The pseudosubstrate inhibitor Acm1 inhibits the anaphase-promoting complex/cyclosome by combining high-affinity activator binding with disruption of Doc1/Apc10 function
Qin, Liang, Mizrak, Arda, Guimarães, Dimitrius Santiago P.S.F., Tambrin, Hana M., Morgan, David O., Hall, Mark C.
Published in The Journal of biological chemistry (15.11.2019)
Published in The Journal of biological chemistry (15.11.2019)
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Journal Article
The first evidence of biological activity for free Hypusine, an enigmatic amino acid discovered in the '70s
Tamborlin, Leticia, Pereira, Karina Danielle, Guimarães, Dimitrius Santiago Passos Simões Fróes, Silveira, Leonardo Reis, Luchessi, Augusto Ducati
Published in Amino acids (01.07.2023)
Published in Amino acids (01.07.2023)
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Journal Article
Amino acid restriction alters survival mechanisms in pancreatic beta cells: possible role of the PI3K/Akt pathway
Alves, Bruna Lourençoni, Araújo, Thiago dos Reis, Guimarães, Dimitrius Santiago Passos Simões Fróes, Zoppi, Cláudio Cesar, Figueiredo, Mariana Sarto, Carneiro, Everardo Magalhães
Published in European journal of nutrition (01.10.2021)
Published in European journal of nutrition (01.10.2021)
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Journal Article
Antioxidant effects of LEDT in dystrophic muscle cells: involvement of PGC-1α and UCP-3 pathways
da Rocha, Guilherme Luiz, Guimarães, Dimitrius Santiago Passos Simões Fróes, da Cruz, Marcos Vinicius, Mizobuti, Daniela Sayuri, da Silva, Heloina Nathalliê Mariano, Pereira, Elaine Cristina Leite, Silveira, Leonardo Reis, Minatel, Elaine
Published in Photochemical & photobiological sciences (2024)
Published in Photochemical & photobiological sciences (2024)
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Journal Article
Rosiglitazone protects INS-1E cells from human islet amyloid polypeptide toxicity
Marmentini, Carine, Guimarães, Dimitrius Santiago P.S.F., de Lima, Tanes I., Teófilo, Francisco Breno S., da Silva, Natália S., Soares, Gabriela M., Boschero, Antonio C., Kurauti, Mirian A.
Published in European journal of pharmacology (05.08.2022)
Published in European journal of pharmacology (05.08.2022)
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Journal Article
Regulation of Lin28a-miRNA let-7b-5p pathway in skeletal muscle cells by peroxisome proliferator-activated receptor delta
Araujo, Hygor N., Lima, Tanes I., Guimarães, Dimitrius Santiago P. S. F., Oliveira, Andre G., Favero-Santos, Bianca C., Branco, Renato C. S., da Silva Araújo, Rafaela Mariano, Dantas, Alvaro F. B., Castro, Alex, Chacon-Mikahil, Mara Patrícia T., Minatel, Elaine, Geraldo, Murilo V., Carneiro, Everardo Magalhães, Rodrigues, Alice C., Narkar, Vihang A., Silveira, Leonardo R.
Published in American Journal of Physiology: Cell Physiology (01.09.2020)
Published in American Journal of Physiology: Cell Physiology (01.09.2020)
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Journal Article
Correction to: Amino acid restriction alters survival mechanisms in pancreatic beta cells: possible role of the PI3K/Akt pathway
Alves, Bruna Lourençoni, dos Reis Araújo, Thiago, Guimarães, Dimitrius Santiago Passos Simões Fróes, Zoppi, Cláudio Cesar, Figueiredo, Mariana Sarto, Carneiro, Everardo Magalhães
Published in European journal of nutrition (01.04.2022)
Published in European journal of nutrition (01.04.2022)
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Journal Article
Effects of growth hormone-releasing hormone agonistic analog MR-409 on insulin-secreting cells under cyclopiazonic acid-induced endoplasmic reticulum stress
Rodrigues-dos-Santos, Karina, Soares, Gabriela M., Guimarães, Dimitrius S.P.S.F., Araújo, Thiago R., Vettorazzi, Jean F., Zangerolamo, Lucas, Marconato-Júnior, Emilio, Cai, Renzhi, Sha, Wei, Schally, Andrew V., Boschero, Antônio C., Barbosa, Helena C.L.
Published in Molecular and cellular endocrinology (15.09.2021)
Published in Molecular and cellular endocrinology (15.09.2021)
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Journal Article
Concerted regulation of skeletal muscle metabolism and contractile properties by the orphan nuclear receptor Nr2f6
Guimarães, Dimitrius Santiago P. S. F., Barrios, Ninon M. F., Oliveira, André Gustavo, Rizo‐Roca, David, Jollet, Maxence, Smith, Jonathon A.B., Araujo, Thiago R., Cruz, Marcos Vinicius, Marconato, Emilio, Hirabara, Sandro M., Vieira, André S., Krook, Anna, Zierath, Juleen R., Silveira, Leonardo R.
Published in Journal of cachexia, sarcopenia and muscle (01.08.2024)
Published in Journal of cachexia, sarcopenia and muscle (01.08.2024)
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Journal Article
The recombinant L-lysine α-oxidase from the fungus Trichoderma harzianum promotes apoptosis and necrosis of leukemia CD34 + hematopoietic cells
Costa, Mariana do Nascimento, Silva, Thiago Aparecido, Guimarães, Dimitrius Santiago Passos Simões Fróes, Ricci-Azevedo, Rafael, Teixeira, Felipe Roberti, Silveira, Leonardo Reis, Gomes, Marcelo Damário, Faça, Vítor Marcel, de Oliveira, Eduardo Brandt, Calado, Rodrigo T, Silva, Roberto N
Published in Microbial cell factories (14.02.2024)
Published in Microbial cell factories (14.02.2024)
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Journal Article
Opposing action of NCoR1 and PGC-1α in mitochondrial redox homeostasis
Lima, Tanes I., Guimarães, Dimitrius Santiago P.S.F., Oliveira, André G., Araujo, Hygor, Sponton, Carlos H.G., Souza-Pinto, Nadja C., Saito, Ângela, Figueira, Ana Carolina M., Palameta, Soledad, Bajgelman, Marcio Chaim, Calixto, Andrea, Pinto, Silas, Mori, Marcelo A., Orofino, Joey, Perissi, Valentina, Mottis, Adrienne, Auwerx, Johan, Silveira, Leonardo Reis
Published in Free radical biology & medicine (01.11.2019)
Published in Free radical biology & medicine (01.11.2019)
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Journal Article
The MicroRNA miR-696 is regulated by SNARK and reduces mitochondrial activity in mouse skeletal muscle through Pgc1α inhibition
Queiroz, André L., Lessard, Sarah J., Ouchida, Amanda T., Araujo, Hygor N., Gonçalves, Dawit A., Simões Fróes Guimarães, Dimitrius Santiago P., Teodoro, Bruno G., So, Kawai, Espreafico, Enilza M., Hirshman, Michael F., Alberici, Luciane C., Kettelhut, Isis do Carmo, Goodyear, Laurie J., Silveira, Leonardo R.
Published in Molecular metabolism (Germany) (01.09.2021)
Published in Molecular metabolism (Germany) (01.09.2021)
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Journal Article
Phytomodulatory proteins isolated from Calotropis procera latex promote glycemic control by improving hepatic mitochondrial function in HepG2 cells
Oliveira, Keciany Alves de, Araújo, Hygor Nunes, Lima, Tanes Iamamura de, Oliveira, André Gustavo, Favero-Santos, Bianca Cristine, Guimarães, Dimitrius Santiago P.S.F., Freitas, Paula Alexandre de, Neves, Regina de Jesus das, Vasconcelos, Renata Prado, Almeida, Marina Gabrielle Guimarães de, Ramos, Márcio Viana, Silveira, Leonardo Reis, Oliveira, Ariclecio Cunha de
Published in Saudi pharmaceutical journal (01.09.2021)
Published in Saudi pharmaceutical journal (01.09.2021)
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Journal Article
MicroRNA miR-222 mediates pioglitazone beneficial effects on skeletal muscle of diet-induced obese mice
de Mendonça, Mariana, de Sousa, Érica, da Paixão, Ailma O., Araújo dos Santos, Bruna, Roveratti Spagnol, Alexandre, Murata, Gilson M., Araújo, Hygor N., Imamura de Lima, Tanes, Passos Simões Fróes Guimarães, Dimitrius Santiago, Silveira, Leonardo R., Rodrigues, Alice C.
Published in Molecular and cellular endocrinology (05.02.2020)
Published in Molecular and cellular endocrinology (05.02.2020)
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Journal Article
Differential expression and phytohormone unbalance in Citrus aurantifolia plants during “sudden decline of lime”, a new phytoplasma disease of citrus
Alves, Murilo S., Silva, Fábio N., Guimarães, Dimitrius S. P. S. F., Vital, Camilo E., Vidigal, Pedro M. P., Al-Mahmooli, Issa, Al-Sadi, Abdullah M., Carvalho, Claudine M.
Published in Tropical plant pathology (01.12.2018)
Published in Tropical plant pathology (01.12.2018)
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Journal Article
Essential role of the PGC‐1α/PPARβ axis in Ucp3 gene induction
Lima, Tanes I., Guimarães, Dimitrius, Sponton, Carlos H., Bajgelman, Marcio C., Palameta, Soledad, Toscaro, Jessica M., Reis, Osvaldo, Silveira, Leonardo R.
Published in The Journal of physiology (01.08.2019)
Published in The Journal of physiology (01.08.2019)
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Journal Article
Intramuscular Injection of miR-1 Reduces Insulin Resistance in Obese Mice
Rodrigues, Alice C., Spagnol, Alexandre R., Frias, Flávia de Toledo, de Mendonça, Mariana, Araújo, Hygor N., Guimarães, Dimitrius, Silva, William J., Bolin, Anaysa Paola, Murata, Gilson Masahiro, Silveira, Leonardo
Published in Frontiers in physiology (06.07.2021)
Published in Frontiers in physiology (06.07.2021)
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