The E3 ubiquitin ligase TRIP12 is required for pancreatic acinar cell plasticity and pancreatic carcinogenesis
Brunet, Manon, Vargas, Claire, Fanjul, Marjorie, Varry, Damien, Hanoun, Naïma, Larrieu, Dorian, Pieruccioni, Laetitia, Labrousse, Guillaume, Lulka, Hubert, Capilla, Florence, Ricard, Alban, Selves, Janick, Couvelard, Anne, Gigoux, Véronique, Cordelier, Pierre, Guillermet‐Guibert, Julie, Dufresne, Marlène, Torrisani, Jérôme
Published in The Journal of pathology (01.08.2024)
Published in The Journal of pathology (01.08.2024)
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Journal Article
p110β isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110γ
Guillermet-Guibert, Julie, Bjorklof, Katja, Salpekar, Ashreena, Gonella, Cristiano, Ramadani, Faruk, Bilancio, Antonio, Meek, Stephen, Smith, Andrew J.H, Okkenhaug, Klaus, Vanhaesebroeck, Bart
Published in Proceedings of the National Academy of Sciences - PNAS (17.06.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (17.06.2008)
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Journal Article
Upregulated Apelin Signaling in Pancreatic Cancer Activates Oncogenic Signaling Pathways to Promote Tumor Development
Chaves-Almagro, Carline, Auriau, Johanna, Dortignac, Alizée, Clerc, Pascal, Lulka, Hubert, Deleruyelle, Simon, Projetti, Fabrice, Nakhlé, Jessica, Frances, Audrey, Berta, Judit, Gigoux, Véronique, Fourmy, Daniel, Dufresne, Marlène, Gomez-Brouchet, Anne, Guillermet-Guibert, Julie, Cordelier, Pierre, Knibiehler, Bernard, Jockers, Ralf, Valet, Philippe, Audigier, Yves, Masri, Bernard
Published in International journal of molecular sciences (13.09.2022)
Published in International journal of molecular sciences (13.09.2022)
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Journal Article
Hypoxia Induces VEGF-C Expression in Metastatic Tumor Cells via a HIF-1α-Independent Translation-Mediated Mechanism
Morfoisse, Florent, Kuchnio, Anna, Frainay, Clement, Gomez-Brouchet, Anne, Delisle, Marie-Bernadette, Marzi, Stefano, Helfer, Anne-Catherine, Hantelys, Fransky, Pujol, Francoise, Guillermet-Guibert, Julie, Bousquet, Corinne, Dewerchin, Mieke, Pyronnet, Stephane, Prats, Anne-Catherine, Carmeliet, Peter, Garmy-Susini, Barbara
Published in Cell reports (Cambridge) (01.01.2014)
Published in Cell reports (Cambridge) (01.01.2014)
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Journal Article
Somatostatin Receptor Subtype 2 Sensitizes Human Pancreatic Cancer Cells to Death Ligand-Induced Apoptosis
Guillermet, Julie, Saint-Laurent, Nathalie, Rochaix, Philippe, Cuvillier, Olivier, Levade, Thierry, Schally, Andrew V., Pradayrol, Lucien, Buscail, Louis, Susini, Christiane, Bousquet, Corinne
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2003)
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Journal Article
Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells
Guillermet-Guibert, Julie, Smith, Lee B, Halet, Guillaume, Whitehead, Maria A, Pearce, Wayne, Rebourcet, Diane, León, Kelly, Crépieux, Pascale, Nock, Gemma, Strömstedt, Maria, Enerback, Malin, Chelala, Claude, Graupera, Mariona, Carroll, John, Cosulich, Sabina, Saunders, Philippa T K, Huhtaniemi, Ilpo, Vanhaesebroeck, Bart
Published in PLoS genetics (01.07.2015)
Published in PLoS genetics (01.07.2015)
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Journal Article
Targeting the sphingolipid metabolism to defeat pancreatic cancer cell resistance to the chemotherapeutic gemcitabine drug
Guillermet-Guibert, Julie, Davenne, Lise, Pchejetski, Dimitri, Saint-Laurent, Nathalie, Brizuela, Leyre, Guilbeau-Frugier, Céline, Delisle, Marie-Bernadette, Cuvillier, Olivier, Susini, Christiane, Bousquet, Corinne
Published in Molecular cancer therapeutics (01.04.2009)
Published in Molecular cancer therapeutics (01.04.2009)
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Journal Article
Pancreatic preneoplastic lesions plasma signatures and biomarkers based on proteome profiling of mouse models
Ligat, Laetitia, Saint-Laurent, Nathalie, El-Mrani, Aïcha, Gigoux, Véronique, Al Saati, Talal, Tomasini, Richard, Nigri, Jérémy, Dejean, Sébastien, Pont, Frédéric, Baer, Romain, Guillermet-Guibert, Julie, Cordelier, Pierre, Lopez, Frédéric, Dufresne, Marlène
Published in British journal of cancer (01.12.2015)
Published in British journal of cancer (01.12.2015)
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Journal Article
Acinar-to-Ductal Metaplasia Induced by Transforming Growth Factor Beta Facilitates KRAS G12D -driven Pancreatic Tumorigenesis
Chuvin, Nicolas, Vincent, David F, Pommier, Roxane M, Alcaraz, Lindsay B, Gout, Johann, Caligaris, Cassandre, Yacoub, Karam, Cardot, Victoire, Roger, Elodie, Kaniewski, Bastien, Martel, Sylvie, Cintas, Celia, Goddard-Léon, Sophie, Colombe, Amélie, Valantin, Julie, Gadot, Nicolas, Servoz, Emilie, Morton, Jennifer, Goddard, Isabelle, Couvelard, Anne, Rebours, Vinciane, Guillermet, Julie, Sansom, Owen J, Treilleux, Isabelle, Valcourt, Ulrich, Sentis, Stéphanie, Dubus, Pierre, Bartholin, Laurent
Published in Cellular and molecular gastroenterology and hepatology (01.09.2017)
Published in Cellular and molecular gastroenterology and hepatology (01.09.2017)
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Journal Article
Direct binding of p85 to sst2 somatostatin receptor reveals a novel mechanism for inhibiting PI3K pathway
Bousquet, Corinne, Guillermet-Guibert, Julie, Saint-Laurent, Nathalie, Archer-Lahlou, Elodie, Lopez, Frédéric, Fanjul, Marjorie, Ferrand, Audrey, Fourmy, Daniel, Pichereaux, Carole, Monsarrat, Bernard, Pradayrol, Lucien, Estève, Jean-Pierre, Susini, Christiane
Published in The EMBO journal (06.09.2006)
Published in The EMBO journal (06.09.2006)
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Mechanistic target of rapamycin (mTOR) regulates self-sustained quiescence, tumor indolence, and late clinical metastasis in a Beclin-1-dependent manner
Nicco, Carole, Thomas, Marine, Guillermet, Julie, Havard, Maryline, Laurent-Tchenio, Fanny, Doridot, Ludivine, Dautry, François, Batteux, Frédéric, Tchenio, Thierry
Published in Cell cycle (Georgetown, Tex.) (04.03.2023)
Published in Cell cycle (Georgetown, Tex.) (04.03.2023)
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Journal Article
The emerging mechanisms of isoform-specific PI3K signalling
Vanhaesebroeck, Bart, Guillermet-Guibert, Julie, Graupera, Mariona, Bilanges, Benoit
Published in Nature reviews. Molecular cell biology (01.05.2010)
Published in Nature reviews. Molecular cell biology (01.05.2010)
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Journal Article
Molecular Signaling of Somatostatin Receptors
LAHLOU, HICHAM, GUILLERMET, JULIE, HORTALA, MARYLIS, VERNEJOUL, FABIENNE, PYRONNET, STÉPHANE, BOUSQUET, CORINNE, SUSINI, CHRISTIANE
Published in Annals of the New York Academy of Sciences (01.04.2004)
Published in Annals of the New York Academy of Sciences (01.04.2004)
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Journal Article
Rôle spécifique de la PI3kinase alpha hépatocytaire : influence sur le diabète et la stéatose hépatique
Regnier, Marion, Polizzi, Arnaud, Lukowicz, Céline, Fouché, Edwin, Lasserre, Frédéric, Lippi, Yannick, Bertrand-Michel, Justine, Guillermet, Julie, Loiseau, Nicolas, Postic, Catherine, Montagner, Alexandra, Guillou, Hervé
Published in Diabetes & metabolism (01.03.2017)
Published in Diabetes & metabolism (01.03.2017)
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Journal Article
The type of KRAS mutation drives PI3Kα/γ signalling dependency: Implication for the choice of targeted therapy in pancreatic adenocarcinoma patients
Cayron, Coralie, Guillermet-Guibert, Julie
Published in Clinics and research in hepatology and gastroenterology (01.01.2021)
Published in Clinics and research in hepatology and gastroenterology (01.01.2021)
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Journal Article
Targeting PI3K Signaling in Combination Cancer Therapy
Pons-Tostivint, Elvire, Thibault, Benoît, Guillermet-Guibert, Julie
Published in Trends in cancer (01.06.2017)
Published in Trends in cancer (01.06.2017)
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