Early Alterations of Bile Canaliculi Dynamics and the Rho Kinase/Myosin Light Chain Kinase Pathway Are Characteristics of Drug-Induced Intrahepatic Cholestasis
Burbank, Matthew G, Burban, Audrey, Sharanek, Ahmad, Weaver, Richard J, Guguen-Guillouzo, Christiane, Guillouzo, André
Published in Drug metabolism and disposition (01.11.2016)
Published in Drug metabolism and disposition (01.11.2016)
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Selective bile canalicular changes induced by cholestatic drugs
Burbank, M., Sharanek, A., Burban, A., Weaver, R.J., Guguen-Guillouzo, C., Guillouzo, A.
Published in Toxicology letters (16.10.2015)
Published in Toxicology letters (16.10.2015)
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An adaptation of the human HepaRG cells to the in vitro micronucleus assay
JOSSE, Rozenn, ROGUE, Alexandra, LORGE, Elisabeth, GUILLOUZO, André
Published in Mutagenesis (01.05.2012)
Published in Mutagenesis (01.05.2012)
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Kinetics and dynamics of cyclosporine A in three hepatic cell culture systems
Bellwon, P., Truisi, G.L., Bois, F.Y., Wilmes, A., Schmidt, T., Savary, C.C., Parmentier, C., Hewitt, P.G., Schmal, O., Josse, R., Richert, L., Guillouzo, A., Mueller, S.O., Jennings, P., Testai, E., Dekant, W.
Published in Toxicology in vitro (25.12.2015)
Published in Toxicology in vitro (25.12.2015)
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Amiodarone-induced phospholipidosis and steatosis in human hepatoma HepaRG cells
Anthérieu, S., Fromenty, B., Robin, M.A., Guillouzo, A.
Published in Toxicology letters (17.07.2010)
Published in Toxicology letters (17.07.2010)
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Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture
ZIAD ABDEL-RAZZAK, LOYER, P, FAUTREL, A, GAUTIER, J.-C, CORCOS, L, TURLIN, B, BEAUNE, P, GUILLOUZO, A
Published in Molecular pharmacology (01.10.1993)
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Published in Molecular pharmacology (01.10.1993)
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The sulphonylurea glibenclamide inhibits multidrug resistance protein (MRP1) activity in human lung cancer cells
Payen, Léa, Delugin, Laurence, Courtois, Arnaud, Trinquart, Yolande, Guillouzo, André, Fardel, Olivier
Published in British journal of pharmacology (01.02.2001)
Published in British journal of pharmacology (01.02.2001)
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Opposite regulation of human versus mouse apolipoprotein A-I by fibrates in human apolipoprotein A-I transgenic mice
Berthou, L, Duverger, N, Emmanuel, F, Langouët, S, Auwerx, J, Guillouzo, A, Fruchart, J C, Rubin, E, Denèfle, P, Staels, B, Branellec, D
Published in The Journal of clinical investigation (01.06.1996)
Published in The Journal of clinical investigation (01.06.1996)
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Reactive Oxygen Species-Related Induction of Multidrug Resistance-Associated Protein 2 Expression in Primary Hepatocytes Exposed to Sulforaphane
Payen, Léa, Courtois, Arnaud, Loewert, Maud, Guillouzo, André, Fardel, Olivier
Published in Biochemical and biophysical research communications (23.03.2001)
Published in Biochemical and biophysical research communications (23.03.2001)
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Metabolism of Meloxicam in human liver involves cytochromes P4502C9 and 3A4
CHESNE, C., GUYOMARD, C., GUILLOUZO, A., SCHMID, J., LUDWIG, E., SAUTER, T.
Published in Xenobiotica (1998)
Published in Xenobiotica (1998)
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Metabolism of 2-Amino-3,8-dimethylimidazo[4,5-f]- quinoxaline in Human Hepatocytes: 2-Amino-3-methylimidazo[4,5-f]quinoxaline-8-carboxylic Acid Is a Major Detoxication Pathway Catalyzed by Cytochrome P450 1A2
Langouët, Sophie, Welti, Dieter H, Kerriguy, Nathalie, Fay, Laurent B, Huynh-Ba, Tuong, Markovic, Jovanka, Guengerich, F. Peter, Guillouzo, André, Turesky, Robert J
Published in Chemical research in toxicology (19.02.2001)
Published in Chemical research in toxicology (19.02.2001)
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Dysregulation of defence systems by 5-fluorouracil in colon cancer HT-29 cells
Akhdar, H, Loyer, P, Rauch, C, Guillouzo, A, Morel, F
Published in European journal of cancer supplements (2008)
Published in European journal of cancer supplements (2008)
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496 POSTER Regulation of Nrf2-antioxidant system and glutathione transferases by 5-fluorouracil in colon cancer HT-29 cells: potential implication in drug resistance
Akhdar, H, Loyer, P, Rauch, C, Guillouzo, A, Morel, F
Published in European journal of cancer supplements (2008)
Published in European journal of cancer supplements (2008)
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