T Cell Exit from Quiescence and Differentiation into Th2 Cells Depend on Raptor-mTORC1-Mediated Metabolic Reprogramming
Yang, Kai, Shrestha, Sharad, Zeng, Hu, Karmaus, Peer W.F., Neale, Geoffrey, Vogel, Peter, Guertin, David A., Lamb, Richard F., Chi, Hongbo
Published in Immunity (Cambridge, Mass.) (12.12.2013)
Published in Immunity (Cambridge, Mass.) (12.12.2013)
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mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway
Peterson, Timothy R., Sengupta, Shomit S., Harris, Thurl E., Carmack, Anne E., Kang, Seong A., Balderas, Eric, Guertin, David A., Madden, Katherine L., Carpenter, Anne E., Finck, Brian N., Sabatini, David M.
Published in Cell (05.08.2011)
Published in Cell (05.08.2011)
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PTEN Loss in the Myf5 Lineage Redistributes Body Fat and Reveals Subsets of White Adipocytes that Arise from Myf5 Precursors
Sanchez-Gurmaches, Joan, Hung, Chien-Min, Sparks, Cynthia A., Tang, Yuefeng, Li, Huawei, Guertin, David A.
Published in Cell metabolism (05.09.2012)
Published in Cell metabolism (05.09.2012)
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Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity
LAMMING, Dudley W, LAN YE, GUERTIN, David A, SABATINI, David M, BAUR, Joseph A, KATAJISTO, Pekka, GONCALVES, Marcus D, SAITOH, Maki, STEVENS, Deanna M, DAVIS, James G, SALMON, Adam B, RICHARDSON, Arlan, AHIMA, Rexford S
Published in Science (American Association for the Advancement of Science) (30.03.2012)
Published in Science (American Association for the Advancement of Science) (30.03.2012)
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Journal Article
Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism
Tang, Yuefeng, Wallace, Martina, Sanchez-Gurmaches, Joan, Hsiao, Wen-Yu, Li, Huawei, Lee, Peter L, Vernia, Santiago, Metallo, Christian M, Guertin, David A
Published in Nature communications (21.04.2016)
Published in Nature communications (21.04.2016)
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The Complex Roles of Mechanistic Target of Rapamycin in Adipocytes and Beyond
Lee, Peter L, Jung, Su Myung, Guertin, David A
Published in Trends in endocrinology and metabolism (01.05.2017)
Published in Trends in endocrinology and metabolism (01.05.2017)
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Journal Article
Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues
Wallace, Martina, Green, Courtney R, Roberts, Lindsay S, Lee, Yujung Michelle, McCarville, Justin L, Sanchez-Gurmaches, Joan, Meurs, Noah, Gengatharan, Jivani M, Hover, Justin D, Phillips, Susan A, Ciaraldi, Theodore P, Guertin, David A, Cabrales, Pedro, Ayres, Janelle S, Nomura, Daniel K, Loomba, Rohit, Metallo, Christian M
Published in Nature chemical biology (01.11.2018)
Published in Nature chemical biology (01.11.2018)
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Highly selective in vivo labeling of subcutaneous white adipocyte precursors with Prx1-Cre
Sanchez-Gurmaches, Joan, Hsiao, Wen-Yu, Guertin, David A
Published in Stem cell reports (14.04.2015)
Published in Stem cell reports (14.04.2015)
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Journal Article
Raptor /mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease
Lee, Peter L, Tang, Yuefeng, Li, Huawei, Guertin, David A
Published in Molecular metabolism (Germany) (01.06.2016)
Published in Molecular metabolism (Germany) (01.06.2016)
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CellProfiler: image analysis software for identifying and quantifying cell phenotypes
Carpenter, Anne E, Jones, Thouis R, Lamprecht, Michael R, Clarke, Colin, Kang, In Han, Friman, Ola, Guertin, David A, Chang, Joo Han, Lindquist, Robert A, Moffat, Jason, Golland, Polina, Sabatini, David M
Published in Genome biology (01.01.2006)
Published in Genome biology (01.01.2006)
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In vivo isotope tracing reveals the versatility of glucose as a brown adipose tissue substrate
Jung, Su Myung, Doxsey, Will G., Le, Johnny, Haley, John A., Mazuecos, Lorena, Luciano, Amelia K., Li, Huawei, Jang, Cholsoon, Guertin, David A.
Published in Cell reports (Cambridge) (27.07.2021)
Published in Cell reports (Cambridge) (27.07.2021)
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A brown fat-enriched adipokine Adissp controls adipose thermogenesis and glucose homeostasis
Chen, Qingbo, Huang, Lei, Pan, Dongning, Hu, Kai, Li, Rui, Friedline, Randall H, Kim, Jason K, Zhu, Lihua Julie, Guertin, David A, Wang, Yong-Xu
Published in Nature communications (10.12.2022)
Published in Nature communications (10.12.2022)
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Journal Article
Rictor/mTORC2 Loss in the Myf5 Lineage Reprograms Brown Fat Metabolism and Protects Mice against Obesity and Metabolic Disease
Hung, Chien-Min, Calejman, Camila Martinez, Sanchez-Gurmaches, Joan, Li, Huawei, Clish, Clary B., Hettmer, Simone, Wagers, Amy J., Guertin, David A.
Published in Cell reports (Cambridge) (10.07.2014)
Published in Cell reports (Cambridge) (10.07.2014)
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mTOR Complex 1 Plays Critical Roles in Hematopoiesis and Pten-Loss-Evoked Leukemogenesis
Kalaitzidis, Demetrios, Sykes, Stephen M., Wang, Zhu, Punt, Natalie, Tang, Yuefeng, Ragu, Christine, Sinha, Amit U., Lane, Steven W., Souza, Amanda L., Clish, Clary B., Anastasiou, Dimitrios, Gilliland, D. Gary, Scadden, David T., Guertin, David A., Armstrong, Scott A.
Published in Cell stem cell (07.09.2012)
Published in Cell stem cell (07.09.2012)
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mTOR Complex 2 Is Required for the Development of Prostate Cancer Induced by Pten Loss in Mice
Guertin, David A., Stevens, Deanna M., Saitoh, Maki, Kinkel, Stephanie, Crosby, Katherine, Sheen, Joon-Ho, Mullholland, David J., Magnuson, Mark A., Wu, Hong, Sabatini, David M.
Published in Cancer cell (03.02.2009)
Published in Cancer cell (03.02.2009)
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Postprandial Hepatic Lipid Metabolism Requires Signaling through Akt2 Independent of the Transcription Factors FoxA2, FoxO1, and SREBP1c
Wan, Min, Leavens, Karla F., Saleh, Danish, Easton, Rachael M., Guertin, David A., Peterson, Timothy R., Kaestner, Klaus H., Sabatini, David M., Birnbaum, Morris J.
Published in Cell metabolism (05.10.2011)
Published in Cell metabolism (05.10.2011)
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Journal Article
Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females
Fernandez, Sully, Viola, John M., Torres, AnnMarie, Wallace, Martina, Trefely, Sophie, Zhao, Steven, Affronti, Hayley C., Gengatharan, Jivani M., Guertin, David A., Snyder, Nathaniel W., Metallo, Christian M., Wellen, Kathryn E.
Published in Cell reports (Cambridge) (28.05.2019)
Published in Cell reports (Cambridge) (28.05.2019)
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