Targeting Metabolism for Cancer Therapy
Luengo, Alba, Gui, Dan Y., Vander Heiden, Matthew G.
Published in Cell chemical biology (21.09.2017)
Published in Cell chemical biology (21.09.2017)
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Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells
Lewis, Caroline A., Parker, Seth J., Fiske, Brian P., McCloskey, Douglas, Gui, Dan Y., Green, Courtney R., Vokes, Natalie I., Feist, Adam M., Vander Heiden, Matthew G., Metallo, Christian M.
Published in Molecular cell (17.07.2014)
Published in Molecular cell (17.07.2014)
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Increased demand for NAD+ relative to ATP drives aerobic glycolysis
Luengo, Alba, Li, Zhaoqi, Gui, Dan Y., Sullivan, Lucas B., Zagorulya, Maria, Do, Brian T., Ferreira, Raphael, Naamati, Adi, Ali, Ahmed, Lewis, Caroline A., Thomas, Craig J., Spranger, Stefani, Matheson, Nicholas J., Vander Heiden, Matthew G.
Published in Molecular cell (18.02.2021)
Published in Molecular cell (18.02.2021)
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Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin
Gui, Dan Y., Sullivan, Lucas B., Luengo, Alba, Hosios, Aaron M., Bush, Lauren N., Gitego, Nadege, Davidson, Shawn M., Freinkman, Elizaveta, Thomas, Craig J., Vander Heiden, Matthew G.
Published in Cell metabolism (08.11.2016)
Published in Cell metabolism (08.11.2016)
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Altered metabolite levels in cancer: implications for tumour biology and cancer therapy
Sullivan, Lucas B, Gui, Dan Y, Vander Heiden, Matthew G
Published in Nature reviews. Cancer (01.11.2016)
Published in Nature reviews. Cancer (01.11.2016)
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Ferroptosis and Hydrogen Sulfide in Cardiovascular Disease
Wu, Ze-Fan, Yan, Bin-Jie, Luo, Wen, Gui, Dan-Dan, Ren, Zhong, Ma, Yun, Jiang, Zhi-Sheng
Published in Current medicinal chemistry (01.01.2023)
Published in Current medicinal chemistry (01.01.2023)
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Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability
Sullivan, Mark R, Danai, Laura V, Lewis, Caroline A, Chan, Sze Ham, Gui, Dan Y, Kunchok, Tenzin, Dennstedt, Emily A, Vander Heiden, Matthew G, Muir, Alexander
Published in eLife (16.04.2019)
Published in eLife (16.04.2019)
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Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer
Davidson, Shawn M., Papagiannakopoulos, Thales, Olenchock, Benjamin A., Heyman, Julia E., Keibler, Mark A., Luengo, Alba, Bauer, Matthew R., Jha, Abhishek K., O’Brien, James P., Pierce, Kerry A., Gui, Dan Y., Sullivan, Lucas B., Wasylenko, Thomas M., Subbaraj, Lakshmipriya, Chin, Christopher R., Stephanopolous, Gregory, Mott, Bryan T., Jacks, Tyler, Clish, Clary B., Vander Heiden, Matthew G.
Published in Cell metabolism (08.03.2016)
Published in Cell metabolism (08.03.2016)
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Lack of Evidence for PKM2 Protein Kinase Activity
Hosios, Aaron M., Fiske, Brian P., Gui, Dan Y., Vander Heiden, Matthew G.
Published in Molecular cell (03.09.2015)
Published in Molecular cell (03.09.2015)
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Hydrogen sulfide plays a potential alternative for the treatment of metabolic disorders of diabetic cardiomyopathy
Deng, Nian-Hua, Luo, Wen, Gui, Dan-Dan, Yan, Bin-Jie, Zhou, Kun, Tian, Kai-Jiang, Ren, Zhong, Xiong, Wen-Hao, Jiang, Zhi-Sheng
Published in Molecular and cellular biochemistry (2022)
Published in Molecular and cellular biochemistry (2022)
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Pyruvate Kinase Isoform Expression Alters Nucleotide Synthesis to Impact Cell Proliferation
Lunt, Sophia Y., Muralidhar, Vinayak, Hosios, Aaron M., Israelsen, William J., Gui, Dan Y., Newhouse, Lauren, Ogrodzinski, Martin, Hecht, Vivian, Xu, Kali, Acevedo, Paula N. Marín, Hollern, Daniel P., Bellinger, Gary, Dayton, Talya L., Christen, Stefan, Elia, Ilaria, Dinh, Anh T., Stephanopoulos, Gregory, Manalis, Scott R., Yaffe, Michael B., Andrechek, Eran R., Fendt, Sarah-Maria, Vander Heiden, Matthew G.
Published in Molecular cell (08.01.2015)
Published in Molecular cell (08.01.2015)
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SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance
Kim, Dohoon, Fiske, Brian P, Birsoy, Kivanc, Freinkman, Elizaveta, Kami, Kenjiro, Possemato, Richard L, Chudnovsky, Yakov, Pacold, Michael E, Chen, Walter W, Cantor, Jason R, Shelton, Laura M, Gui, Dan Y, Kwon, Manjae, Ramkissoon, Shakti H, Ligon, Keith L, Kang, Seong Woo, Snuderl, Matija, Vander Heiden, Matthew G, Sabatini, David M
Published in Nature (London) (16.04.2015)
Published in Nature (London) (16.04.2015)
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Hydrogen Sulfide Switch Phenomenon Regulating Autophagy in Cardiovascular Diseases
Luo, Wen, Gui, Dan-Dan, Yan, Bin-Jie, Ren, Zhong, Peng, Li-Jun, Wei, Dang-Heng, Liu, Lu-Shan, Zhang, Da-Wei, Jiang, Zhi-Sheng
Published in Cardiovascular drugs and therapy (01.02.2020)
Published in Cardiovascular drugs and therapy (01.02.2020)
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