The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function
Foskolou, Iosifina P., Cunha, Pedro P., Sánchez-López, Elena, Minogue, Eleanor A., Nicolet, Benoît P., Guislain, Aurélie, Jorgensen, Christian, Kostidis, Sarantos, Zandhuis, Nordin D., Barbieri, Laura, Bargiela, David, Nathanael, Demitris, Tyrakis, Petros A., Palazon, Asis, Giera, Martin, Wolkers, Monika C., Johnson, Randall S.
Published in Cell reports (Cambridge) (26.09.2023)
Published in Cell reports (Cambridge) (26.09.2023)
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CD29 identifies IFN-γ–producing human CD8⁺ T cells with an increased cytotoxic potential
Nicolet, Benoît P., Guislain, Aurélie, van Alphen, Floris P. J., Gomez-Eerland, Raquel, Schumacher, Ton N. M., van den Biggelaar, Maartje, Wolkers, Monika C.
Published in Proceedings of the National Academy of Sciences - PNAS (24.03.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (24.03.2020)
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Time-dependent regulation of cytokine production by RNA binding proteins defines T cell effector function
Popović, Branka, Nicolet, Benoît P., Guislain, Aurélie, Engels, Sander, Jurgens, Anouk P., Paravinja, Natali, Freen-van Heeren, Julian J., van Alphen, Floris P.J., van den Biggelaar, Maartje, Salerno, Fiamma, Wolkers, Monika C.
Published in Cell reports (Cambridge) (30.05.2023)
Published in Cell reports (Cambridge) (30.05.2023)
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Human T cells employ conserved AU‐rich elements to fine‐tune IFN‐γ production
Freen‐van Heeren, Julian J., Popović, Branka, Guislain, Aurélie, Wolkers, Monika C.
Published in European journal of immunology (01.07.2020)
Published in European journal of immunology (01.07.2020)
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Journal Article
Polyfunctional tumor-reactive T cells are effectively expanded from non-small cell lung cancers, and correlate with an immune-engaged T cell profile
De Groot, Rosa, Van Loenen, Marleen M., Guislain, Aurélie, Nicolet, Benoît P., Freen-Van Heeren, Julian J., Verhagen, Onno J.H.M., Van Den Heuvel, Michel M., De Jong, Jeroen, Burger, Patrick, Van Der Schoot, C.Ellen, Spaapen, Robbert M., Amsen, Derk, Haanen, John B. A. G., Monkhorst, Kim, Hartemink, Koen J., Wolkers, Monika C.
Published in Oncoimmunology (02.11.2019)
Published in Oncoimmunology (02.11.2019)
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Tertiary lymphoid structure-related immune infiltrates in NSCLC tumor lesions correlate with low tumor-reactivity of TIL products
Castenmiller, Suzanne M, Kanagasabesan, Nandhini, Guislain, Aurélie, Nicolet, Benoît P, van Loenen, Marleen M, Monkhorst, Kim, Veenhof, Alexander A F A, Smit, Egbert F, Hartemink, Koen J, Haanen, John B A G, de Groot, Rosa, Wolkers, Monika C
Published in Oncoimmunology (2024)
Published in Oncoimmunology (2024)
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TLR-Mediated Innate Production of IFN-γ by CD8+ T Cells Is Independent of Glycolysis
Salerno, Fiamma, Guislain, Aurelie, Cansever, Dilay, Wolkers, Monika C
Published in The Journal of immunology (1950) (01.05.2016)
Published in The Journal of immunology (1950) (01.05.2016)
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CD29 Enriches for Cytotoxic Human CD4+ T Cells
Nicolet, Benoît P., Guislain, Aurelie, Wolkers, Monika C.
Published in The Journal of immunology (1950) (15.12.2021)
Published in The Journal of immunology (1950) (15.12.2021)
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Journal Article
Costimulation through TLR2 Drives Polyfunctional CD8 + T Cell Responses
Salerno, Fiamma, Freen-van Heeren, Julian J, Guislain, Aurelie, Nicolet, Benoit P, Wolkers, Monika C
Published in The Journal of immunology (1950) (01.02.2019)
Published in The Journal of immunology (1950) (01.02.2019)
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Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells
Salerno, Fiamma, Engels, Sander, van den Biggelaar, Maartje, van Alphen, Floris P. J., Guislain, Aurelie, Zhao, Wanqi, Hodge, Deborah L., Bell, Sarah E., Medema, Jan Paul, von Lindern, Marieke, Turner, Martin, Young, Howard A., Wolkers, Monika C.
Published in Nature immunology (01.08.2018)
Published in Nature immunology (01.08.2018)
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Sunitinib pretreatment improves tumor-infiltrating lymphocyte expansion by reduction in intratumoral content of myeloid-derived suppressor cells in human renal cell carcinoma
Guislain, Aurelie, Gadiot, Jules, Kaiser, Andrew, Jordanova, Ekaterina S., Broeks, Annegien, Sanders, Joyce, van Boven, Hester, de Gruijl, Tanja D., Haanen, John B. A. G., Bex, Axel, Blank, Christian U.
Published in Cancer Immunology, Immunotherapy (01.10.2015)
Published in Cancer Immunology, Immunotherapy (01.10.2015)
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Single molecule imaging of transcription dynamics, RNA localization and fate in T cells
Lattanzio, Maria Valeria, Sostaric, Nikolina, Kanagasabesan, Nandhini, Popovic, Branka, Bradaric, Antonia, Wardak, Leyma, Guislain, Aurelie, Savakis, Philip E, Tutucci, Evelina, Wolkers, Monika C
Published in bioRxiv (11.11.2024)
Published in bioRxiv (11.11.2024)
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