2-Propyl 3,3-dibromo-2-hydroxypyrrolidine-1-carboxylate
Nichol, Gary S., Gunawan, Steven, Xu, Zhigang, Dietrich, Justin, Hulme, Christopher
Published in Acta crystallographica. Section E, Structure reports online (01.03.2010)
Published in Acta crystallographica. Section E, Structure reports online (01.03.2010)
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Bifunctional building blocks in the Ugi-azide condensation reaction: a general strategy toward exploration of new molecular diversityElectronic supplementary information (ESI) available: General procedure, 1H and 13C NMR spectra for aldo/keto-esters (8b, 19b, 19 and 30). 1H and 13C NMR spectra for all new synthesized compounds (10, 10b-j, 20a-e, 22a-f, 24a-e, 29a-e and 31a-f). CCDC 936637. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c3ob40900g
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Structural Insights into JAK2 Inhibition by Ruxolitinib, Fedratinib, and Derivatives Thereof
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Published in Journal of medicinal chemistry (25.02.2021)
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Spontaneous intracerebral hemorrhage after anticoagulation therapy in a 57-year-old man with SARS-COV-2 infection: A case report
Fakhrurrazy, Fakhrurrazy, Pambudi, Pagan, Khatimah, Husnul, Runtuwene, Lily, Gunawan, Steven, Wibowo, Among, Dafif, Muhammad
Published in Journal of the neurological sciences (01.10.2021)
Published in Journal of the neurological sciences (01.10.2021)
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Concise One-Pot Preparation of Unique Bis-Pyrrolidinone Tetrazoles
Gunawan, Steven, Petit, Joachim, Hulme, Christopher
Published in ACS combinatorial science (12.03.2012)
Published in ACS combinatorial science (12.03.2012)
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Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors
Karim, Rezaul Md, Bikowitz, Melissa J, Chan, Alice, Zhu, Jin-Yi, Grassie, Dylan, Becker, Andreas, Berndt, Norbert, Gunawan, Steven, Lawrence, Nicholas J, Schönbrunn, Ernst
Published in Journal of medicinal chemistry (11.11.2021)
Published in Journal of medicinal chemistry (11.11.2021)
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Abstract 4879: Mutation selectivity of the allosteric SHP2 inhibitor SHP099
Sun, Xiaojun, Ren, Yuan, Gunawan, Steven, Teng, Peng, Chen, Zhengming, Lawrence, Harshani R., Cai, Jianfeng, Lawrence, Nicholas J., Wu, Jie
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Potent Dual BET Bromodomain-Kinase Inhibitors as Value-Added Multitargeted Chemical Probes and Cancer Therapeutics
Ember, Stuart W, Lambert, Que T, Berndt, Norbert, Gunawan, Steven, Ayaz, Muhammad, Tauro, Marilena, Zhu, Jin-Yi, Cranfill, Paula J, Greninger, Patricia, Lynch, Conor C, Benes, Cyril H, Lawrence, Harshani R, Reuther, Gary W, Lawrence, Nicholas J, Schönbrunn, Ernst
Published in Molecular cancer therapeutics (01.06.2017)
Published in Molecular cancer therapeutics (01.06.2017)
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Targeting the BRD4-HOXB13 Coregulated Transcriptional Networks with Bromodomain-Kinase Inhibitors to Suppress Metastatic Castration-Resistant Prostate Cancer
Nerlakanti, Niveditha, Yao, Jiqiang, Nguyen, Duy T, Patel, Ami K, Eroshkin, Alexey M, Lawrence, Harshani R, Ayaz, Muhammad, Kuenzi, Brent M, Agarwal, Neha, Chen, Yunyun, Gunawan, Steven, Karim, Rezaul M, Berndt, Norbert, Puskas, John, Magliocco, Anthony M, Coppola, Domenico, Dhillon, Jasreman, Zhang, Jingsong, Shymalagovindarajan, Subramaniam, Rix, Uwe, Kim, Youngchul, Perera, Ranjan, Lawrence, Nicholas J, Schonbrunn, Ernst, Mahajan, Kiran
Published in Molecular cancer therapeutics (01.12.2018)
Published in Molecular cancer therapeutics (01.12.2018)
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Synthesis of tetrazolo-fused benzodiazepines and benzodiazepinones by a two-step protocol using an Ugi-azide reaction for initial diversity generation
Gunawan, Steven, Ayaz, Muhammad, De Moliner, Fabio, Frett, Brendan, Kaiser, Christine, Patrick, Nina, Xu, Zhigang, Hulme, Christopher
Published in Tetrahedron (08.07.2012)
Published in Tetrahedron (08.07.2012)
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Targeting Aurora kinase A and JAK2 prevents GVHD while maintaining Treg and antitumor CTL function
Betts, Brian C, Veerapathran, Anandharaman, Pidala, Joseph, Yang, Hua, Horna, Pedro, Walton, Kelly, Cubitt, Christopher L, Gunawan, Steven, Lawrence, Harshani R, Lawrence, Nicholas J, Sebti, Said M, Anasetti, Claudio
Published in Science translational medicine (11.01.2017)
Published in Science translational medicine (11.01.2017)
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