Immunization with germ line-targeting SOSIP trimers elicits broadly neutralizing antibody precursors in infant macaques
Nelson, Ashley N, Shen, Xiaoying, Vekatayogi, Sravani, Zhang, Shiyu, Ozorowski, Gabriel, Dennis, Maria, Sewall, Leigh M, Milligan, Emma, Davis, Dominique, Cross, Kaitlyn A, Chen, Yue, van Schooten, Jelle, Eudailey, Joshua, Isaac, John, Memon, Saad, Weinbaum, Carolyn, Gao, Hongmei, Stanfield-Oakley, Sherry, Byrd, Alliyah, Chutkan, Suni, Berendam, Stella, Cronin, Kenneth, Yasmeen, Anila, Alam, S, LaBranche, Celia C, Rogers, Kenneth, Shirreff, Lisa, Cupo, Albert, Derking, Ronald, Villinger, Francois, Klasse, Per Johan, Ferrari, Guido, Williams, Wilton B, Hudgens, Michael G, Ward, Andrew B, Montefiori, David C, Van Rompay, Koen K A, Wiehe, Kevin, Moore, John P, Sanders, Rogier W, De Paris, Kristina, Permar, Sallie R
Published in Science immunology (30.08.2024)
Published in Science immunology (30.08.2024)
Get more information
Journal Article
Safety and immunogenicity after a 30-month boost of a subtype C ALVAC-HIV (vCP2438) vaccine prime plus bivalent subtype C gp120/MF59 vaccine boost (HVTN 100): A phase 1-2 randomized double-blind placebo-controlled trial
Naicker, Vimla, Laher, Fatima, Bekker, Linda-Gail, Seaton, Kelly E, Allen, Mary, De Rosa, Stephen, Yates, Nicole L, Mkhize, Nonhlanhla N, Saunders, Kevin, Heptinstall, Jack, Malahleha, Mookho, Mngadi, Kathryn, Daniels, Brodie, Innes, Craig, Yu, Chenchen, Modise, Tandile, Bekker, Valerie, Grunenberg, Nicole, Furch, Briana, Miner, Maurine D, Phogat, Sanjay, Diazgranados, Carlos A, Gurunathan, Sanjay, Koutsoukos, Marguerite, Van Der Meeren, Olivier, Roxby, Alison C, Ferrari, Guido, Morris, Lynn, Montefiori, David, McElrath, M Juliana, Tomaras, Georgia D, Moodie, Zoe
Published in PLOS global public health (2024)
Published in PLOS global public health (2024)
Get full text
Journal Article
Neutralization Takes Precedence Over IgG or IgA Isotype-related Functions in Mucosal HIV-1 Antibody-mediated Protection
Astronomo, Rena D., Santra, Sampa, Ballweber-Fleming, Lamar, Westerberg, Katharine G., Mach, Linh, Hensley-McBain, Tiffany, Sutherland, Laura, Mildenberg, Benjamin, Morton, Georgeanna, Yates, Nicole L., Mize, Gregory J., Pollara, Justin, Hladik, Florian, Ochsenbauer, Christina, Denny, Thomas N., Warrier, Ranjit, Rerks-Ngarm, Supachai, Pitisuttithum, Punnee, Nitayapan, Sorachai, Kaewkungwal, Jaranit, Ferrari, Guido, Shaw, George M., Xia, Shi-Mao, Liao, Hua-Xin, Montefiori, David C., Tomaras, Georgia D., Haynes, Barton F., McElrath, M. Juliana
Published in EBioMedicine (01.12.2016)
Published in EBioMedicine (01.12.2016)
Get full text
Journal Article
Control of Heterologous Simian Immunodeficiency Virus SIV smE660 Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based Adjuvants in Macaques
Singh, Shakti, Ramírez-Salazar, Eric G, Doueiri, Rami, Valentin, Antonio, Rosati, Margherita, Hu, Xintao, Keele, Brandon F, Shen, Xiaoying, Tomaras, Georgia D, Ferrari, Guido, LaBranche, Celia, Montefiori, David C, Das, Jishnu, Alter, Galit, Trinh, Hung V, Hamlin, Christopher, Rao, Mangala, Dayton, Frances, Bear, Jenifer, Chowdhury, Bhabadeb, Alicea, Candido, Lifson, Jeffrey D, Broderick, Kate E, Sardesai, Niranjan Y, Sivananthan, Sandra J, Fox, Christopher B, Reed, Steven G, Venzon, David J, Hirsch, Vanessa M, Pavlakis, George N, Felber, Barbara K
Published in Journal of virology (01.08.2018)
Published in Journal of virology (01.08.2018)
Get full text
Journal Article
In Vivo Treatment with Insulin-like Growth Factor 1 Reduces CCR5 Expression on Vaccine-Induced Activated CD4 + T-Cells
Bissa, Massimiliano, Galli, Veronica, Schifanella, Luca, Vaccari, Monica, Rahman, Mohammad Arif, Gorini, Giacomo, Binello, Nicolò, Sarkis, Sarkis, Gutowska, Anna, Silva de Castro, Isabela, Doster, Melvin N, Moles, Ramona, Ferrari, Guido, Shen, Xiaoying, Tomaras, Georgia D, Montefiori, David C, N'guessan, Kombo F, Paquin-Proulx, Dominic, Kozlowski, Pamela A, Venzon, David J, Choo-Wosoba, Hyoyoung, Breed, Matthew W, Kramer, Joshua, Franchini, Genoveffa
Published in Vaccines (Basel) (30.10.2023)
Published in Vaccines (Basel) (30.10.2023)
Get full text
Journal Article
A phase I trial of preventive HIV vaccination with heterologous poxviral-vectors containing matching HIV-1 inserts in healthy HIV-uninfected subjects
Keefer, Michael C, Frey, Sharon E, Elizaga, Marnie, Metch, Barbara, De Rosa, Stephen C, Barroso, Paulo F, Tomaras, Georgia, Cardinali, Massimo, Goepfert, Paul, Kalichman, Artur, Philippon, Valérie, McElrath, M. Juliana, Jin, Xia, Ferrari, Guido, Defawe, Olivier D, Mazzara, Gail P, Montefiori, David, Pensiero, Michael, Panicali, Dennis L, Corey, Lawrence
Published in Vaccine (24.02.2011)
Published in Vaccine (24.02.2011)
Get full text
Journal Article
Mucosal Immunization of Lactating Female Rhesus Monkeys with a Transmitted/Founder HIV-1 Envelope Induces Strong Env-Specific IgA Antibody Responses in Breast Milk
Fouda, Genevieve G A, Amos, Joshua D, Wilks, Andrew B, Pollara, Justin, Ray, Caroline A, Chand, Anjali, Kunz, Erika L, Liebl, Brooke E, Whitaker, Kaylan, Carville, Angela, Smith, Shannon, Colvin, Lisa, Pickup, David J, Staats, Herman F, Overman, Glenn, Eutsey-Lloyd, Krissey, Parks, Robert, Chen, Haiyan, Labranche, Celia, Barnett, Susan, Tomaras, Georgia D, Ferrari, Guido, Montefiori, David C, Liao, Hua-Xin, Letvin, Norman L, Haynes, Barton F, Permar, Sallie R
Published in Journal of Virology (01.06.2013)
Published in Journal of Virology (01.06.2013)
Get full text
Journal Article
Characterization of a vaccine-elicited human antibody with sequence homology to VRC01-class antibodies that binds the C1C2 gp120 domain
Gray, Matthew D, Feng, Junli, Weidle, Connor E, Cohen, Kristen W, Ballweber-Fleming, Lamar, MacCamy, Anna J, Huynh, Crystal N, Trichka, Josephine J, Montefiori, David, Ferrari, Guido, Pancera, Marie, McElrath, M Juliana, Stamatatos, Leonidas
Published in Science advances (06.05.2022)
Published in Science advances (06.05.2022)
Get full text
Journal Article
Optimization of storage and shipment of cryopreserved peripheral blood mononuclear cells from HIV-infected and uninfected individuals for ELISPOT assays
Weinberg, Adriana, Song, Lin Ye, Wilkening, Cindy L., Fenton, Terry, Hural, John, Louzao, Raul, Ferrari, Guido, Etter, Paige E., Berrong, Mark, Canniff, Jennifer D., Carter, Donald, Defawe, Olivier D., Garcia, Ambrosia, Garrelts, Tania L., Gelman, Rebecca, Lambrecht, Linda K., Pahwa, Savita, Pilakka-Kanthikeel, Sudheesh, Shugarts, David L., Tustin, Nancy B.
Published in Journal of immunological methods (15.12.2010)
Published in Journal of immunological methods (15.12.2010)
Get full text
Journal Article
Vaccine-induced HIV-1 envelope gp120 constant region 1-specific antibodies expose a CD4-inducible epitope and block the interaction of HIV-1 gp140 with galactosylceramide
Dennison, S Moses, Anasti, Kara M, Jaeger, Frederick H, Stewart, Shelley M, Pollara, Justin, Liu, Pinghuang, Kunz, Erika L, Zhang, Ruijun, Vandergrift, Nathan, Permar, Sallie, Ferrari, Guido, Tomaras, Georgia D, Bonsignori, Mattia, Michael, Nelson L, Kim, Jerome H, Kaewkungwal, Jaranit, Nitayaphan, Sorachai, Pitisuttithum, Punnee, Rerks-Ngarm, Supachai, Liao, Hua-Xin, Haynes, Barton F, Alam, S Munir
Published in Journal of virology (01.08.2014)
Published in Journal of virology (01.08.2014)
Get full text
Journal Article
Loss of DNAM-1 contributes to CD8⁺ T-cell exhaustion in chronic HIV-1 infection
Cella, Marina, Presti, Rachel, Vermi, William, Lavender, Kerry, Turnbull, Emma, Ochsenbauer-Jambor, Christina, Kappes, John C, Ferrari, Guido, Kessels, Lisa, Williams, Ian, McMichael, Andrew J, Haynes, Barton F, Borrow, Persephone, Colonna, Marco
Published in European journal of immunology (01.04.2010)
Published in European journal of immunology (01.04.2010)
Get full text
Journal Article
Boosting of HIV envelope CD4 binding site with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial
Easterhoff, David, Moody, M. Anthony, Fera, Daniela, Cheng, Hao, Ackerman, Margaret, Wiehe, Kevin, Saunders, Kevin O, Pollara, Justin, Vandergrift, Nathan, Parks, Rob, Kim, Jerome, Michael, Nelson L, O'Connell, Robert J, Excler, Jean-Louis, Robb, Merlin L, Vasan, Sandhya, Rerks-Ngarm, Supachai, Kaewkungwal, Jaranit, Pitisuttithum, Punnee, Nitayaphan, Sorachai, Sinangil, Faruk, Tartaglia, James, Phogat, Sanjay, Kepler, Thomas B, Alam, S. Munir, Liao, Hua-Xin, Ferrari, Guido, Seaman, Michael S, Montefiori, David C, Tomaras, Georgia D, Harrison, Stephen C, Haynes, Barton F
Published in PLoS pathogens (24.02.2017)
Published in PLoS pathogens (24.02.2017)
Get full text
Journal Article
The Center for HIV/AIDS Vaccine Immunology (CHAVI) multi-site quality assurance program for cryopreserved Human Peripheral Blood Mononuclear Cells
Sarzotti-Kelsoe, Marcella, Needham, Leila K., Rountree, Wes, Bainbridge, John, Gray, Clive M., Fiscus, Susan A., Ferrari, Guido, Stevens, Wendy S., Stager, Susan L., Binz, Whitney, Louzao, Raul, Long, Kristy O., Mokgotho, Pauline, Moodley, Niranjini, Mackay, Melanie, Kerkau, Melissa, McMillion, Takesha, Kirchherr, Jennifer, Soderberg, Kelly A., Haynes, Barton F., Denny, Thomas N.
Published in Journal of immunological methods (01.07.2014)
Published in Journal of immunological methods (01.07.2014)
Get full text
Journal Article
Distinct kinetics of Gag-specific CD4+ and CD8+ T cell responses during acute HIV-1 infection
Riou, Catherine, Ganusov, Vitaly V, Campion, Suzanne, Mlotshwa, Mandla, Liu, Michael K P, Whale, Victoria E, Goonetilleke, Nilu, Borrow, Persephone, Ferrari, Guido, Betts, Michael R, Haynes, Barton F, McMichael, Andrew J, Gray, Clive M
Published in The Journal of immunology (1950) (01.03.2012)
Published in The Journal of immunology (1950) (01.03.2012)
Get full text
Journal Article
BISPECIFIC DIABODY MOLECULES, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF
SCOTT KOENIG, JOHNSON LESLIE S, GUIDO FERRARI, BARTON F HAYNES, LIU LIQIN, CHIA-YING KAO LAM, JEFFREY LEE NORDSTROM
Year of Publication 09.04.2020
Get full text
Year of Publication 09.04.2020
Patent
Anti-V2 antibodies virus vulnerability revealed by envelope V1 deletion in HIV vaccine candidates
Silva de Castro, Isabela, Gorini, Giacomo, Mason, Rosemarie, Gorman, Jason, Bissa, Massimiliano, Rahman, Mohammad A., Arakelyan, Anush, Kalisz, Irene, Whitney, Stephen, Becerra-Flores, Manuel, Ni, Eric, Peachman, Kristina, Trinh, Hung V., Read, Michael, Liu, Mei-Hue, Van Ryk, Donald, Paquin-Proulx, Dominic, Shubin, Zhanna, Tuyishime, Marina, Peele, Jennifer, Ahmadi, Mohammed S., Verardi, Raffaello, Hill, Juliane, Beddall, Margaret, Nguyen, Richard, Stamos, James D., Fujikawa, Dai, Min, Susie, Schifanella, Luca, Vaccari, Monica, Galli, Veronica, Doster, Melvin N., Liyanage, Namal P.M., Sarkis, Sarkis, Caccuri, Francesca, LaBranche, Celia, Montefiori, David C., Tomaras, Georgia D., Shen, Xiaoying, Rosati, Margherita, Felber, Barbara K., Pavlakis, George N., Venzon, David J., Magnanelli, William, Breed, Matthew, Kramer, Josh, Keele, Brandon F., Eller, Michael A., Cicala, Claudia, Arthos, James, Ferrari, Guido, Margolis, Leonid, Robert-Guroff, Marjorie, Kwong, Peter D., Roederer, Mario, Rao, Mangala, Cardozo, Timothy J., Franchini, Genoveffa
Published in iScience (19.02.2021)
Published in iScience (19.02.2021)
Get full text
Journal Article
Identification of Effective Subdominant Anti-HIV-1 CD8+ T Cells Within Entire Post-infection and Post-vaccination Immune Responses: e1004658
Hancock, Gemma, Yang, Hongbing, Yorke, Elisabeth, Wainwright, Emma, Bourne, Victoria, Frisbee, Alyse, Payne, Tamika L, Berrong, Mark, Ferrari, Guido, Chopera, Denis, Hanke, Tomas, Mothe, Beatriz, Brander, Christian, McElrath, M Juliana, McMichael, Andrew, Goonetilleke, Nilu, Tomaras, Georgia D, Frahm, Nicole, Dorrell, Lucy
Published in PLoS pathogens (01.02.2015)
Published in PLoS pathogens (01.02.2015)
Get full text
Journal Article