics (01.10.2001)
Published in European journal of drug metabolism and pharmacokinetics (01.10.2001)
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Abstracts
Bie, L., Ju, Y., Jin, Z., Donovan, L., Birks, S., Grunewald, L., Zmuda, F., Pilkington, G., Kaul, A., Chen, Y.-H., Dahiya, S., Emnett, R., Gianino, S., Gutmann, D., Poschl, J., Bianchi, E., Bockstaller, M., Neumann, P., Schuller, U., Gevorgian, A., Morozova, E., Kazantsev, I., Iukhta, T., Safonova, S., Punanov, Y., Zheludkova, O., Afanasyev, B., Buss, M., Remke, M., Gandhi, K., Kool, M., Northcott, P., Pfister, S., Taylor, M., Castellino, R., Thompson, J., Margraf, L., Donahue, D., Head, H., Murray, J., Burger, P., Wortham, M., Reitman, Z., He, Y., Bigner, D., Yan, H., Lee, C., Triscott, J., Foster, C., Manoranjan, B., Pambid, M. R., Fotovati, A., Berns, R., Venugopal, C., O'Halloran, K., Narendran, A., Taylor, M. D., Singh, S. K., Singhal, A., Rassekh, R., Maxwell, C. A., Dunham, C., Dunn, S. E., Hu, K., Adomat, H., Moniri, M., Chin, M. Y., Hessein, M., Zisman, N., Maurer, N., Guns, E., Dunn, S., Koks, C., De Vleeschouwer, S., Graf, N., Van Gool, S., D'Asti, E., Huang, A., Korshunov, A., Rak, J., Gump, W., Moriarty, T., Skjei, K., Karkare, S., Castelo-Branco, P., Choufani, S., Mack, S., Gallagher, D., Zhang, C., Merino, D., Wasserman, J., Jones, D. T., Croul, S., Hawkins, C., Hitzler, J., Wang, J. C. Y., Baruchel, S., Dirks, P. B., Malkin, D., Weksberg, R.
Published in Neuro-oncology (Charlottesville, Va.) (01.04.2013)
Published in Neuro-oncology (Charlottesville, Va.) (01.04.2013)
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A phase I study of a second generation antisense oligonucleotide to clusterin (OGX-011) in combination with docetaxel: NCIC CTG IND.154
Chi, K. N., Eisenhauer, E., Siu, L., Hirte, H., Hotte, S. J., Chia, S., Knox, J., Guns, E., Powers, J., Gleave, M. E.
Published in Journal of clinical oncology (01.06.2005)
Published in Journal of clinical oncology (01.06.2005)
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Journal Article
Rh2 synergistically enhances paclitaxel or mitoxantrone in prostate cancer models
Xie, Xiaowei, Eberding, Andy, Madera, Candice, Fazli, Ladan, Jia, William, Goldenberg, Larry, Gleave, Martin, Guns, Emma S
Published in The Journal of urology (01.05.2006)
Published in The Journal of urology (01.05.2006)
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Journal Article
Bioactive compounds from Rhodiola rosea (Crassulaceae)
Ming, D.S, Hillhouse, B.J, Guns, E.S, Eberding, A, Xie, S, Vimalanathan, S, Towers, G.H.N
Published in Phytotherapy research (01.09.2005)
Published in Phytotherapy research (01.09.2005)
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Journal Article
P-glycoprotein increases the efflux of the androgen dihydrotestosterone and reduces androgen responsive gene activity in prostate tumor cells
Fedoruk, Matthew N., Giménez-Bonafé, Pepita, Guns, Emma S., Mayer, Lawrence D., Nelson, Colleen C.
Published in The Prostate (01.04.2004)
Published in The Prostate (01.04.2004)
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Journal Article
pH modulation using CsCl enhances therapeutic effects of vitamin D in LNCaP tumor bearing mice
Guns, Emma S., Xie, Xiaowei, Fedoruk, Matthew, Madera, Candice, Cowell, Simon, Mayer, Lawrence D., Skov, Kirsten, Gleave, Martin E., Kozlowski, Piotr
Published in The Prostate (01.08.2005)
Published in The Prostate (01.08.2005)
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Journal Article
Drug interaction studies between paclitaxel (Taxol) and OC144-093: A new modulator of MDR in cancer chemotherapy
GUNS, Emma S, DENYSSEVYCH, Tetyana, DIXON, Ross, BALLY, Marcel B, MAYER, Lawrence
Published in European journal of drug metabolism and pharmacokinetics (01.04.2002)
Published in European journal of drug metabolism and pharmacokinetics (01.04.2002)
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Reduction of Cholesterol Absorption by Dietary Plant Sterols and Stanols in Mice Is Independent of the Abcg5/8 Transporter
Plösch, Torsten, Kruit, Janine K, Bloks, Vincent W, Huijkman, Nicolette C.A, Havinga, Rick, Duchateau, Guus S.M.J.E, Lin, Yuguang, Kuipers, Folkert
Published in The Journal of nutrition (01.08.2006)
Published in The Journal of nutrition (01.08.2006)
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