Activation-Induced Cytidine Deaminase-Dependent DNA Breaks in Class Switch Recombination Occur during G1 Phase of the Cell Cycle and Depend upon Mismatch Repair
Schrader, Carol E, Guikema, Jeroen E. J, Linehan, Erin K, Selsing, Erik, Stavnezer, Janet
Published in The Journal of immunology (1950) (01.11.2007)
Published in The Journal of immunology (1950) (01.11.2007)
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Systematic evaluation of B-cell clonal family inference approaches
Balashova, Daria, van Schaik, Barbera D C, Stratigopoulou, Maria, Guikema, Jeroen E J, Caniels, Tom G, Claireaux, Mathieu, van Gils, Marit J, Musters, Anne, Anang, Dornatien C, de Vries, Niek, Greiff, Victor, van Kampen, Antoine H C
Published in BMC immunology (08.02.2024)
Published in BMC immunology (08.02.2024)
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The DNA Damage Response Regulates RAG1/2 Expression in Pre-B Cells through ATM-FOXO1 Signaling
Ochodnicka-Mackovicova, Katarina, Bahjat, Mahnoush, Maas, Chiel, van der Veen, Amélie, Bloedjes, Timon A, de Bruin, Alexander M, van Andel, Harmen, Schrader, Carol E, Hendriks, Rudi W, Verhoeyen, Els, Bende, Richard J, van Noesel, Carel J M, Guikema, Jeroen E J
Published in The Journal of immunology (1950) (01.10.2016)
Published in The Journal of immunology (1950) (01.10.2016)
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Understanding repertoire sequencing data through a multiscale computational model of the germinal center
García-Valiente, Rodrigo, Merino Tejero, Elena, Stratigopoulou, Maria, Balashova, Daria, Jongejan, Aldo, Lashgari, Danial, Pélissier, Aurélien, Caniels, Tom G., Claireaux, Mathieu A. F., Musters, Anne, van Gils, Marit J., Rodríguez Martínez, María, de Vries, Niek, Meyer-Hermann, Michael, Guikema, Jeroen E. J., Hoefsloot, Huub, van Kampen, Antoine H. C.
Published in NPJ systems biology and applications (16.03.2023)
Published in NPJ systems biology and applications (16.03.2023)
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Base Excision Repair in the Immune System: Small DNA Lesions With Big Consequences
Stratigopoulou, Maria, van Dam, Tijmen P, Guikema, Jeroen E J
Published in Frontiers in immunology (29.05.2020)
Published in Frontiers in immunology (29.05.2020)
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Mechanism and regulation of class switch recombination
Stavnezer, Janet, Guikema, Jeroen E J, Schrader, Carol E
Published in Annual review of immunology (01.01.2008)
Published in Annual review of immunology (01.01.2008)
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Core regions in immunoglobulin heavy chain enhancers essential for survival of non-Hodgkin lymphoma cells are identified by a CRISPR interference screen
Kasprzyk, Marta Elżbieta, Sura, Weronika, Podralska, Marta, Kazimierska, Marta, Seitz, Annika, Łosiewski, Wojciech, Woźniak, Tomasz, Guikema, Jeroen E J, Diepstra, Arjan, Kluiver, Joost, Van den Berg, Anke, Rozwadowska, Natalia, Dzikiewicz-Krawczyk, Agnieszka
Published in Haematologica (Roma) (27.06.2024)
Published in Haematologica (Roma) (27.06.2024)
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Apurinic/apyrimidinic endonuclease 2 is necessary for normal B cell development and recovery of lymphoid progenitors after chemotherapeutic challenge
Guikema, Jeroen E J, Gerstein, Rachel M, Linehan, Erin K, Cloherty, Erin K, Evan-Browning, Eric, Tsuchimoto, Daisuke, Nakabeppu, Yusaku, Schrader, Carol E
Published in The Journal of immunology (1950) (15.02.2011)
Published in The Journal of immunology (1950) (15.02.2011)
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RAG1/2 induces double‐stranded DNA breaks at non‐Ig loci in the proximity of single sequence repeats in developing B cells
Ochodnicka‐Mackovicova, Katarina, Mokry, Michal, Haagmans, Martin, Bradley, Ted E., Noesel, Carel J.M., Guikema, Jeroen E.J.
Published in European journal of immunology (01.10.2024)
Published in European journal of immunology (01.10.2024)
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A mutated B cell chronic lymphocytic leukemia subset that recognizes and responds to fungi
Hoogeboom, Robbert, van Kessel, Kok P M, Hochstenbach, Frans, Wormhoudt, Thera A, Reinten, Roy J A, Wagner, Koen, Kater, Arnon P, Guikema, Jeroen E J, Bende, Richard J, van Noesel, Carel J M
Published in The Journal of experimental medicine (14.01.2013)
Published in The Journal of experimental medicine (14.01.2013)
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Multiscale Modeling of Germinal Center Recapitulates the Temporal Transition From Memory B Cells to Plasma Cells Differentiation as Regulated by Antigen Affinity-Based Tfh Cell Help
Merino Tejero, Elena, Lashgari, Danial, García-Valiente, Rodrigo, Gao, Xuefeng, Crauste, Fabien, Robert, Philippe A, Meyer-Hermann, Michael, Martínez, María Rodríguez, van Ham, S Marieke, Guikema, Jeroen E J, Hoefsloot, Huub, van Kampen, Antoine H C
Published in Frontiers in immunology (05.02.2021)
Published in Frontiers in immunology (05.02.2021)
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Huwe1 supports B-cell development, B-cell-dependent immunity, somatic hypermutation and class switch recombination by regulating proliferation
Spanjaard, Aldo, Stratigopoulou, Maria, de Groot, Daniël, Aslam, Muhammad, van den Berk, Paul C M, Stappenbelt, Chantal, Ayidah, Matilda, Catsman, Joyce J I, Pardieck, Iris N, Kreft, Maaike, Arens, Ramon, Guikema, Jeroen E J, Jacobs, Heinz
Published in Frontiers in immunology (09.01.2023)
Published in Frontiers in immunology (09.01.2023)
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Coupled Antigen and BLIMP1 Asymmetric Division With a Large Segregation Between Daughter Cells Recapitulates the Temporal Transition From Memory B Cells to Plasma Cells and a DZ-to-LZ Ratio in the Germinal Center
Merino Tejero, Elena, Lashgari, Danial, García-Valiente, Rodrigo, He, Jiaojiao, Robert, Philippe A, Meyer-Hermann, Michael, Guikema, Jeroen E J, Hoefsloot, Huub, van Kampen, Antoine H C
Published in Frontiers in immunology (17.08.2021)
Published in Frontiers in immunology (17.08.2021)
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SMG1, a nonsense‐mediated mRNA decay (NMD) regulator, as a candidate therapeutic target in multiple myeloma
Leeksma, Alexander C., Derks, Ingrid A. M., Garrick, Brett, Jongejan, Aldo, Colombo, Martino, Bloedjes, Timon, Trowe, Torsten, Leisten, Jim C., Howarth, Michelle, Malek, Mehnaz, Mortensen, Deborah S., Blease, Kate, Groza, Mathew C., Narla, Rama Krishna, Loos, Remco, Kersten, Marie‐José, Moerland, Perry D., Guikema, Jeroen E. J., Kater, Arnon P., Eldering, Eric, Filvaroff, Ellen H.
Published in Molecular oncology (01.02.2023)
Published in Molecular oncology (01.02.2023)
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Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins
van Andel, Harmen, Ren, Zemin, Koopmans, Iris, Joosten, Sander P. J., Kocemba, Kinga A., de Lau, Wim, Kersten, Marie José, de Bruin, Alexander M., Guikema, Jeroen E. J., Clevers, Hans, Spaargaren, Marcel, Pals, Steven T.
Published in Proceedings of the National Academy of Sciences - PNAS (10.01.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (10.01.2017)
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AKT signaling restrains tumor suppressive functions of FOXO transcription factors and GSK3 kinase in multiple myeloma
Bloedjes, Timon A., de Wilde, Guus, Maas, Chiel, Eldering, Eric, Bende, Richard J., van Noesel, Carel J.M., Pals, Steven T., Spaargaren, Marcel, Guikema, Jeroen E.J.
Published in Blood advances (08.09.2020)
Published in Blood advances (08.09.2020)
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APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination
Guikema, Jeroen E J, Linehan, Erin K, Tsuchimoto, Daisuke, Nakabeppu, Yusaku, Strauss, Phyllis R, Stavnezer, Janet, Schrader, Carol E
Published in The Journal of experimental medicine (26.11.2007)
Published in The Journal of experimental medicine (26.11.2007)
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Computational Model Reveals Limited Correlation between Germinal Center B-Cell Subclone Abundancy and Affinity: Implications for Repertoire Sequencing
Reshetova, Polina, van Schaik, Barbera D C, Klarenbeek, Paul L, Doorenspleet, Marieke E, Esveldt, Rebecca E E, Tak, Paul-Peter, Guikema, Jeroen E J, de Vries, Niek, van Kampen, Antoine H C
Published in Frontiers in immunology (06.03.2017)
Published in Frontiers in immunology (06.03.2017)
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