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Published in Cancer cell (14.11.2016)
Published in Cancer cell (14.11.2016)
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Mechanistic study of dual‐function inhibitors targeting topoisomerase II and Rad51‐mediated DNA repair pathway against castration‐resistant prostate cancer
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Ascleposide, a natural cardenolide, induces anticancer signaling in human castration‐resistant prostatic cancer through Na+/K+‐ATPase internalization and tubulin acetylation
Leu, Wohn‐Jenn, Wang, Ching‐Ting, Hsu, Jui‐Ling, Chen, Ih‐Sheng, Chang, Hsun‐Shuo, Guh, Jih‐Hwa
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A novel HDAC6 inhibitor interferes microtubule dynamics and spindle assembly checkpoint and sensitizes cisplatin‐induced apoptosis in castration‐resistant prostate cancer
Ye, Pei‐Chen, Leu, Wohn‐Jenn, Yeh, Tsung‐Yu, Hsu, Yu‐Tung, Lin, Yi‐Chin, Wei, Zi‐Yuan, Chen, Yi‐Chin, Chiang, Yi‐Chang, Hsu, Jui‐Ling, Chan, She‐Hung, Hsu, Lih‐Ching, Chern, Ji‐Wang, Yu, Chao‐Wu, Guh, Jih‐Hwa
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Dihydroartemisinin–Bile Acid Hybridization as an Effective Approach to Enhance Dihydroartemisinin Anticancer Activity
Marchesi, Elena, Chinaglia, Nicola, Capobianco, Massimo L., Marchetti, Paolo, Huang, Tzu‐En, Weng, Hao‐Cheng, Guh, Jih‐Hwa, Hsu, Lih‐Ching, Perrone, Daniela, Navacchia, Maria Luisa
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Published in ChemMedChem (03.04.2019)
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Anticancer Activity and Molecular Mechanisms of an Ursodeoxycholic Acid Methyl Ester-Dihydroartemisinin Hybrid via a Triazole Linkage in Hepatocellular Carcinoma Cells
Hsu, Ya-Fen, Kung, Fan-Lu, Huang, Tzu-En, Deng, Yi-Ning, Guh, Jih-Hwa, Marchetti, Paolo, Marchesi, Elena, Perrone, Daniela, Navacchia, Maria Luisa, Hsu, Lih-Ching
Published in Molecules (Basel, Switzerland) (01.03.2023)
Published in Molecules (Basel, Switzerland) (01.03.2023)
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Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer
Wang, Yuezhou, Zhang, Lei, Wei, Yanling, Huang, Wei, Li, Li, Wu, An-an, Dastur, Anahita, Greninger, Patricia, Bray, Walter M., Zhang, Chen-Song, Li, Mengqi, Lian, Wenhua, Hu, Zhiyu, Wang, Xiaoyong, Liu, Gang, Yao, Luming, Guh, Jih-Hwa, Chen, Lanfen, Wang, Hong-Rui, Zhou, Dawang, Lin, Sheng-Cai, Xu, Qingyan, Shen, Yuemao, Zhang, Jianming, Jurica, Melissa S., Benes, Cyril H., Deng, Xianming
Published in Cell chemical biology (19.11.2020)
Published in Cell chemical biology (19.11.2020)
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Evaluation of the Anticancer Activity of a Bile Acid-Dihydroartemisinin Hybrid Ursodeoxycholic-Dihydroartemisinin in Hepatocellular Carcinoma Cells
Huang, Tzu-En, Deng, Yi-Ning, Hsu, Jui-Ling, Leu, Wohn-Jenn, Marchesi, Elena, Capobianco, Massimo L, Marchetti, Paolo, Navacchia, Maria Luisa, Guh, Jih-Hwa, Perrone, Daniela, Hsu, Lih-Ching
Published in Frontiers in pharmacology (10.11.2020)
Published in Frontiers in pharmacology (10.11.2020)
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Chalcones Display Anti-NLRP3 Inflammasome Activity in Macrophages through Inhibition of Both Priming and Activation Steps-Structure-Activity-Relationship and Mechanism Studies
Leu, Wohn-Jenn, Chu, Jung-Chun, Hsu, Jui-Ling, Du, Chi-Min, Jiang, Yi-Huei, Hsu, Lih-Ching, Huang, Wei-Jan, Guh, Jih-Hwa
Published in Molecules (Basel, Switzerland) (16.12.2020)
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Phosphodiesterase Type 5 Inhibitors Synergize Vincristine in Killing Castration-Resistant Prostate Cancer Through Amplifying Mitotic Arrest Signaling
Hsu, Jui-Ling, Leu, Wohn-Jenn, Hsu, Lih-Ching, Ho, Chen-Hsun, Liu, Shih-Ping, Guh, Jih-Hwa
Published in Frontiers in oncology (07.08.2020)
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Structure-based design, synthesis and biological evaluation of N-substituted 6H-thiochromeno[2,3–c]quinolin-12(12H)-one as potential breast cancer drugs
Sumitra, Maryam Rachmawati, Chen, Lung-Ching, Tsai, Wei-Chen, Ansar, Muhamad, Lawal, Bashir, Mokgautsi, Ntlotlang, Guh, Jih-Hwa, Wu, Alexander T.H, Huang, Hsu-Shan
Published in Arabian journal of chemistry (01.01.2024)
Published in Arabian journal of chemistry (01.01.2024)
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Antroquinonol displays anticancer potential against human hepatocellular carcinoma cells: A crucial role of AMPK and mTOR pathways
Chiang, Po-Cheng, Lin, Ssu-Chia, Pan, Shiow-Lin, Kuo, Ching-Hua, Tsai, I-Lin, Kuo, Mao-Tien, Wen, Wu-Che, Chen, Peini, Guh, Jih-Hwa
Published in Biochemical pharmacology (15.01.2010)
Published in Biochemical pharmacology (15.01.2010)
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The (+)-Brevipolide H Displays Anticancer Activity against Human Castration-Resistant Prostate Cancer: The Role of Oxidative Stress and Akt/mTOR/p70S6K-Dependent Pathways in G1 Checkpoint Arrest and Apoptosis
Sheng, Yi-Hua, Leu, Wohn-Jenn, Chen, Ching-Nung, Hsu, Jui-Ling, Liu, Ying-Tung, Hsu, Lih-Ching, Hou, Duen-Ren, Guh, Jih-Hwa
Published in Molecules (Basel, Switzerland) (25.06.2020)
Published in Molecules (Basel, Switzerland) (25.06.2020)
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Mechanistic Study of Triazole Based Aminodiol Derivatives in Leukemic Cells-Crosstalk between Mitochondrial Stress-Involved Apoptosis and Autophagy
Chan, She-Hung, Leu, Wohn-Jenn, Swain, Sharada Prasanna, Hsu, Jui-Ling, Hou, Duen-Ren, Guh, Jih-Hwa
Published in International journal of molecular sciences (02.04.2020)
Published in International journal of molecular sciences (02.04.2020)
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Para-Toluenesulfonamide Induces Anti-tumor Activity Through Akt-Dependent and -Independent mTOR/p70S6K Pathway: Roles of Lipid Raft and Cholesterol Contents
Hsu, Jui-Ling, Leu, Wohn-Jenn, Hsu, Lih-Ching, Liu, Shih-Ping, Zhong, Nan-Shan, Guh, Jih-Hwa
Published in Frontiers in pharmacology (13.11.2018)
Published in Frontiers in pharmacology (13.11.2018)
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