From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations
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Published in Molecular biology of the cell (01.02.2016)
Published in Molecular biology of the cell (01.02.2016)
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Woodward, Owen M., Köttgen, Anna, Coresh, Josef, Boerwinkle, Eric, Guggino, William B., Köttgen, Michael, Burg, Maurice B.
Published in Proceedings of the National Academy of Sciences - PNAS (23.06.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (23.06.2009)
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Inhibition of histone deacetylase 6 activity reduces cyst growth in polycystic kidney disease
Cebotaru, Liudmila, Liu, Qiangni, Yanda, Murali K., Boinot, Clement, Outeda, Patricia, Huso, David L., Watnick, Terry, Guggino, William B., Cebotaru, Valeriu
Published in Kidney international (01.07.2016)
Published in Kidney international (01.07.2016)
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Drosophila TRPA1 Channel Is Required to Avoid the Naturally Occurring Insect Repellent Citronellal
Kwon, Young, Kim, Sang Hoon, Ronderos, David S., Lee, Youngseok, Akitake, Bradley, Woodward, Owen M., Guggino, William B., Smith, Dean P., Montell, Craig
Published in Current biology (28.09.2010)
Published in Current biology (28.09.2010)
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Gout-causing Q141K mutation in ABCG2 leads to instability of the nucleotide-binding domain and can be corrected with small molecules
Woodward, Owen M., Tukaye, Deepali N., Cui, Jinming, Greenwell, Patrick, Constantoulakis, Leeza M., Parker, Benjamin S., Rao, Anjana, Köttgen, Michael, Maloney, Peter C., Guggino, William B.
Published in Proceedings of the National Academy of Sciences - PNAS (26.03.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (26.03.2013)
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Syntaxin 8 and the Endoplasmic Reticulum Processing of ΔF508-CFTR
Sabirzhanova, Inna, Boinot, Clément, Guggino, William B., Cebotaru, Liudmila
Published in Cellular physiology and biochemistry (01.01.2018)
Published in Cellular physiology and biochemistry (01.01.2018)
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Correcting the cystic fibrosis disease mutant, A455E CFTR
Cebotaru, Liudmila, Rapino, Daniele, Cebotaru, Valeriu, Guggino, William B
Published in PloS one (08.01.2014)
Published in PloS one (08.01.2014)
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Loss of Chloride Channel ClC-5 Impairs Endocytosis by Defective Trafficking of Megalin and Cubilin in Kidney Proximal Tubules
Christensen, Erik I., Devuyst, Olivier, Dom, Geneviève, Nielsen, Rikke, Van Der Smissen, Patrick, Verroust, Pierre, Leruth, Michèle, Guggino, William B., Courtoy, Pierre J.
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2003)
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Identification of a polycystin-1 cleavage product, P100, that regulates store operated Ca entry through interactions with STIM1
Woodward, Owen M, Li, Yun, Yu, Shengqiang, Greenwell, Patrick, Wodarczyk, Claas, Boletta, Alessandra, Guggino, William B, Qian, Feng
Published in PloS one (23.08.2010)
Published in PloS one (23.08.2010)
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Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents
Guggino, William B, Germino, Gregory G, Hanaoka, Kazushige, Qian, Feng, Boletta, Alessandra, Bhunia, Anil K, Piontek, Klaus, Tsiokas, Leonidas, Sukhatme, Vikas P
Published in Nature (London) (21.12.2000)
Published in Nature (London) (21.12.2000)
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Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway
Karp, Christopher L, Greer, Todd M, Uddin, Jasim, Atabani, Sowsan F, Petasis, Nicos A, Softic, Samir, Xu, Yan, Wills-Karp, Marsha, Guggino, William B, Whitsett, Jeffrey A, Accurso, Frank J, Keledjian, Raquel, Flick, Leah M, Yang, Rong, Belkaid, Yasmine, Park, Kiwon W
Published in Nature immunology (01.04.2004)
Published in Nature immunology (01.04.2004)
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