Single-cell profiling guided combinatorial immunotherapy for fast-evolving CDK4/6 inhibitor-resistant HER2-positive breast cancer
Wang, Qingfei, Guldner, Ian H., Golomb, Samantha M., Sun, Longhua, Harris, Jack A., Lu, Xin, Zhang, Siyuan
Published in Nature communications (23.08.2019)
Published in Nature communications (23.08.2019)
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Journal Article
Multi-modal Single-Cell Analysis Reveals Brain Immune Landscape Plasticity during Aging and Gut Microbiota Dysbiosis
Golomb, Samantha M., Guldner, Ian H., Zhao, Anqi, Wang, Qingfei, Palakurthi, Bhavana, Aleksandrovic, Emilija A., Lopez, Jacqueline A., Lee, Shaun W., Yang, Kai, Zhang, Siyuan
Published in Cell reports (Cambridge) (01.12.2020)
Published in Cell reports (Cambridge) (01.12.2020)
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Journal Article
Targeting CXCL16 and STAT1 augments immune checkpoint blockade therapy in triple-negative breast cancer
Palakurthi, Bhavana, Fross, Shaneann R., Guldner, Ian H., Aleksandrovic, Emilija, Liu, Xiyu, Martino, Anna K., Wang, Qingfei, Neff, Ryan A., Golomb, Samantha M., Lewis, Cheryl, Peng, Yan, Howe, Erin N., Zhang, Siyuan
Published in Nature communications (13.04.2023)
Published in Nature communications (13.04.2023)
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Journal Article
Rab11b-mediated integrin recycling promotes brain metastatic adaptation and outgrowth
Howe, Erin N., Burnette, Miranda D., Justice, Melanie E., Schnepp, Patricia M., Hedrick, Victoria, Clancy, James W., Guldner, Ian H., Lamere, Alicia T., Li, Jun, Aryal, Uma K., D’Souza-Schorey, Crislyn, Zartman, Jeremiah J., Zhang, Siyuan
Published in Nature communications (15.06.2020)
Published in Nature communications (15.06.2020)
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Journal Article
GAD1 Upregulation Programs Aggressive Features of Cancer Cell Metabolism in the Brain Metastatic Microenvironment
Schnepp, Patricia M, Lee, Dennis D, Guldner, Ian H, O'Tighearnaigh, Treasa K, Howe, Erin N, Palakurthi, Bhavana, Eckert, Kaitlyn E, Toni, Tiffany A, Ashfeld, Brandon L, Zhang, Siyuan
Published in Cancer research (Chicago, Ill.) (01.06.2017)
Published in Cancer research (Chicago, Ill.) (01.06.2017)
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Journal Article
Death effector domain-containing protein induces vulnerability to cell cycle inhibition in triple-negative breast cancer
Ni, Yingjia, Schmidt, Keon R., Werner, Barnes A., Koenig, Jenna K., Guldner, Ian H., Schnepp, Patricia M., Tan, Xuejuan, Jiang, Lan, Host, Misha, Sun, Longhua, Howe, Erin N., Wu, Junmin, Littlepage, Laurie E., Nakshatri, Harikrishna, Zhang, Siyuan
Published in Nature communications (28.06.2019)
Published in Nature communications (28.06.2019)
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Journal Article
Isolation of mouse brain-infiltrating leukocytes for single cell profiling of epitopes and transcriptomes
Guldner, Ian H., Golomb, Samantha M., Wang, Qingfei, Wang, Emilia, Zhang, Siyuan
Published in STAR protocols (18.06.2021)
Published in STAR protocols (18.06.2021)
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Journal Article
CNS-Native Myeloid Cells Drive Immune Suppression in the Brain Metastatic Niche through Cxcl10
Guldner, Ian H., Wang, Qingfei, Yang, Lin, Golomb, Samantha M., Zhao, Zhuo, Lopez, Jacqueline A., Brunory, Abigail, Howe, Erin N., Zhang, Yizhe, Palakurthi, Bhavana, Barron, Martin, Gao, Hongyu, Xuei, Xiaoling, Liu, Yunlong, Li, Jun, Chen, Danny Z., Landreth, Gary E., Zhang, Siyuan
Published in Cell (25.11.2020)
Published in Cell (25.11.2020)
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Journal Article
Atlas of the aging mouse brain reveals white matter as vulnerable foci
Hahn, Oliver, Foltz, Aulden G., Atkins, Micaiah, Kedir, Blen, Moran-Losada, Patricia, Guldner, Ian H., Munson, Christy, Kern, Fabian, Pálovics, Róbert, Lu, Nannan, Zhang, Hui, Kaur, Achint, Hull, Jacob, Huguenard, John R., Grönke, Sebastian, Lehallier, Benoit, Partridge, Linda, Keller, Andreas, Wyss-Coray, Tony
Published in Cell (14.09.2023)
Published in Cell (14.09.2023)
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Journal Article
Cell surface GRP78 promotes stemness in normal and neoplastic cells
Conner, Clay, Lager, Tyson W., Guldner, Ian H., Wu, Min-Zu, Hishida, Yuriko, Hishida, Tomoaki, Ruiz, Sergio, Yamasaki, Amanda E., Gilson, Robert C., Belmonte, Juan Carlos Izpisua, Gray, Peter C., Kelber, Jonathan A., Zhang, Siyuan, Panopoulos, Athanasia D.
Published in Scientific reports (26.02.2020)
Published in Scientific reports (26.02.2020)
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Journal Article
Generating intravital super-resolution movies with conventional microscopy reveals actin dynamics that construct pioneer axons
Zhang, Yide, Nichols, Evan L, Zellmer, Abigail M, Guldner, Ian H, Kankel, Cody, Zhang, Siyuan, Howard, Scott S, Smith, Cody J
Published in Development (Cambridge) (01.03.2019)
Published in Development (Cambridge) (01.03.2019)
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Journal Article
An Integrative Platform for Three-dimensional Quantitative Analysis of Spatially Heterogeneous Metastasis Landscapes
Guldner, Ian H., Yang, Lin, Cowdrick, Kyle R., Wang, Qingfei, Alvarez Barrios, Wendy V., Zellmer, Victoria R., Zhang, Yizhe, Host, Misha, Liu, Fang, Chen, Danny Z., Zhang, Siyuan
Published in Scientific reports (12.04.2016)
Published in Scientific reports (12.04.2016)
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Journal Article
Instant FLIM enables 4D in vivo lifetime imaging of intact and injured zebrafish and mouse brains
Zhang, Yide, Guldner, Ian H., Nichols, Evan L., Benirschke, David, Smith, Cody J., Zhang, Siyuan, Howard, Scott S.
Published in Optica (20.06.2021)
Published in Optica (20.06.2021)
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Journal Article
Abstract 4841: Functional genome-wide screening identifies triple-negative breast cancer cell cycle-dependent vulnerability driven by genomic gain of death effector domain-containing protein
Ni, Yingjia, Schmidt, Keon R., Werner, Barnes A., Koenig, Jenna K., Guldner, Ian H., Schnepp, Patricia M., Tan, Xuejuan, Jiang, Lan, Host, Misha, Sun, Longhua, Howe, Erin N., Wu, Junmin, Littlepage, Laurie E., Nakshatri, Harikrishna, Zhang, Siyuan
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract 4934: Brain metastatic microenvironment reshapes cancer cell metabolism through epigenetic up-regulation of glutamate decarboxylase 1
Schnepp, Patricia M., Lee, Dennis D., Guldner, Ian H., O'Tighearnaigh, Treasa, Palakurthi, Bhavana, Eckert, Kaitlyn E., Toni, Tiffany A., Ashfeld, Brandon L., Zhang, Siyuan
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 1990: Aberrant cell surface expression of GRP78 in breast cancer cells marks a stem-like population that has increased metastatic potential in vivo
Lager, Tyson W., Conner, Henry C., Guldner, Ian H., Wu, Michael Z., Hishida, Yuriko, Hishida, Tomoaki, Ruiz, Sergio, Yamasaki, Amanda E., Belmonte, Juan Carlos Izpisua, Gray, Peter C., Kelber, Jonathan A., Zhang, Siyuan, Panopoulos, Athanasia D.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article