Genetic variability in the regulation of gene expression in ten regions of the human brain
Ramasamy, Adaikalavan, Trabzuni, Daniah, Guelfi, Sebastian, Varghese, Vibin, Smith, Colin, Walker, Robert, De, Tisham, Coin, Lachlan, de Silva, Rohan, Cookson, Mark R, Singleton, Andrew B, Hardy, John, Ryten, Mina, Weale, Michael E
Published in Nature neuroscience (01.10.2014)
Published in Nature neuroscience (01.10.2014)
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Journal Article
A Genome-wide Gene-Expression Analysis and Database in Transgenic Mice during Development of Amyloid or Tau Pathology
Matarin, Mar, Salih, Dervis A., Yasvoina, Marina, Cummings, Damian M., Guelfi, Sebastian, Liu, Wenfei, Nahaboo Solim, Muzammil A., Moens, Thomas G., Paublete, Rocio Moreno, Ali, Shabinah S., Perona, Marina, Desai, Roshni, Smith, Kenneth J., Latcham, Judy, Fulleylove, Michael, Richardson, Jill C., Hardy, John, Edwards, Frances A.
Published in Cell reports (Cambridge) (03.02.2015)
Published in Cell reports (Cambridge) (03.02.2015)
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Journal Article
Imaging genomics discovery of a new risk variant for Alzheimer's disease in the postsynaptic SHARPIN gene
Soheili‐Nezhad, Sourena, Jahanshad, Neda, Guelfi, Sebastian, Khosrowabadi, Reza, Saykin, Andrew J., Thompson, Paul M., Beckmann, Christian F., Sprooten, Emma, Zarei, Mojtaba
Published in Human brain mapping (01.09.2020)
Published in Human brain mapping (01.09.2020)
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Journal Article
eQTL Catalogue 2023: New datasets, X chromosome QTLs, and improved detection and visualisation of transcript-level QTLs
Kerimov, Nurlan, Tambets, Ralf, Hayhurst, James D, Rahu, Ida, Kolberg, Peep, Raudvere, Uku, Kuzmin, Ivan, Chowdhary, Anshika, Vija, Andreas, Teras, Hans J, Kanai, Masahiro, Ulirsch, Jacob, Ryten, Mina, Hardy, John, Guelfi, Sebastian, Trabzuni, Daniah, Kim-Hellmuth, Sarah, Rayner, William, Finucane, Hilary, Peterson, Hedi, Mosaku, Abayomi, Parkinson, Helen, Alasoo, Kaur
Published in PLoS genetics (18.09.2023)
Published in PLoS genetics (18.09.2023)
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Leveraging omic features with F3UTER enables identification of unannotated 3’UTRs for synaptic genes
Sethi, Siddharth, Zhang, David, Guelfi, Sebastian, Chen, Zhongbo, Garcia-Ruiz, Sonia, Olagbaju, Emmanuel O., Ryten, Mina, Saini, Harpreet, Botia, Juan A.
Published in Nature communications (27.04.2022)
Published in Nature communications (27.04.2022)
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Journal Article
Analysis of subcellular RNA fractions demonstrates significant genetic regulation of gene expression in human brain post-transcriptionally
D’Sa, Karishma, Guelfi, Sebastian, Vandrovcova, Jana, Reynolds, Regina H., Zhang, David, Hardy, John, Botía, Juan A., Weale, Michael E., Taliun, Sarah A. Gagliano, Small, Kerrin S., Ryten, Mina
Published in Scientific reports (24.08.2023)
Published in Scientific reports (24.08.2023)
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Journal Article
Unravelling cell type-specific responses to Parkinson's Disease at single cell resolution
Martirosyan, Araks, Ansari, Rizwan, Pestana, Francisco, Hebestreit, Katja, Gasparyan, Hayk, Aleksanyan, Razmik, Hnatova, Silvia, Poovathingal, Suresh, Marneffe, Catherine, Thal, Dietmar R, Kottick, Andrew, Hanson-Smith, Victor J, Guelfi, Sebastian, Plumbly, William, Belgard, T Grant, Metzakopian, Emmanouil, Holt, Matthew G
Published in Molecular neurodegeneration (20.01.2024)
Published in Molecular neurodegeneration (20.01.2024)
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Journal Article
Correction: Unravelling cell type-specific responses to Parkinson's Disease at single cell resolution
Martirosyan, Araks, Ansari, Rizwan, Pestana, Francisco, Hebestreit, Katja, Gasparyan, Hayk, Aleksanyan, Razmik, Hnatova, Silvia, Poovathingal, Suresh, Marneffe, Catherine, Thal, Dietmar R, Kottick, Andrew, Hanson-Smith, Victor J, Guelfi, Sebastian, Plumbly, William, Belgard, T Grant, Metzakopian, Emmanouil, Holt, Matthew G
Published in Molecular neurodegeneration (25.03.2024)
Published in Molecular neurodegeneration (25.03.2024)
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Journal Article
An additional k-means clustering step improves the biological features of WGCNA gene co-expression networks
Botía, Juan A, Vandrovcova, Jana, Forabosco, Paola, Guelfi, Sebastian, D'Sa, Karishma, Hardy, John, Lewis, Cathryn M, Ryten, Mina, Weale, Michael E
Published in BMC systems biology (12.04.2017)
Published in BMC systems biology (12.04.2017)
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Journal Article
Transcriptomic and genetic analyses reveal potential causal drivers for intractable partial epilepsy
Guelfi, Sebastian, Botia, Juan A, Thom, Maria, Ramasamy, Adaikalavan, Perona, Marina, Stanyer, Lee, Martinian, Lillian, Trabzuni, Daniah, Smith, Colin, Walker, Robert, Ryten, Mina, Reimers, Mark, Weale, Michael E, Hardy, John, Matarin, Mar
Published in Brain (London, England : 1878) (01.06.2019)
Published in Brain (London, England : 1878) (01.06.2019)
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Journal Article
Increased brain expression of GPNMB is associated with genome wide significant risk for Parkinson’s disease on chromosome 7p15.3
Murthy, Megha N., Blauwendraat, Cornelis, Guelfi, Sebastian, Hardy, John, Lewis, Patrick A., Trabzuni, Daniah
Published in Neurogenetics (01.07.2017)
Published in Neurogenetics (01.07.2017)
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Journal Article
Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at 16q11.2 and MAPT H1 loci
Soutar, Marc P M, Melandri, Daniela, O'Callaghan, Benjamin, Annuario, Emily, Monaghan, Amy E, Welsh, Natalie J, D'Sa, Karishma, Guelfi, Sebastian, Zhang, David, Pittman, Alan, Trabzuni, Daniah, Verboven, Anouk H A, Pan, Kylie S, Kia, Demis A, Bictash, Magda, Gandhi, Sonia, Houlden, Henry, Cookson, Mark R, Kasri, Nael Nadif, Wood, Nicholas W, Singleton, Andrew B, Hardy, John, Whiting, Paul J, Blauwendraat, Cornelis, Whitworth, Alexander J, Manzoni, Claudia, Ryten, Mina, Lewis, Patrick A, Plun-Favreau, Hélène
Published in Brain (London, England : 1878) (19.12.2022)
Published in Brain (London, England : 1878) (19.12.2022)
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Journal Article
Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases
Ferrari, Raffaele, Wang, Yunpeng, Vandrovcova, Jana, Guelfi, Sebastian, Witeolar, Aree, Karch, Celeste M, Schork, Andrew J, Fan, Chun C, Brewer, James B, Momeni, Parastoo, Schellenberg, Gerard D, Dillon, William P, Sugrue, Leo P, Hess, Christopher P, Yokoyama, Jennifer S, Bonham, Luke W, Rabinovici, Gil D, Miller, Bruce L, Andreassen, Ole A, Dale, Anders M, Hardy, John, Desikan, Rahul S
Published in Journal of neurology, neurosurgery and psychiatry (01.02.2017)
Published in Journal of neurology, neurosurgery and psychiatry (01.02.2017)
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Journal Article
Genetic variability in response to amyloid beta deposition influences Alzheimer's disease risk
Salih, Dervis A, Bayram, Sevinc, Guelfi, Sebastian, Reynolds, Regina H, Shoai, Maryam, Ryten, Mina, Brenton, Jonathan W, Zhang, David, Matarin, Mar, Botia, Juan A, Shah, Runil, Brookes, Keeley J, Guetta-Baranes, Tamar, Morgan, Kevin, Bellou, Eftychia, Cummings, Damian M, Escott-Price, Valentina, Hardy, John
Published in Brain communications (01.01.2019)
Published in Brain communications (01.01.2019)
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Journal Article
Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis
Ferrari, Raffaele, Forabosco, Paola, Vandrovcova, Jana, Botía, Juan A, Guelfi, Sebastian, Warren, Jason D, Momeni, Parastoo, Weale, Michael E, Ryten, Mina, Hardy, John
Published in Molecular neurodegeneration (24.02.2016)
Published in Molecular neurodegeneration (24.02.2016)
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Journal Article
693. Identification, Regulation and Characterisation of Transcribed Intergenic Regions in Human Substantia Nigra and Putamen
Ryten, Mina, Guelfi, Sebastian, D׳Sa, Karishma, Botia, Juan, Vandrocova, Jana, Trabzuni, Daniah, Ramasamy, Adaikalavan, Smith, Colin, Hardy, John, Weale, Michael
Published in Biological psychiatry (1969) (15.05.2017)
Published in Biological psychiatry (1969) (15.05.2017)
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Journal Article
Identification, Regulation and Characterisation of Transcribed Intergenic Regions in Human Substantia Nigra and Putamen
Ryten, Mina, Guelfi, Sebastian, D׳Sa, Karishma, Botia, Juan, Vandrocova, Jana, Trabzuni, Daniah, Ramasamy, Adaikalavan, Smith, Colin, Hardy, John, Weale, Michael
Published in Biological psychiatry (1969) (2017)
Published in Biological psychiatry (1969) (2017)
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Journal Article
Incomplete annotation has a disproportionate impact on our understanding of Mendelian and complex neurogenetic disorders
Zhang, David, Guelfi, Sebastian, Garcia-Ruiz, Sonia, Costa, Beatrice, Reynolds, Regina H., D’Sa, Karishma, Liu, Wenfei, Courtin, Thomas, Peterson, Amy, Jaffe, Andrew E., Hardy, John, Botía, Juan A., Collado-Torres, Leonardo, Ryten, Mina
Published in Science advances (01.06.2020)
Published in Science advances (01.06.2020)
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Journal Article
Incomplete annotation has a disproportionate impact on our understanding of Mendelian and complex neurogenetic disorders
Zhang, David, Guelfi, Sebastian, Garcia-Ruiz, Sonia, Costa, Beatrice, Reynolds, Regina H, D'Sa, Karishma, Liu, Wenfei, Courtin, Thomas, Peterson, Amy, Jaffe, Andrew E, Hardy, John, Botía, Juan A, Collado-Torres, Leonardo, Ryten, Mina
Published in Science advances (10.06.2020)
Published in Science advances (10.06.2020)
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