Tubastatin ameliorates pulmonary fibrosis by targeting the TGFβ-PI3K-Akt pathway
Saito, Shigeki, Zhuang, Yan, Shan, Bin, Danchuk, Svitlana, Luo, Fayong, Korfei, Martina, Guenther, Andreas, Lasky, Joseph A
Published in PloS one (18.10.2017)
Published in PloS one (18.10.2017)
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Targeting Histone Deacetylases in Idiopathic Pulmonary Fibrosis: A Future Therapeutic Option
Korfei, Martina, Mahavadi, Poornima, Guenther, Andreas
Published in Cells (Basel, Switzerland) (12.05.2022)
Published in Cells (Basel, Switzerland) (12.05.2022)
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The European IPF registry (eurIPFreg): baseline characteristics and survival of patients with idiopathic pulmonary fibrosis
Guenther, Andreas, Krauss, Ekaterina, Tello, Silke, Wagner, Jasmin, Paul, Bettina, Kuhn, Stefan, Maurer, Olga, Heinemann, Sabine, Costabel, Ulrich, Barbero, María Asunción Nieto, Müller, Veronika, Bonniaud, Philippe, Vancheri, Carlo, Wells, Athol, Vasakova, Martina, Pesci, Alberto, Sofia, Matteo, Klepetko, Walter, Seeger, Werner, Drakopanagiotakis, Fotios, Crestani, Bruno
Published in Respiratory research (28.07.2018)
Published in Respiratory research (28.07.2018)
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WNT/RYK signaling restricts goblet cell differentiation during lung development and repair
Kim, Hyun-Taek, Yin, Wenguang, Nakamichi, Yuko, Panza, Paolo, Grohmann, Beate, Buettner, Carmen, Guenther, Stefan, Ruppert, Clemens, Kobayashi, Yasuhiro, Guenther, Andreas, Stainier, Didier Y. R.
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2019)
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Aberrant expression and activity of histone deacetylases in sporadic idiopathic pulmonary fibrosis
Korfei, Martina, Skwarna, Sylwia, Henneke, Ingrid, MacKenzie, BreAnne, Klymenko, Oleksiy, Saito, Shigeki, Ruppert, Clemens, von der Beck, Daniel, Mahavadi, Poornima, Klepetko, Walter, Bellusci, Saverio, Crestani, Bruno, Pullamsetti, Soni Savai, Fink, Ludger, Seeger, Werner, Krämer, Oliver Holger, Guenther, Andreas
Published in Thorax (01.11.2015)
Published in Thorax (01.11.2015)
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Epithelial Endoplasmic Reticulum Stress and Apoptosis in Sporadic Idiopathic Pulmonary Fibrosis
Korfei, Martina, Ruppert, Clemens, Mahavadi, Poornima, Henneke, Ingrid, Markart, Philipp, Koch, Miriam, Lang, Gyoergy, Fink, Ludger, Bohle, Rainer-Maria, Seeger, Werner, Weaver, Timothy E, Guenther, Andreas
Published in American journal of respiratory and critical care medicine (15.10.2008)
Published in American journal of respiratory and critical care medicine (15.10.2008)
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FoxO3 an important player in fibrogenesis and therapeutic target for idiopathic pulmonary fibrosis
Al‐Tamari, Hamza M, Dabral, Swati, Schmall, Anja, Sarvari, Pouya, Ruppert, Clemens, Paik, Jihye, DePinho, Ronald A, Grimminger, Friedrich, Eickelberg, Oliver, Guenther, Andreas, Seeger, Werner, Savai, Rajkumar, Pullamsetti, Soni S
Published in EMBO molecular medicine (01.02.2018)
Published in EMBO molecular medicine (01.02.2018)
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Lung CT Densitometry in Idiopathic Pulmonary Fibrosis for the Prediction of Natural Course, Severity, and Mortality
Loeh, Benjamin, Brylski, Lukas T., von der Beck, Daniel, Seeger, Werner, Krauss, Ekaterina, Bonniaud, Philippe, Crestani, Bruno, Vancheri, Carlo, Wells, Athol U., Markart, Philipp, Breithecker, Andreas, Guenther, Andreas
Published in Chest (01.05.2019)
Published in Chest (01.05.2019)
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WNT/RYK signaling functions as an antiinflammatory modulator in the lung mesenchyme
Kim, Hyun-Taek, Panza, Paolo, Kikhi, Khrievono, Nakamichi, Yuko, Atzberger, Ann, Guenther, Stefan, Ruppert, Clemens, Guenther, Andreas, Stainier, Didier Y R
Published in Proceedings of the National Academy of Sciences - PNAS (14.06.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (14.06.2022)
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Regulation and role of the ER stress transcription factor CHOP in alveolar epithelial type-II cells
Klymenko, Oleksiy, Huehn, Martin, Wilhelm, Jochen, Wasnick, Roxana, Shalashova, Irina, Ruppert, Clemens, Henneke, Ingrid, Hezel, Stefanie, Guenther, Katharina, Mahavadi, Poornima, Samakovlis, Christos, Seeger, Werner, Guenther, Andreas, Korfei, Martina
Published in Journal of molecular medicine (Berlin, Germany) (01.07.2019)
Published in Journal of molecular medicine (Berlin, Germany) (01.07.2019)
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Panobinostat plus bortezomib and dexamethasone in previously treated multiple myeloma: outcomes by prior treatment
Richardson, Paul G., Hungria, Vânia T.M., Yoon, Sung-Soo, Beksac, Meral, Dimopoulos, Meletios Athanasios, Elghandour, Ashraf, Jedrzejczak, Wieslaw W., Guenther, Andreas, Nakorn, Thanyaphong Na, Siritanaratkul, Noppadol, Schlossman, Robert L., Hou, Jian, Moreau, Philippe, Lonial, Sagar, Lee, Jae Hoon, Einsele, Hermann, Sopala, Monika, Bengoudifa, Bourras-Rezki, Corrado, Claudia, Binlich, Florence, San-Miguel, Jesús F.
Published in Blood (11.02.2016)
Published in Blood (11.02.2016)
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Adenylate Kinase 4—A Key Regulator of Proliferation and Metabolic Shift in Human Pulmonary Arterial Smooth Muscle Cells via Akt and HIF-1α Signaling Pathways
Wujak, Magdalena, Veith, Christine, Wu, Cheng-Yu, Wilke, Tessa, Kanbagli, Zeki Ilker, Novoyatleva, Tatyana, Guenther, Andreas, Seeger, Werner, Grimminger, Friedrich, Sommer, Natascha, Schermuly, Ralph Theo, Weissmann, Norbert
Published in International journal of molecular sciences (01.10.2021)
Published in International journal of molecular sciences (01.10.2021)
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Noncanonical HIPPO/MST Signaling via BUB3 and FOXO Drives Pulmonary Vascular Cell Growth and Survival
Kudryashova, Tatiana V., Dabral, Swati, Nayakanti, Sreenath, Ray, Arnab, Goncharov, Dmitry A., Avolio, Theodore, Shen, Yuanjun, Rode, Analise, Pena, Andressa, Jiang, Lifeng, Lin, Derek, Baust, Jeffrey, Bachman, Timothy N., Graumann, Johannes, Ruppert, Clemens, Guenther, Andreas, Schmoranzer, Mario, Grobs, Yann, Eve Lemay, Sarah, Tremblay, Eve, Breuils-Bonnet, Sandra, Boucherat, Olivier, Mora, Ana L., DeLisser, Horace, Zhao, Jing, Zhao, Yutong, Bonnet, Sébastien, Seeger, Werner, Pullamsetti, Soni S., Goncharova, Elena A.
Published in Circulation research (04.03.2022)
Published in Circulation research (04.03.2022)
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Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis
Korfei, Martina, Stelmaszek, Daniel, MacKenzie, BreAnne, Skwarna, Sylwia, Chillappagari, Shashipavan, Bach, Anna C, Ruppert, Clemens, Saito, Shigeki, Mahavadi, Poornima, Klepetko, Walter, Fink, Ludger, Seeger, Werner, Lasky, Joseph A, Pullamsetti, Soni S, Krämer, Oliver H, Guenther, Andreas
Published in PloS one (27.11.2018)
Published in PloS one (27.11.2018)
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Dynamic expression of HOPX in alveolar epithelial cells reflects injury and repair during the progression of pulmonary fibrosis
Ota, Chiharu, Ng-Blichfeldt, John-Poul, Korfei, Martina, Alsafadi, Hani N., Lehmann, Mareike, Skronska-Wasek, Wioletta, M. De Santis, Martina, Guenther, Andreas, Wagner, Darcy E., Königshoff, Melanie
Published in Scientific reports (28.08.2018)
Published in Scientific reports (28.08.2018)
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Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease
Kim, Hyun-Taek, Yin, Wenguang, Jin, Young-June, Panza, Paolo, Gunawan, Felix, Grohmann, Beate, Buettner, Carmen, Sokol, Anna M., Preussner, Jens, Guenther, Stefan, Kostin, Sawa, Ruppert, Clemens, Bhagwat, Aditya M., Ma, Xuefei, Graumann, Johannes, Looso, Mario, Guenther, Andreas, Adelstein, Robert S., Offermanns, Stefan, Stainier, Didier Y. R.
Published in Nature communications (02.11.2018)
Published in Nature communications (02.11.2018)
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Enolase-1 promotes plasminogen-mediated recruitment of monocytes to the acutely inflamed lung
Wygrecka, Malgorzata, Marsh, Leigh M., Morty, Rory E., Henneke, Ingrid, Guenther, Andreas, Lohmeyer, Juergen, Markart, Philipp, Preissner, Klaus T.
Published in Blood (28.05.2009)
Published in Blood (28.05.2009)
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Hermansky-Pudlak syndrome type 2 manifests with fibrosing lung disease early in childhood
Hengst, Meike, Naehrlich, Lutz, Mahavadi, Poornima, Grosse-Onnebrink, Joerg, Terheggen-Lagro, Suzanne, Skanke, Lars Høsøien, Schuch, Luise A, Brasch, Frank, Guenther, Andreas, Reu, Simone, Ley-Zaporozhan, Julia, Griese, Matthias
Published in Orphanet journal of rare diseases (27.03.2018)
Published in Orphanet journal of rare diseases (27.03.2018)
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Psychometric properties and minimal important differences of SF-36 in Idiopathic Pulmonary Fibrosis
Witt, Sabine, Krauss, Ekaterina, Barbero, María Asunción Nieto, Müller, Veronika, Bonniaud, Philippe, Vancheri, Carlo, Wells, Athol U, Vasakova, Martina, Pesci, Alberto, Klepetko, Walter, Seeger, Werner, Crestani, Bruno, Leidl, Reiner, Holle, Rolf, Schwarzkopf, Larissa, Guenther, Andreas
Published in Respiratory research (01.03.2019)
Published in Respiratory research (01.03.2019)
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Clinical characteristics of patients with familial idiopathic pulmonary fibrosis (f-IPF)
Krauss, Ekaterina, Gehrken, Godja, Drakopanagiotakis, Fotios, Tello, Silke, Dartsch, Ruth C, Maurer, Olga, Windhorst, Anita, von der Beck, Daniel, Griese, Matthias, Seeger, Werner, Guenther, Andreas
Published in BMC pulmonary medicine (18.07.2019)
Published in BMC pulmonary medicine (18.07.2019)
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